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| 1 | Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis显示文摘AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of ceruleaninduced acute pancreatitis (AP).METHODS: Seventy male Wistar albino rats were divided into seven groups. Acute edematous pancreatitis was induced by subcutaneous cerulein injection (20 μg/kg) four times at 1-h intervals. CAPE (30 mg/kg) was given by subcutaneous injection at the beginning (CAPE 1 group) and 12 h after the last cerulein injection (CAPE 2 group). Serum amylase, lipase, white blood cell count, and tumor necrosis factor (TNF)-α levels were measured, and pancreatic histopathology was assessed. RESULTS: In the AP group, amylase and lipase levels were found to be elevated and the histopathological evaluation showed massive edema and inflammation of the pancreas, with less fatty necrosis when compared with sham and control groups. Amylase and lipase levels and edema formation decreased signif icantly in the CAPE therapy groups (P < 0001); especially in the CAPE 2 group, edema was improved nearly completely (P = 0001). Inflammation and fatty necrosis were partially recovered by CAPE treatment. The pathologicalresults and amylase level in the placebo groups were similar to those in the AP group. White blood cell count and TNF-α concentration was nearly the same in the CAPE and placebo groups.CONCLUSION: CAPE may be useful agent in treatment of AP but more experimental and clinical studies are needed to support our observation of benef icial effects of CAPE before clinical usage of this agent. | Mehmet Buyukberber M Cemil Savas Cahit Bagci Mehmet Koruk Murat T Gulsen Ediz Tutar Tugba Bilgic Nurdan Ceylan | 2009 | World Journal of Gastroenterology2009，15，41： | 4 |
| 2 | In-situ combustion laboratory studies of Turkish heavy oil reservoirs显示文摘 | Bagci S Kok M V | 2001 | Fuel Processing Technology2001，74，2： | 2 |
| 3 | Effect of different adsorbents on purification of used sunflower seed oil utilized for frying 显示文摘 | MASKAN M BAGCI H | 2003 | Eur Food Res Technol2003，217，： | 1 |
| 4 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 5 | Moving object detection using adaptive subband decomposition and fractional lower order statistics in video sequences显示文摘 | BAGCI M YARDIMCI Y CETIN A E | 2002 | Signal Process2002，82，12： | 1 |
| 6 | Fast and rigorous analysis of EMC/EMI phenomena on electrically large and complex cable-loaded structures显示文摘 | Bagci H Yilmaz A E Jin J M | 2007 | IEEE Transactions on Electromagnetic Compatibility2007，49，2： | 1 |
| 7 | Elevated plasma homocysteine concentrations as a predictor of steatohepatitis in patients with non-alcoholic fatty liver disease显示文摘 | M Gulsen Z Yesilova S Bagci | 2005 | J Gastroenterol Hepatol2005，20，9： | 1 |
| 8 | Moving object detection using adaptive subband decomposition and fractional lower order statistics in video sequences显示文摘 | BAGCI M YARDIMCI Y CETIN A E | 2002 | Signal Process2002，82，12： | 1 |
| 9 | Elevated plasma homocysteine concentrations as a predictor of steatohepatitis in patients with NAFLD显示文摘 | Gulsen M Yesilova Z Bagci S | 2005 | Hepatology2005，20，5： | 1 |
| 10 | In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats显示文摘 | Cagli K Bagci C Gulec M | 2005 | Ann Clin Lab Sci2005，35，4： | 1 |
| 11 | Structural and dynamical properties of zinc-blende GaN, AIN, BN, and their (110) surfaces 显示文摘 | Tutiincu H M Bagci S Srivastava G P | 2005 | Physical Review B2005，71，19： | 1 |
| 12 | Current-voltage (l-V) characteristics of armchair graphene nanoribbons under uniaxial strain显示文摘 | TOPSAKAL M BAGCI V M CIRACI S | 2010 | Phys Rev B2010，81，20： | 1 |
| 13 | Clinical characteristics of viral intestinal infection in preterm and term neonates显示文摘 | Bagci S Eis-Hubinger A M Yassin A F | 2010 | Eur J Clin Microbiol Infect Dis2010，29，10： | 1 |
| 14 | Thickness profiles of retinal layers by optical coherence tomography image segmentation 显示文摘 | Bagci AM Shahidi M Ansari R | 2008 | Am J Ophthalmol2008，146，： | 1 |
| 15 | In-situ combustion laboratory studies of Turkish heavy oil reservoirs显示文摘 | Bagci S Kok M V | 2001 | Fuel Processing Technology2001，74，2： | 1 |
| 16 | Effect of different adsorbents onpurification of used sunflower seed oil utilized for frying 显示文摘 | MASKAN M BAGCI H | 2003 | European Food Research and Technology2003，217，： | 1 |
| 17 | In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats 显示文摘 | Cagli K Bagci C Gulec M | 2005 | Ann Clin Lab Sci2005，35，4： | 1 |
| 18 | Determination of formatlon damage in limestone reservoirs and its effect on production显示文摘 | Kok M V Turksoy U | 2000 | Journal of Petroleum Science and Engineering2000，28，12： | 1 |
| 19 | Systematic study of adsorption of single atoms on a carbon nano- tube显示文摘 | Durgun E Dag S Bagci V M K | 2003 | Phys Rev B2003，67，20： | 1 |
| 20 | In Vivo Effects of Caffeic Acid Phenethyl Ester on Myocardial Ischemia-Reperfusion Injury and Apoptotic Changes in Rats显示文摘 | Cagli K Bagci C Gulec M | 2005 | Ann Clin Lab Sci2005，35，4： | 1 |
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