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| 1 | 宫颈癌根治术后降低骨髓剂量的调强放疗剂量学研究显示文摘目的通过对宫颈癌根治术后全盆腔常规放疗(CRT)与调强放疗(IMRT)的对比研究,比较应用不同放疗技术在处方剂量45.0、50.4Gy时降低髂骨骨髓受照体积和剂量。方法选择FIGO分期ⅠA~ⅡB期17例宫颈癌根治术后患者,CTV范围包括阴道顶部、宫旁、骶前区域、部分髂总及盆腔淋巴结,CTV外放1cm(后方紧邻直肠后放0.5cm)产生PTV。应用ADAC Pinnacle^3* Version7.4f治疗计划系统分别设计3种照射技术:CRT前后两野对穿(CRT2f)、CRT前后两野+两侧野(CRT4f)、调强7个野(IMRT7f)。处方剂量分别为45.0、50.4Gy,治疗计划优化后确保≥97%PTV接受≥95%处方剂量,应用剂量体积直方图获得不同治疗方法髂骨骨髓的V20、V25、V60、V70。结果处方剂量为45.0Gy时右和左髂骨骨髓IMRT7f、CRT2f,及CRT4f计划的V25分别为45.04%和40.90%、64.37%和65.25%及60.20%和61.42%(H=7.45,P=0.024和H=6.62,P=0.038),V30为36.91%和22.21%、52.69%和48.80%及40.52%和42.33%(H=7.91,P=0.019和H=10.5,P=0.005),V40为23.83%和19。65%、51.85%和46.11%及37.97%和35.30%(H=17.14,P=0.000和H=20.71,P=0.000);处方剂量为50.4Gy时,分别为52.43%和50.06%、65.89%和67.75%及69.56%和64.23%(H=6.29,P=0.043和H=6.37,P=0.041),38.91%和31.93%、54.96%和51.29%及52.18%和47.57%(H=6.91,P=0.031和H=15.19,P=0.000),25.93%和20.87%、53.30%和49.83%及44.26%和37.77%(H=16.71,P=0.000和H=20.78,P=0.000)。结论与CRT相比IMRT技术能产生理想的靶区剂量分布并由此降低髂骨骨髓受照体积和剂量。 | 李慧灵 潘建基 柏朋刚 ZHANG Bin YU Cedric X | 2009 | 中华放射肿瘤学杂志2009，18，3： | 12 |
| 2 | Hepatitis C virus in human B lymphocytes transformed by Epstein-Barr virus in vitro by in situ reverse transcriptase-polymerase chain reaction显示文摘AIM To study persistence and replication ofheltitis C virus (HCV) in patients' peripheralblood mononuclear cells (PBMC) cultured invitro.METHODS Epstein-Barr virus (EBV) was usedto transform the hepatitis C virus from a HCVpositive patient to permanent lymphoblastoidcell lines (LCL). Positive and negative HCV RNAstrands of the cultured cells and growth mediawere detected by reverse transcriptase-polymerase chain reaction ( RT-PCR ) eachmonth. Core and NS5 proteins of HCV werefurther tested using immunohistochemical SPmethod and in situ RT-PCR.RESULTS HCV RNA positive strands wereconsistently detected the cultured cells for oneyear. The negative-strand RNA in LCL cells andthe positive-strand RNA in supernatants wereobserved intermittently. Immunohistochemicalresults medicated expression of HCV NS3 and Cproteins in LCL cytoplasm mostly. The positivesignal of PCR product was dark blue and mainlylocalized to the LCL cytoplasm. The RT-PCRsignal was eliminated by overnight RNasedigestion but not DNase digestion.CONCLUSION HCV may exist and remainfunctional in a cultured cell line for a longperiod. | Ji Lin Cheng Bao Ling Liu Yi Zhang Wen Bin Tong Zheng Yan Bai Fang Feng Institute of Hepatology,Peoples Hospital,Medical Center of Beijing University,Beijing 10(X)44,China | 2001 | World Journal of Gastroenterology2001，7，3： | 11 |
| 3 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 4 | Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow 显示文摘 | Li X Jin H Bin G | 2009 | Experimental Biol Med2009，234，5： | 1 |
| 5 | Anomaly intrusion detection method based on HMM显示文摘 | Y Qiao X W Yin Y Bin | 2002 | Electronics Letters2002，38，13： | 1 |
| 6 | Removal of an encrustation catheter impacted in the prostatic urethra by holmium laser 显示文摘 | Jiatao J Bin X Gusheng T | | Minim Invasive Ther Allied Technol0，20，5： | 1 |
| 7 | 显示文摘 | Jiang X W Bin Y Z Matsuo M | 2005 | Polymer2005，46，： | 1 |
| 8 | Anomaly intrusion detec- tion method based on HMM显示文摘 | QIAO Y XIN X W BIN Y | 2002 | Electronics Letters2002，38，13： | 1 |
| 9 | Genetic diversity and population structure of Yellow Camellia ( Camellia nitidissima) in China as revealed by RAPD and AFLP Markers 显示文摘 | TANG S Q BIN X Y WANG L | 2006 | Biochemical Genetics2006，44，： | 1 |
| 10 | High prevalenee of chronic kidneydisease in population-based patients diagnosed with type 2 diabetes in downtown Shanghai 显示文摘 | Lu Bin Song X I)ong X | 2008 | J Diabetes Complications2008，22，2： | 1 |
| 11 | An understanding of very high cycle fatigue of metals显示文摘 | Marines I Bin X Bathias C | 2003 | International Journal of Fatigue2003，25，： | 1 |
| 12 | Cancer treatment adherence among low-income women with breast or gynecologic cancer: a randomized con- trolled trial of patient navigation 显示文摘 | Ell K Vourlekis B Bin X | 2009 | Cancer2009，115，19： | 1 |
| 13 | Adrenal ganglioneuromas:a 10-year experience in a Chinese population显示文摘 | Qing Y Bin X Jian W | | 0，，： | 1 |
| 14 | Understanding of the geological and geodynamic controls on the formation of the South China Sea:A numerical modeling approach 显示文摘 | Bin Xia Y Zhang X J Cui | 2006 | Journal of Ge odynamics2006，42，： | 1 |
| 15 | Output feedbackadaptive robust preci-sion motion control of linear motors 显示文摘 | Li X Bin Y | 2001 | Automatica2001，45，5： | 1 |
| 16 | Synthesis of LaPO4: Ce,Tb phosphor particles by spray pyrolysis显示文摘 | Wuled L Bin X Hiroaki M | 2001 | Mater Lett2001，50，： | 1 |
| 17 | Genetic diversity and population structure of Yellow Camellia(Camellia nitidissima) in China as revealed by RAPD and AFLP markers显示文摘 | TANG S Q BIN X Y WANG L | 2006 | Biochemical Genetics2006，44，： | 1 |
| 18 | Electrical and Mechani cal Properties of Polyimide-carbon Nanotubes Composites Fabricated by in Situ Polymerization显示文摘 | JIANG X BIN Y MATSUO M | 2005 | Polymer2005，46，18： | 1 |
| 19 | Mitogen-aetivated protein kinase OsMPK6 negatively regulates rice disease resistance to bacterial pathogens 显示文摘 | BIN Y SHEN X L LI X H | 2007 | Planta2007，226，： | 1 |
| 20 | Kinematic analysis of a hybrid serlal-parallel manipulator显示文摘 | X Z Zheng H Z Bin Y G Luo | 2004 | Int J Adv Manuf Technol2004，23，： | 1 |
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