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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 3 | The physical maps for sequencing human chromosomes 1,6,9,10,13,20 and X显示文摘 | Bentley D R Delouk B P Dunham A | 2001 | Nature2001，409，6822： | 1 |
| 4 | A Quan-tile Regression Approach to Areal Interpolation 显示文摘 | Cromley R G Hanink D M Bentley G C | 2012 | Annals of the Association of American Geo gra -phers2012，102，4： | 1 |
| 5 | The Effect of Machining on the Fatigue Strength of Y -- TiAl Intermetallic Alloy 显示文摘 | Bentley S A Mantle A L Aspinwall D K | 1999 | Intermetallies1999，7，8： | 1 |
| 6 | Dynamic online sensing of sheet modulus of elasticity显示文摘 | Valenzuela M A Bentley J M Lorenz R D | 2010 | IEEE Transactions on Industry Applications2010，46，1： | 1 |
| 7 | Cutis laxa: A review显示文摘 | Berk D R Bentley D D Bayliss S J | 2012 | J Am Acad Dermatol2012，66，5： | 1 |
| 8 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley S D Chater K F Cerdeno-Tarraga A M | 2002 | Nature2002，417，6885： | 1 |
| 9 | Reciprocating Surface Grinding of a Gamma Titanium Aluminide Intermetallic Alloy显示文摘 | Bentley S A Goh N P Aspinwall D K | 2001 | Journal of Materials Processing Technology2001，118，13： | 1 |
| 10 | Human mobility at the early Neolithic settlement of Vaihingen, Germany: evidence from strontium isotope analysis显示文摘 | Bentley R A Krause R Price T D | 2003 | Archaeometry2003，45，： | 1 |
| 11 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley S D Chater K F Cerdeno-Tárraga A M | 2002 | Nature2002，417，： | 1 |
| 12 | The effects of hot boned fat type,preblending treatment and storage time on various physical, processing and sensory char- acteristics of non-specific luncheon loaves 显示文摘 | Bentley D S Reagan J O Miller M F | 1988 | Meat Science1988，23，6： | 1 |
| 13 | Effects of an acute bout of static stretching on 40 m sprint performance: influence of baseline flexibility显示文摘 | FAVERO J P MIDGLEY A W BENTLEY D J | 2009 | Research in Sports Medicine2009，17，1： | 1 |
| 14 | Chemistry for pep- tide and protein PEGylation显示文摘 | Roberts M J Bentley M D Harris J M | 2002 | Adv Drug Deliv Rev2002，54，4： | 1 |
| 15 | Evaluation of the sensitivity and fading characteristics of an image plate system for X-ray diag-nostics显示文摘 | Meadowcroft A L Bentley C D Stott E N | 2008 | Rev Sci Instrum2008，，： | 1 |
| 16 | Com- plete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley S D Chater K F Cerdefio-Tdrraga A M | 2002 | Nature2002，417，6885： | 1 |
| 17 | Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities显示文摘 | DOE C BENTLEY R BEHM D J | 2007 | J Pharmaeol Exp Ther2007，320，1： | 1 |
| 18 | Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘 | Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O | | 0，，： | 1 |
| 19 | Complete genome sequence of the model actinomycete Stretomyces coelicolor A3 ( 2)显示文摘 | Bentley S D Chater K F Cerdeno T | 2002 | Nature2002，，417： | 1 |
| 20 | Volume polarization in reaction field theory显示文摘 | C G Bentley J Chipman D M | 1998 | J Chem Phys1998，108，： | 1 |
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