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| 1 | Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis显示文摘AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial peritonitis.METHODS:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid polymorphonuclear cell count(PMNLs) ≥ 250 cells/mm 3 at admission] were empirically treated with cefotaxime sodium 2 g/12 h and volume expansion by intravenous human albumin.All patients were subjected to history taking,complete examination,laboratory tests(including a complete blood cell count,prothrombin time,biochemical tests of liver and kidney function,and fresh urine sediment),chest X-ray,a diagnostic abdominal paracentesis,and the sample subjected to total and differential cell count,chemical examination,aerobic and anaerobic cultures.Patients were divided after 2 d by a second ascitic PMNL count into group Ⅰ;patients sensitive to cefotaxime(n = 81),group Ⅱ(n = 19);cases resistant to cefotaxime(less than 25% decrease in ascitic PMNL count).Patients of group Ⅱ were randomly assigned into meropenem(n = 11) or levofloxacin(n = 8) subgroups.All patients performed an end of treatment ascitic PMNL count.Patients were considered improved when:PMNLs decreased to < 250 cells/mm 3,no growth in previously positive culture cases,and improved clinical manifestations with at least 5 d of antibiotic therapy.RESULTS:Age,sex,and Child classes showed no significant difference between group Ⅰ and group Ⅱ.Fever and abdominal pain were the most frequent manifestations and were reported in 82.7% and 80.2% of patients in group Ⅰ and in 94.7% and 84.2% of patients in group Ⅱ,respectively.Patients in group Ⅱ had a more severe ascitic inflammatory response than group Ⅰ and this was demonstrated by more ascitic lactate dehydrogenase(LDH) [median:540 IU/L(range:150-1200 IU/L) vs median:240 IU/L(range:180-500 IU/L),P = 0.000] and PMNL [median:15 000 cell/mm 3(range:957-23 822 cell/mm 3) vs 3400 cell/mm 3(range:695-26 400 cell/mm 3),P = 0.000] counts.Ascitic fluid culture was positive in 32% of cases.Cefotaxime failed in 19% of patients;of these patients,11(100%) responded to meropenem and 6(75%) responded to levofloxacin.Two patients with failed levofloxacin therapy were treated according to the in vitro culture and sensitivity(one case was treated with vancomycin and one case was treated with ampicillin/sulbactam).In group Ⅱ the meropenem subgroup had higher LDH(range:108-860 IU/L vs 120-491 IU/L,P = 0.042) and PMNL counts(range:957-23 822 cell/mm 3 vs 957-15 222 cell/mm 3,P = 0.000) at initiation of the alternative antibiotic therapy;there was no significant difference in the studied parameters between patients responsive to meropenem and patients responsive to levofloxacin at the end of therapy(mean ± SD:316.01 ± 104.03PMNLs/mm 3 vs 265.63 ± 69.61 PMNLs/mm 3,P = 0.307).The isolated organisms found in group Ⅱ were;enterococci,acinetobacter,expanded-spectrum β-lactamase producing Escherichia coli,β-lactamase producing Enterobacter and Staphylococcus aureus.CONCLUSION:Empirical treatment with cefotaxime is effective in 81% of cases;meropenem is effective in cefotaxime-resistant cases. | Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf Mohamed Hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly | 2013 | World Journal of Gastroenterology2013，19，8： | 13 |
| 2 | 外植体的种类及消毒方式对椰枣胚性愈伤组织诱导的影响显示文摘为了研究不同外植体及消毒方式对椰枣胚性愈伤组织诱导的影响,在MS培养基的基础上,以椰枣幼苗茎尖生长组织、幼嫩叶片、5年生大树的茎尖生长组织和种胚为外植体,对这4种材料分别用75%乙醇、2%次氯酸钠、2%山农一号(Ⅰ)型组合进行消毒。研究不同消毒方式对这4种典型取材部位的消毒效果及外植体后期的胚性愈伤诱导情况。结果表明:胚性愈伤组织诱导率,种胚>大树茎尖生长点>幼苗茎尖生长点>幼嫩叶片,其中种胚的诱导率最高,达到66.67%,幼嫩叶片的诱导率最低,为26.67%;最佳消毒方案是:75%乙醇+2%次氯酸钠+2%山农一号(Ⅰ)型,种胚、幼苗茎尖生长点、大树茎尖生长点、幼嫩叶片的成活率分别为86.67%、93.33%、83.33%、70.00%。愈伤组织最佳诱导培养基:MS+3.5 g/L植物凝胶+30 g/L蔗糖+1 g/L活性炭+150 mg/L谷氨酰胺+0.3 mg/L烟酸+0.5 mg/L盐酸吡哆醇+100 mg/L肌醇+0.7 g/L磷酸二氢钾+2 mg/L6-BA+3 mg/L NAA+5 mg/L 2,4-D+1 mg/L 2-ip。综上结果,种胚、茎尖生长点部位更适合作为胚性愈伤组织诱导的外植体。 | 张宁 王义 刘心语 符海泉 李东霞 Walid Badawy Abdelaala 王富有 徐中亮 | 2022 | 分子植物育种2022，20，10： | 3 |
| 3 | Gossypol inhibits proliferation of endometrioma cells in culture显示文摘瞄准:为了在子宫内膜瘤评估 anti-proliferative 活动和棉子酚的 mitochondrial 毒性,房间在短期的文化维持了。方法:三 endometriomacell 从病人衬里的(A) 与 25 或 50 nmol/L 棉子酚被对待多达 12 天。细胞生长上的棉子酚的效果被记录。(B) A 磷光氧分析器被用来从病人在六根子宫内膜瘤房间线的 mitochondrial 耗氧量上决定棉子酚的效果。(C) 在从病人的三根子宫内膜瘤房间线的细胞的棉子酚累积被高压的液相色谱法测量。结果:endometriomacells 的增长被 25 和 50 nmol/L 棉子酚禁止。子宫内膜瘤房间的呼吸被 10 μ m ol/L 棉子酚禁止。细胞的棉子酚在与 10 和 0.3 μ m ol/L 棉子酚为 24 h 被对待的子宫内膜瘤房间线被检测。结论:棉子酚在有教养的子宫内膜瘤房间上调用有势力毒性。 | Shawky Z. A. Badawy Abdul-Kader Souid Violeta Cuenca Nicholas Montalto Frances Shue | 2007 | Asian Journal of Andrology2007，9，3： | 3 |
| 4 | Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16[alpha ]-hydroxylation of 17[beta ]-estradiol显示文摘 | Alaa F. Badawi Ercole L. Cavalieri Eleanor G. Rogan | 2001 | Metabolism2001，，9： | 3 |
| 5 | Epidemiological,clinical and laboratory findings of infectious keratitis at Mansoura Ophthalmic Center,Egypt显示文摘● AIM: To analyze the epidemiological, clinical and laboratory findings of infectious keratitis. ● METHODS: A retrospective study on cases of infective keratitis, attended our institution from Mar. 2013 to Feb. 2015, was done at Mansoura Ophthalmic Center, Egypt. Corneal scrapings were performed and processed for direct microscopy and culture in appropriate media using standard laboratory protocols. ● RESULTS: Out of 245 patients enrolled for study, 247 corneal scrapings were obtained. Ocular trauma was the most common predisposing factor(51.4%), followed by diabetes mellitus(15.1%). Cultures were positive in 110 scraping samples(44.5%): 45.5% samples had pure fungal infection, 40% had pure bacterial infections and 10% had mixed fungal and bacterial growths. Acanthamoeba was detected in 5(4.5%) samples. The most common fungal pathogen was Aspergillus spp.(41%). The most common bacterial isolates were Staphylococcus aureus(38.2%) and Pseudomonas aeruginosa(21.8%).● CONCLUSION: Incidence of fungal keratitis is high in our region. Therapeutic approach can initially be based on clinical features and sensitivity/resistance patterns. Microbiological research should direct the antimicrobial treatment. Antibiotic resistance to fluoroquinolones and aminoglycosides is an important consideration. | Amani E Badawi Dalia Moemen Nora L El-Tantaw | 2017 | International Journal of Ophthalmology(English edition)2017，10，1： | 2 |
| 6 | Electrochemical and XPS investigations of cobalt in KOH solutions 显示文摘 | Ismail K M Badawy W A | 2000 | J Appl Electrochem2000，30，11： | 2 |
| 7 | Serum autoantibodies positivity prevalence in patients with chronic HCV and impact on pegylated interferon and ribavirin treatment response显示文摘 | Marwa Khairy Maissa El‐Raziky Wafaa El‐Akel Mohamed S. Abdelbary Hany Khatab Badawy El‐Kholy Gamal Esmat Mahassen Mabrouk | 2013 | Liver Int2013，，10： | 2 |
| 8 | A(t, m, n)-Group Oriented Secret Sharing Scheme显示文摘Basic(t, n)-Secret sharing(SS) schemes share a secret among n shareholders by allocating each a share. The secret can be reconstructed only if at least t shares are available. An adversary without a valid share may obtain the secret when more than t shareholders participate in the secret reconstruction. To address this problem, the paper introduces the notion and gives the formal definition of(t, m, n)-Group oriented secret sharing(GOSS); and proposes a(t, m, n)-GOSS scheme based on Chinese remainder theorem. Without any share verification or user authentication, the scheme uses Randomized components(RC) to bind all participants into a tightly coupled group, and ensures that the secret can be recovered only if all m(m ≥ t) participants in the group have valid shares and release valid RCs honestly. Analysis shows that the proposed scheme can guarantee the security of the secret even though up to m-1 RCs or t-1 shares are available for adversaries. Our scheme does not depend on any assumption of hard problems or one way functions. | MIAO Fuyou FAN Yuanyuan WANG Xingfu XIONG Yan Moaman Badawy | 2016 | Chinese Journal of Electronics2016，25，1： | 2 |
| 9 | Electrochemical behaviour of vanadium in aqueous solutions of different pH 显示文摘 | Al-Kharafi F M Badawy W A | 1997 | Electrochimica Acta1997，42，4： | 1 |
| 10 | Enhanced tolerance to salt stress and water deficit by over-expressing superoxide dismutase in tobacco(Nicotiana tabacum) chloroplasts 显示文摘 | Badawi G H Yamauchi Y Shimada E | 2004 | Plant Sci2004，166，： | 1 |
| 11 | Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16 α-hydroxylation of 17 β-estradiol 显示文摘 | Badawi AF Cavalieri EL Rogan EG | 2001 | Metabolism2001，50，9： | 1 |
| 12 | Geometrical and light-induced effects on back-gating in ion-implanted GaAs MESFET's显示文摘 | SUBRAMANIUM S BHATTACHARYA P K STAKER K J GHOSH G L BADAWI M H | 1985 | IEEE Trans Electron Devices1985，32，1： | 1 |
| 13 | Laparoscopic cystogastrotomy for pancreatic pseudocyst is safe and effective显示文摘 | Smadja C Badawy A Vons C | | 0，，： | 1 |
| 14 | A mechanistic appraisal of cognitive dysfunction in epilepsy显示文摘 | Badawy RA Johnson KA Cook MJ | | 0，，8： | 1 |
| 15 | Clomiphene citrate or letrozole for ovulation inductionin women with polycystic ovarian syndrome:a prospective randomized trial显示文摘 | Badawy A Abdel AM I Abulatta M | 2009 | Fertil Steril2009，92，3： | 1 |
| 16 | The use of single versus double dose of intra- vaginal prostaglandin E2' misoprostol' prior to abdominal myomectomy: a randomized controlled clinical trial显示文摘 | Ragab A Khaiary M Badawy A | 2014 | J Reprod Infer- til2014，15，3： | 1 |
| 17 | Randomized controlled trial of three doses of letrozole for ovulation induction in patients with unexplained infertility 显示文摘 | Badawy A Metwally M Fawzy M | 2007 | Reprod Biomed Online2007，14，5： | 1 |
| 18 | Modulation of the expression of the cyclooxygenase 1 and 2 genes in rat mammary glands: role of hormonal status and dietary fat显示文摘 | el-Sohemy A Stephen LL | 1999 | Adv Exp Med Biol1999，469，： | 1 |
| 19 | The points of nerve entry and intramuscular nerve branchings in the human muscles of mastication显示文摘 | Rakhawy MT Shehata SH Badawy ZH | 1976 | Acta anat1976，94，： | 1 |
| 20 | Alcohol,aggression and serotonin:metabolic aspects显示文摘 | Badawy A | 1998 | Alcohol1998，33，： | 1 |
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