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| 1 | DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells显示文摘 | Katayama M Kawaguchi T Berger MS Pieper RO | 2007 | 中国神经肿瘤杂志2007，5，4： | 28 |
| 2 | Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy. | Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski | 2007 | World Journal of Gastroenterology2007，13，26： | 4 |
| 3 | Multitarget stool DNA for colorectal cancer screening:A review and commentary on the United States Preventive Services Draft Guidelines显示文摘Multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the Medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an 'alternative' screening test that 'may be useful in select clinical circumstances',despite its very high sensitivity for early stage CRC.The evidence supporting mt-s DNA for routine screening use is robust.The clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing adherence.In a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual adherence.This paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening. | Barry M Berger Bernard Levin Robert J Hilsden | 2016 | World Journal of Gastrointestinal Oncology2016，8，5： | 3 |
| 4 | Automatic adaptive grid refine ment for the euler equations 显示文摘 | Berger M Jameson A | 1985 | AIAA J1985，23，： | 2 |
| 5 | B-type natriuretic peptide predicts sudden death in patients with chronic heart failure显示文摘 | Berger R Huelsman M Strecker K | | 0，，： | 2 |
| 6 | 甘肃齐家文化中仪式性开颅手术初探(英文)显示文摘作为脑外科手术的一种,开颅术在世界多地史前遗址中均有发现。大量发现表明开颅术在颅骨上的尺寸、位置及手术原因千差万别。开颅术在中国境内亦有发现;但在齐家文化(2300-1500BC)遗址中十分少见。位于甘肃省甘南藏族自治区临潭县陈旗乡的磨沟遗址是一处重要的齐家文化墓葬遗址。本文将重点讨论一例磨沟出土的开颅个体,该成年男性个体(M179:R2)颅骨上有愈合程度较高的开颅术的痕迹;同时,将其与其他同时期(3000~0BC)中国出土的开颅术个体进行比较分析,从而论证阐述开颅术实行的原因及过程。该个体左侧顶骨冠状缝后侧位置处有一圆形穿孔,其小孔边缘不甚规则,且有明显愈合痕迹。穿孔切口的特征显示该穿孔由刮削法完成。但由于该穿孔高度愈合,我们无法准确判断完成穿孔所使用的工具。该个体上开颅术的特征以及相关考古学资料使得作者们认为M179:R2进行开颅术的原因或与巫术仪式有关。同时,磨沟出土的其他带有开颅术个体(大多数是男性,且颅骨开颅处愈合程度较高)也支持这一观点。 | Jenna M DITTMAR 詹小雅 Elizabeth BERGER 毛瑞林 王辉 赵永生 叶惠媛 | 2019 | 人类学学报2019，38，3： | 2 |
| 7 | Quantification of derivatives of bisphenol A diglycidyl ether (BADGE) and novolac glycidyl ether(NOGE) migrated from can coatings into tuna by HPLC/fluorescence and MS detection显示文摘 | BERGER U OEHME M GIRARDIN L | 2001 | Fresenius J Anal Chem2001，369，： | 1 |
| 8 | Intracranial microenvironment reveals independent opposing functions of host alphaVbeta3 expression on glioma growth and angiogenesis 显示文摘 | KANAMORI M KAWAGUCHI T BERGER MS | 2006 | J Biol Chem2006，281，37： | 1 |
| 9 | Antiretroviral activity, pharmacokinetics, and tolerability of MK-0518, a novel inhibitor of HIV-I integrase, dosed as monotherapy for 10 days in treatment-naive HIV-1-infected individuals显示文摘 | Dejesus E Berger D Markowitz M | 2006 | J Acquir Immune Defic Syndr2006，43，1： | 1 |
| 10 | A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion显示文摘 | Hansen C L Skordalakes E Berger J M | 2002 | Proc Natl Acad Sci USA2002，99，16： | 1 |
| 11 | Finite element modeling of engagement of rough and wet clutches显示文摘 | F Sadeghi C M Krousgrill | 1996 | Trans of ASME Journal of Tribology1996，118，： | 1 |
| 12 | Lithium ion induced surface reativity change on MgO nanoparticles显示文摘 | BERGER R SCHUH J STERRER M DIWALD O KNOZINGER E | 2007 | J Catalysis2007，247，： | 1 |
| 13 | Vascular damage as a risk factor for benign prostatic hyperplasia and erectile dysfunction显示文摘 | Berger A P Deibl M Leonhartsberger N | 2005 | BJU Int2005，96，7： | 1 |
| 14 | Influence of intraventricular hemorrhage and occlusive hydrocephalus on the long-term outcome of treated patients with basal ganglia hemorrhage:a case-control study显示文摘 | Huttner HB Kohrmann M Berger C | 2006 | J Neurosurg2006，105，3： | 1 |
| 15 | Serological probes for some FMD virus non-structural proteins 显示文摘 | Tesar M Berger H G Marquardt O | 1993 | Virus Genes1993，3，： | 1 |
| 16 | Therapeutic applications of moloclonal antibodies 显示文摘 | Berger M Shankar V Vafai A | 2002 | Am J Med Sci2002，324，1： | 1 |
| 17 | Worldwide perspective of IgA nephropathy显示文摘 | Levy M Berger J | 1988 | Am J Kidney Dis 1988 Nov1988，12，5： | 1 |
| 18 | Evaluation of the consistency of acute physiology and chronic health evaluation (APACHE) scoring in a surgical intensive care unit显示文摘 | Berger M M Marazzi A Fraeman J | 1992 | Crit Care Med1992，20，12： | 1 |
| 19 | Apoptosis -the p53 network显示文摘 | HAUPT S BERGER M | 2003 | J Cell Sci2003，116，20： | 1 |
| 20 | Optimal predictive model selection 显示文摘 | Barbieri M M Berger J O | 2004 | Annals of Statistics2004，32，3： | 1 |
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