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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | The folkestone bed sands:microfabric and strength显示文摘 | Richards N P Barton M E | 1999 | Study Journal of Engineering Geology1999，32，： | 2 |
| 3 | 与久坐者相比,职业运动员的肠道菌群在代谢组分,尤其是功能代谢水平上有所不同显示文摘目的有证据表明肠道菌群以及影响其结构和活性的因素在人类代谢、免疫和发育过程中发挥作用。我们曾报道,与久坐者相比,诸如职业运动员,配有相应饮食的极度体育活动者肠道菌群种属和代谢组分发生了改变。这次我们重点研究这些因素对菌群功能/代谢活动的影响,以进一步揭示运动者和久坐者间的差别。方法对专业国际橄榄球联盟球员(样本数为40例)和对照(样本数为46例)的肠道菌群进行代谢表型和功能宏基因组分析,并将结果与生活方式指标(比如饮食习惯)和临床评估指标(比如血清肌酸激酶)进行关联。结果与对照相比,运动员组中与肌肉更新和整体健康相关的信号通路(比如:氨基酸、抗生素生物合成和碳水化合物代谢)和肠道菌群代谢产物(比如:短链脂肪酸乙酸酯、丙酸酯和丁酸酯)有所增加。结论运动和久坐相比,其肠道菌群在宏基因组和代谢组学上比组织水平显示出更大差异,拓展了饮食.运动.肠道微生态模式新视野。 | Barton W Penney NC Cronin O Garcia-Perez I Molloy MG Holmes E Shanahan F Cotter PD O'Sullivan O 毛玲娜 宋震亚 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 4 | Recognition and reaction of metallointercalators with DNA显示文摘 | ERKKILA K E ODOM D T BARTON J K | 1999 | Chem Rev1999，99，： | 1 |
| 5 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorohic DNA assay显示文摘 | Duncan S Barton J E O'brien P A | 1993 | Mycol Res1993，15，： | 1 |
| 6 | Azithromycin as the first-line treatment of non-gonococcal urethritis (NGU): a study of follow-up rates, contact attendance and patients' treatment preference显示文摘 | Carlin E M Barton S E | 1996 | Int J STD AIDS1996，7，3： | 1 |
| 7 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorphic DNA assay显示文摘 | Duncan S Barton J E O′Brien P A | 1993 | Mycol Res1993，97，9： | 1 |
| 8 | Suggested methods for the quantitative descrip- tion of discontinuities in rock masses 显示文摘 | Barton W E | 1978 | Int J Rock Mech Min Sci & Geomech Abstr1978，15，6： | 1 |
| 9 | Pattern and consequences of interspecific competition in natural communities:a review of field experiments with plants显示文摘 | Goldberg D E Barton A M | 1992 | American Naturalist1992，139，： | 1 |
| 10 | Crural repair permits morbidly obese patients with not large hiatal hernia to choose laparoscopic adjustable banding as a bariatric surgical treatment显示文摘 | Frezza E E Barton A Wachtel M S | 2008 | Obes Surg2008，18，5： | 1 |
| 11 | The voices of breastfeeding resource nurses显示文摘 | Froh E B Flynn-Roth R Barton S | 2015 | Journal of Obstetric Gynecologic & Neonatal Nursing2015，44，3： | 1 |
| 12 | Expectant management of severe preeclampsia at 27 (0/7) to 33 ( 6/7 ) weeks gestation : maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management 显示文摘 | BOMBRYS A E BARTON J R HABLI M | 2009 | American Journal of Perinatology2009，26，6： | 1 |
| 13 | Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic,an angiotensin-converting enzyme inhibitor,or an angioteasin receptor blocker显示文摘 | O'Brien E Barton J Nussberger J | 2007 | Hypertension2007，49，： | 1 |
| 14 | Characterizing perflu- orooctanoate in ambient air near the fence line of a manufacturing facility : Comparing modeled and monitored values 显示文摘 | Barton C Butler L E Zarzecki C J | 2006 | Journal of Air Waste Managenvent Association2006，56，1： | 1 |
| 15 | The manahement of placenta percreta: con-servative and operative stragtegies 显示文摘 | O'Brien JM Barton J R Donaldson E S | 1996 | Am J Obstet Gynecol1996，175，6： | 1 |
| 16 | Expectant management of severe preeclampsia at 27(0/7) to 33(6/7) weeks' gestation:maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management显示文摘 | Bombrys A E Barton J R Habli M | 2009 | Am J Perinatol2009，26，6： | 1 |
| 17 | On demonstrating DNA intercalation显示文摘 | Long E C Barton J K | 1990 | Accounts of Chemical Research1990，23，9： | 1 |
| 18 | Science显示文摘 | Dandliker P J Holmlin R E Barton J K | 1997 | 275:14651997，275，： | 1 |
| 19 | On demonstration DNA intercalation显示文摘 | Long E C Barton J K | 1990 | Accounts Chem Res1990，23，9： | 1 |
| 20 | Analysis of variation in isolates of Rhizoctonia solani by random amplifyied polymorphic DNA assay显示文摘 | Duncan S Barton J E O'-Brien P A | 1993 | Mycological Research1993，97，9： | 1 |
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