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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997,,2: | 6 |
| 2 | 青少年甘油磷酸胆碱代谢和心血管病的危险因素:一项队列研究显示文摘甘油磷酸胆碱(glycerophosphocholine,GPC)代谢物可调节动脉粥样硬化,从而导致心血管病风险。临床前期心血管病可能从青春期就开始。研究人员应用靶向血清脂质组学鉴定一组新的GPC,并测试在青春期时这些GPC中的任何一种是否与心血管病传统危险因子,如过量内脏脂肪、升高的血压、胰岛素抵抗和致动脉粥样硬化血脂异常相关。 | Syme C Czajkowski S Shin J Abrahamowicz M Leonard G Perron M Richer L Veillette S Gaudet D Strug L Wang Y Xu H Taylor G Paus T Bennett S Pausova Z 刘莉 叶鹏 | 2016 | 中华高血压杂志2016,24,10: | 3 |
| 3 | Serelaxin increases the antifibrotic action of rosiglitazone in a model of hepatic fibrosis显示文摘AIM To determine the effect of combined serelaxin and rosiglitazone treatment on established hepatic fibrosis.METHODS Hepatic fibrosis was induced in mice by carbon tetrachloride administration for 6 wk, or vehicle alone(nonfibrotic mice). For the final 2 wk, mice were treated with rosiglitazone, serelaxin, or both rosiglitazone and serelaxin. Serum liver enzymes and relaxin levels were determined by standard methods. The degree of liver collagen content was determined by histology and immunohistochemistry. Expression of type?Ⅰ?collagen was determined by quantitative PCR. Activation of hepatic stellate cells was assessed by alpha-smoothmuscle actin(SMA) levels. Liver peroxisome proliferator activated receptor-gamma coactivator 1 alpha(PGC1α) was determined by Western blotting.RESULTS Treatment of mice with CCl4 resulted in hepatic fibrosis as evidenced by increased liver enzyme levels(ALT and AST), and increased liver collagen and SMA. Monotherapy with either serelaxin or rosiglitazone for 2 wk was generally without effect. In contrast, the combination of serelaxin and rosiglitazone resulted in significantly improved ALT levels(P < 0.05). Total liver collagen content as determined by Sirius red staining revealed that only combination treatment was effective in reducing total liver collagen(P < 0.05). These results were supported by immunohistochemistry for type?Ⅰ?collagen, in which only combination treatment reduced fibrillar collagen levels(P < 0.05). The level of hepatic stellate cell activation was modestly, but significantly, reduced by serelaxin treatment alone, but combination treatment resulted in significantly lower SMA levels. Finally, while hepatic fibrosis reduced liver PGC1α levels, the combination of serelaxin and rosiglitazone resulted in restoration of PGC1α protein levels.CONCLUSION The combination of serelaxin and rosiglitazone treatment for 2 wk was effective in significantly reducing established hepatic fibrosis, providing a potential new treatment strategy. | Robert G Bennett Ronda L Simpson Frederick G Hamel | 2017 | World Journal of Gastroenterology2017,23,22: | 2 |
| 4 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013,,2: | 2 |
| 5 | Circumventricular organs:a Novel site of neural stem cells in the adult brain显示文摘 | Bennett L Yang M Enikolopov G | | 0,,03: | 2 |
| 6 | Understanding relationships among multiple ecosystem services显示文摘 | Bennett E M Peterson G D Gordon L J | 2009 | Ecol Let2009,,12: | 1 |
| 7 | Circumventricular or- gans: a novel site of neural stem cells in the adult brain 显示文摘 | Bennett L Yang M Enikolopov G | 2009 | Mol Cell Neurosci2009,41,3: | 1 |
| 8 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008,,6: | 1 |
| 9 | Influence of processiing on fllsarium mycotoxins in contaminated grains 显示文摘 | BENNETT G A RICHARD J L | 1996 | Food Technol1996,50,5: | 1 |
| 10 | Comparativemapping of BTA15 and HSAll including a region containing a QTL for meat tenderness显示文摘 | Rexroad C E Bennett G L Stone R T | 2001 | Mamm Genome2001,12,: | 1 |
| 11 | Gynecologic causes of acute pelvic pain: spectrum of CT findings显示文摘 | Bennett G L Slywotzky C M Giovanniello G | 2002 | Radiographics2002,22,4: | 1 |
| 12 | CT findings in acute gangrenous cholecystitis显示文摘 | Bennett G L Rusinek H Lisi V | 2002 | AJR Am J Roentgenol2002,178,2: | 1 |
| 13 | First year Wilkinson Microwave Anisotropy Probe (WMAP)observations:preliminary maps and basic results显示文摘 | BENNETT C L HALPERN M HINSHAW G | 2003 | Astrophys J2003,,: | 1 |
| 14 | Circumventric- ular organs:a novel site of neural stem cells in the adult brain显示文摘 | Bennett L Yang M Enikolopov G | 2009 | Mol Cell Neurosci2009,41,3: | 1 |
| 15 | UFr-3NaF complex formation and decomposition显示文摘 | Cathers G I Bennett M R Jolley R L | 1958 | Industrial and Engineering Chemistry1958,50,11: | 1 |
| 16 | Triterpenoids, tocotrienols and xanthones from the bark of Cratoxylum cochinchinense 显示文摘 | Bennett G J Harrison L J Sia G | 1993 | Phytochemistry1993,32,5: | 1 |
| 17 | Minor xanthones from the bark of Cratoxylum cochinchinense 显示文摘 | Sia G Bennett G J Harrison L J | 1995 | Phytochemistry1995,38,6: | 1 |
| 18 | Heterotopically transplanted CVO neural stem cells generate neurons and migrate with SVZ cells in the adult mouse brain 显示文摘 | Bennett L B Cai J Enikolopov G | 2010 | Neurosci Lett2010,475,1: | 1 |
| 19 | Heterotopically trans- planted CVO neural stem cells generate neurons and migrate with SVZ cells in the adult mouse brain 显示文摘 | Bennett L B Cai J Enikolopov G | 2010 | Neurosci Lett2010,475,1: | 1 |
| 20 | Mortality in broiler chickson feed amended with Fusarium proliferatum culture material orwith purified fumonisin B1 and moniliformin显示文摘 | Javed T Bennett G A Richard J L | 1993 | Mycopathologia1993,123,: | 1 |