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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 3 | The physical maps for sequencing human chromosomes 1,6,9,10,13,20 and X显示文摘 | Bentley D R Delouk B P Dunham A | 2001 | Nature2001，409，6822： | 1 |
| 4 | Structural basis for the immunogenic properties of the meningococcal vaccine candidate LP2086显示文摘 | MASCIONI A BENTLEY B E CAMARDA R | 2009 | J Biol Chem2009，284，13： | 1 |
| 5 | Glioblastoma-derived tumor cells induce vasculogenic mimicry through flk-I activation 显示文摘 | Francescone R Sculty S Bentley B | 2012 | JBiolChem2012，287，24： | 1 |
| 6 | Arthritic pain is processed in brain areas concerned with emotions and fear 显示文摘 | Kulkami B Bentley DE Etliott R | 2007 | Arthritis Rheum2007，56，： | 1 |
| 7 | The morphology of canines in relation to preadjusted appliances显示文摘 | Germane N Bentley B Isaacson R J | 1990 | Angle Orthod1990，60，1： | 1 |
| 8 | The impact of granular formulations of phorate,terbufos,carbofuran,carbosulfan and thiofanox on newly sown Italian ryegrass (Lolium multiflorum) 显示文摘 | CLEMENTS R O BENTLEY B R JACKSON C A | 1986 | Crop Prot1986，5，6： | 1 |
| 9 | Glioblastoma -derived tumor cells induce vasculogenic mimicry through Flk -1 activation 显示文摘 | Francescone R Scully S Bentley B | 2012 | J Biol Chem2012，287，24： | 1 |
| 10 | A YKL-40-neu- tralizing antibody blocks tumor angiogenesis and progression: potential therapeutic agent in cancev显示文摘 | Faibish M Franceseone R Bentley B | 2011 | Mol Cancer Ther2011，10，5： | 1 |
| 11 | Drilling to the beds of the Greenland and Antarctic ice sheets: a review显示文摘 | BENTLEY C R ROCI B R | 2007 | Annals of Glaciology2007，47，： | 1 |
| 12 | Choice of fluid influences outcome in prolonged hypotensive resuscitation after hemorrhage in awake rats显示文摘 | Handrigan M T Bentley T B Oliver J D Tabaku L S Burge J R Atkins J L | 2005 | Shock2005，23，： | 1 |
| 13 | Electron energy-loss spectroscopic study of the surface of ceria abrasives显示文摘 | GILLISS S R BENTLEY T CARTER C B | 2005 | Applied Surface Science2005，241，12： | 1 |
| 14 | A YKL-40-neu- tralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers显示文摘 | Faibish M Francescone R Bentley B | 2011 | Mol Cancer Ther2011，10，： | 1 |
| 15 | Prolonged inhibition of muscle camitine palmitoyltransferase-1 promotes intramyocelhllar lipid accumulation and insulin resistance in rats 显示文摘 | Dobbins R L Szczepaniak L S Bentley B | 2001 | Diabetes2001，50，1： | 1 |
| 16 | Visceral organ mass and cellularity in growth-restricted and refed beef steers显示文摘 | Sainz R D Bentley B E | 1997 | Anita Sci1997，75，： | 1 |
| 17 | A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers 显示文摘 | Faibish M Francescone R Bentley B | 2011 | Mol Cancer Ther2011，10，5： | 1 |
| 18 | Distinct angiogenic mediators are required for basic fibroblast growth factor- and vascular endothelial growth factor-induced angiogenesis: the role of cytoplasmic tyrosine kinase c-Abl in tumor angiogenesis 显示文摘 | Yah W Bentley B Shao R | 2008 | Mol Biol Cell2008，19，5： | 1 |
| 19 | A YKL-40 neutralizing antibody blocks tumor angio- genesis and progression: a potential therapeutic agent in caneers显示文摘 | Faibish M Franceseone R Bentley B Yan W Shao R | 2011 | Mol Cancer Ther2011，10，： | 1 |
| 20 | Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems显示文摘 | Kulkarni B Bentley DE Elliott R | 2005 | The European Journal Of NeuroScience2005，21，11： | 1 |
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