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| 1 | m^6A mRNA methylation sustains Treg suppressive functions显示文摘 | Jiyu Tong Guangchao Cao Ting Zhang Esen Sefik Maria Carolina Amezcua Vesely James P Broughton Shu Zhu Huabin Li Bin Li Lei Chen Howard Y Chang Bing Su Richard A Flavell Hua-Bing Li | 2018 | Cell Research2018，28，2： | 30 |
| 2 | Molecular dynamics simulation and continuum modelling of granular surface flow in rotating drums显示文摘Numerical simulations of granular flows in rotating drums operated at medium to high rates (Fr=0.1― 0.2) have been carried out by using a Molecular Dynamics (MD) algorithm that incorporates inelastic particle interactions, sliding friction and rolling friction. The results indicate that the behavior of granular flow in rotating drums can be classified into two distinct zones: a shear active layer at the bed surface and a quasi-static plug flow region adjacent to the wall. The residence time of a tracer particle in the active layer is approximately a third or a half of that in the plug flow region. The thickness of the active layer at mid-chord is about 0.57―0.61 times that of the plug flow region. It is found that all cases simulated in this work are in the rolling-cascading intermediate regime instead of the pure rolling re-gime. The simulated tangential velocity at the mid-chord is also compared with experimental results reported in the literature and good agreement has been obtained. Based on the MD simulations and experimental results, a continuum approach has also been developed. It is shown that the behavior of granular solids in the plug flow region experiences plastic deformation along the radial direction from the wall with the velocity profiles well described by an exponential function, whereas the active layer velocity follows a simple expression for the Couette shear flow. Discussion has also been made on the granular temperature and concentration profiles. | LI ShuiQing YAO Qiang CHEN Bing ZHANG Xuan DING Y L | 2007 | Chinese Science Bulletin2007，52，5： | 3 |
| 3 | Healing effects of heparin on acetic acid-induced gastric ulcers in rats显示文摘HealingefectsofheparinonaceticacidinducedgastriculcersinratsYangLi,QiBingMeiandChiHinChoDepartmentofPharmacology,FacultyofMe... | Yang Li, Qi Bing Mei and Chi Hin Cho Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 5 Sassoon Road, Hong Kong (Li Y, Mei QB and Cho CH) | 1998 | Chinese Medical Journal1998，，1： | 2 |
| 4 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 5 | Electric-field-induced redistribution of polar nano-regions in a relaxor ferroelectric显示文摘 | Xu G Y Zhong Z Bing Y | 2006 | Nature Mater2006，5，2： | 1 |
| 6 | Elite endurance athletes and ACE I allele the role of genes in athletic performance显示文摘 | George G Bing Y Brett H | 1998 | Hum Genet1998，103，1： | 1 |
| 7 | Studies on particle size of waterborne emulsions derived from epoxy resin显示文摘 | Zhang Z Z Huang Y H Bing L | 2001 | Euro Polym J2001，37，： | 1 |
| 8 | New Condition Assessment Procedure for Asphalt Pavement Layers, Using Failing Weight Deflectometer Deflections 显示文摘 | XU Bing RANJITHAN S R KIM R Y | 2002 | Transportation Research Record2002，1806，： | 1 |
| 9 | Aortic calcification in urolithiasis patients显示文摘 | Yasui T Itoh Y Bing G | 2007 | Scand J Urol Nephrol2007，41，5： | 1 |
| 10 | Purification, cloning, and characterization of the CELI nuclease 显示文摘 | Bing Y Xiao W Nagendra S K | 2003 | Biochemistry2003，39，： | 1 |
| 11 | Effect of mechanical stretch on the expressions of elastin,LOX and Fibulin-5 in rat BMSCs with ligament fibroblasts co-culture显示文摘 | Bing Z Linlin L Jianguo Y | 2012 | Mol Biol Rep2012，39，5： | 1 |
| 12 | Influence of modified wood fibers on the mechanical properties of wood fiber-reinforced polyethylene显示文摘 | Bing L Huang Y H Cong G M | 1997 | Journal of Applied Polymer Science1997，66，： | 1 |
| 13 | Effect of mechanical stretch on theexpressions of elastin,LOX and Fibulin-5 in rat BMSCs with ligament fi-broblasts co-culture显示文摘 | Bing Z Linlin L Jianguo Y et ai | 2012 | Mol Biol Rep2012，39，5： | 1 |
| 14 | 显示文摘 | Zeng Y Qiao L Bing Y F | 2012 | Sens Actuators B2012，173，： | 1 |
| 15 | Zine-alpha2-glyeoprotein, a lipid mobilizing factor,is expressed in adipocytes and is up-regulated in mice with cancer cachexia显示文摘 | Bing C Bao Y Jenkins J | 2004 | Proc Natl Acad Sci USA2004，101，8： | 1 |
| 16 | Seismic performance of strength- ened reinforced concrete beam-column joints using FRP composites 显示文摘 | LI Bing GRACE H Y G | 2009 | Journal of Structural Engineering2009，135，10： | 1 |
| 17 | Antitumor and immunomodulatory activity of Astragalus membranaceus polysaccharides in H22 tumor-bearing mice显示文摘 | BIN Y BING X TAO YS | 2013 | International Journal of Biological Macromolecules2013，62，11： | 1 |
| 18 | Blood-brain barrier(BBB)disruption using a diagnostic ultrasound scanner and Definity in Mice显示文摘 | Bing KF Howles GP Qi Y | 2009 | Ultrasound Med Biol2009，35，8： | 1 |
| 19 | Optimization of parthenogenetic activa- tion and subsequent development of porcine oocytes activated by a com- bined electric pulse and butyrolactone I treatment 显示文摘 | Bing Y Che L Hirao Y | 2003 | J Reprod Dev2003，49，2： | 1 |
| 20 | The possible role of hy- drogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells显示文摘 | Duj HY Chung Y BinG JiangH | 2004 | Heart Vessels2004，，19： | 1 |
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