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| 1 | High doses of α-galactosylceramide potentiate experimental autoimmune encephalomyelitis by directly enhancing Th17 response显示文摘伪 - Galactosylceramide (伪 - GC ) 广泛地被知道激活不变的自然漂亮 T (iNKT ) 压制髓磷脂的房间抗原特定的 Th1 回答,保护易受影响的老鼠免于试验性的自体免疫的脑脊髓炎(EAE ) 。这里,我们表明那高加重,而非改善的伪 - GC 开 EAE 的意外发现。当与高剂量的伪 - GC 对待的 MOG35-55-specific T 房间被变成 na 时,类似的结果被观察 ? ve syngeneic 接受者老鼠。进一步的学习证明伪 - GC 的高剂量直接通过 STAT3 的 phosphorylation 和 NF-魏 B 的激活由 CD4+CD44+ 记忆 T 房间的激活提高 Th17 和 Th1 反应。不同于由伪 - GC 的低剂量的 iNKT 房间的激活,伪 - GC 的高剂量直接交往了, CD1d 在 T 房间上表示了并且激活 Th17 和 Th1 房间。而且,介绍抗原的房间(APC ) 主要表示 CD1d1,而 CD4+ T 房间快车 CD1d2 的多数。由 RNAi 的 CD1d1 或 CD1d2 基因表示击倒分别地防碍 iNKT 或 Th17/Th1 房间的激活。因此,伪 - GC 处理能改善或变得更坏由雇佣取决于剂量的 APC 或 Th17/Th1 房间的 EAE 使用了。 | Gaochao Qian Xia Qin Ying Qin Zang Baoxue Ge Taylor B Guo Bing Wan Lei Fang Jingwu Z Zhang | 2010 | Cell Research2010，20，4： | 3 |
| 2 | Electric-field-induced redistribution of polar nano-regions in a relaxor ferroelectric显示文摘 | Xu G Y Zhong Z Bing Y | 2006 | Nature Mater2006，5，2： | 1 |
| 3 | Studies on particle size of waterborne emulsions derived from epoxy resin显示文摘 | Zhang Z Z Huang Y H Bing L | 2001 | Euro Polym J2001，37，： | 1 |
| 4 | Effect of mechanical stretch on the expressions of elastin,LOX and Fibulin-5 in rat BMSCs with ligament fibroblasts co-culture显示文摘 | Bing Z Linlin L Jianguo Y | 2012 | Mol Biol Rep2012，39，5： | 1 |
| 5 | Increased cardiomyocyte apoptosis during the transitionto heart failure in the spontaneously hypertensive rat显示文摘 | Li Z Bing OH Long X | 1997 | Am J Physiol1997，272，： | 1 |
| 6 | Renal epithelioid angiomyolipoma显示文摘 | Bing Z Mac Lennan G T | 2009 | J Urol2009，182，5： | 1 |
| 7 | Physical properties and loading capacity of starch-based microparticles crosslinked with trisodium trime- taphosphate 显示文摘 | Bing Z L Li J W Dong L A | 2009 | Journal of Food Engineering2009，92，： | 1 |
| 8 | Effect of mechanical stretch on theexpressions of elastin,LOX and Fibulin-5 in rat BMSCs with ligament fi-broblasts co-culture显示文摘 | Bing Z Linlin L Jianguo Y et ai | 2012 | Mol Biol Rep2012，39，5： | 1 |
| 9 | A rapid distillation method coupled with ion chromatography for the determination of total sulphur dioxide in foods 显示文摘 | ZHI X Z GONG K L BING HZ | 2012 | Food Chemistry2012，131，3： | 1 |
| 10 | Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat显示文摘 | Li Z Bing OH Long X | 1997 | Am J Physiol1997，272，52： | 1 |
| 11 | Solutions,Algo- rithms and Inter-Relations for Local Minimization Search Geophysical Inversion显示文摘 | Greenhalgh S A Bing Z Green A | 2006 | J Geophys Eng2006，5，： | 1 |
| 12 | PAR-4:a possible new target for age-re- lated disease显示文摘 | Qinan W Ling Z Bing C | 2014 | Expert Opin Ther Targets2014，18，8： | 1 |
| 13 | Syk tyrosine kinase expression during multistep mammary carcinogenesis显示文摘 | Gatalica Z Bing Z | 2005 | Croat Med J2005，46，3： | 1 |
| 14 | Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat显示文摘 | Li Z Bing OH Long X | 1997 | Am J Physiol1997，272，： | 1 |
| 15 | Application of Catalytic Wet Air Oxidation for Treatment of H- acid Manufacturing Process Waste Water 显示文摘 | Zhu W P Bing Y J Li Z H | 2002 | Water Reseaarch2002，，36： | 1 |
| 16 | Expression of a Tri-choderma reesei beta-xylanase gene in Escherichia coli and activity of the enzyme on fiber-bound substrates显示文摘 | Jun H Bing Y Keying Z | 2009 | Protein Expr Purif2009，67，1： | 1 |
| 17 | Increased cardiomyocyte apoptosis during the transition of heart failure in the spontaneously hypertensive rat 显示文摘 | Li Z Bing OHL Long X | 1997 | Am J Physiol1997，272，： | 1 |
| 18 | Effects of Chemical Compositions on the Growth of Relaxor Ferroelectric Pb (SCl/2 Nb1/2 )(1-x) TixO3 Single Crystals 显示文摘 | Bing Y H Ye Z G | 2003 | Journal of Crystal Growth2003，250，12： | 1 |
| 19 | Increased cardiomyocyte apoptotsis during the transition to heart failure in the spontaneously hypertensive rat 显示文摘 | Li Z Bing OHL Long X | 1997 | Am J Physiol1997，272，5： | 1 |
| 20 | p53 in pure epithelioid PE- Coma:an immunohistoehemistry study and gene mutation analysis显示文摘 | Bing Z Yao Y Pasha T | 2012 | Int J Surg Pathol2012，20，2： | 1 |
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