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| 1 | Kaempferol inhibits the growth and metastasis of cholangiocarcinoma in vitro and in vivo显示文摘Kaempferol 是被报导了在各种各样的恶意的肿瘤展出 antitumor 活动的 flavonoid。然而, cholangiocarcinoma (CCA ) 上的 kaempferol 的角色大部分是未知的。在这篇文章,我们发现 kaempferol 在 vitro 在 HCCC9810 和 QBC939 房间禁止了增长,减少的殖民地形成能力,和导致的 apoptosis。从 transwell 试金和愈合创伤的试金的结果证明 kaempferol 显著地在 vitro 压制了 HCCC9810 和 QBC939 房间的迁居和侵略能力。Kaempferol 被发现 Bcl-2 的表示到减少并且增加 Bax 的表情,船边交货, cleaved-caspase 3, cleaved-caspase 8, cleaved-caspase 9,并且 cleaved-PARP。另外, kaempferol 另外 downregulated phosphorylated AKT, TIMP2,和 MMP2 的层次。在 vivo,这被发现下的异种皮移植的体积(在对待 kaempferol 的组的 0.15 厘米 3) 比那小(在控制组的 0.6 厘米 3) 。Kaempferol 也在肺转移模型压制了转移 foci 的数字和卷,没有鼠标的身体重量上的显著效果。Immunohistochemistry 试金证明 Ki-67-positive 房间的数字在控制组比那在对待 kaempferol 的组是更低的。我们进一步证实在在 vivo 的 kaempferol 处理以后的 apoptosis 相关、侵略相关的蛋白质的变化类似于在 vitro 的结果。这些数据建议 kaempferol 可以是为 CCA 的处理的一个有希望的候选人代理人。 | Youyou Qin Wu Cui Xuewei Yang Baifeng Tong | 2016 | Acta Biochimica et Biophysica Sinica2016，48，3： | 15 |
| 2 | The application of back-scattered electron imaging for characterization of pearlitic steels显示文摘The microstructures of pearlitic steel wire rods and steel wires are commonly characterized by secondary electron imaging (SEI)technique using scanning electron microscopy(SEM).In this work,a back-scattered electron imaging(BSEI)method is proposed to determine the microstructures of undeformed and deformed pearlitic steels with nanometer scale pearlite lamellae.The results indicate that BSEI technique can characterize the pearlite lamellas veritably and is effective in quantitative measurement of the mean size of pearlite interlamellar spacing.To some extent,BSEI method is more suitable than SEI technique for studying undeformed and not severely deformed pearlitic steels. | GUO Ning LIU Qing XIN YunChang LUAN BaiFeng ZHOU Zheng | 2011 | Science China(Technological Sciences)2011，54，9： | 9 |
| 3 | Electron backscatter diffraction investigation of duplex-phase microstructure in a forged Zr-2.5Nb alloy显示文摘Microstructural features of a duplex-phase Zr-2.5Nb alloy were investigated in detail using electron channeling contrast(ECC)imaging and electron backscatter diffraction(EBSD)technique in an emission gun scanning electron microscope(FEGSEM).The excellent resolution provided by the FEGSEM promises the combined utilization of both techniques to be quite adequate for characterizing the duplex-phase microstructures.Results show that the microstructure of the Zr-2.5Nb alloy is composed of bulkαgrains(majority)in equiaxed or plate shape and thinβfilms(minority)surrounding the bulk grains,with their average grain size and thickness measured to be 1.4μm and 72 nm,respectively.Analyses onα-grain boundaries reveal a number of low angle boundaries,most of which belong to deformation-induced dislocation boundaries.Measurements on relative proportions of various Burgers boundaries suggest very weak(if any)variant selection duringβ→αcooling,which should be related to deformation-induced higher nucleation rate ofαphases.Compared to earlier attempts,more satisfactory indexing of fineβphases(down to nanoscale)is attained by the FEGSEM-based EBSD.Examples are presented to clearly reveal well-obeyed Burgers orientation relationships between adjacentαandβphases.Finally,it is deduced that continuing application of the FEGSEM-based EBSD to duplex-phase Zr alloys could help clarify controversies like the deformation priority of the two phases. | CHAI LinJiang WANG ShuYan LUAN BaiFeng LIU Qing | 2016 | Science China(Technological Sciences)2016，59，4： | 5 |
| 4 | Effect of cooling rate on β→α transformation during quenching of a Zr-0.85Sn-0.4Nb-0.4Fe-0.1Cr-0.05Cu alloy显示文摘The effect of β→α cooling rate during quenching on a new Zr-Sn-Nb-Fe-Cr-Cu alloy is reported.The microstructure evolution is well characterized by electron channeling contrast(ECC) imaging and transmission electron microscopy(TEM) techniques.The results show that specimens cooled by water,liquid nitrogen,air and furnace from β-phase present martensitic,coarse basket-weave,parallel-plate and lenticular structure,respectively.Residual β phase is detected by performing electron diffraction and composition analysis in the furnace cooled specimen.Micro hardness values of specimens decrease while the width of α laths increase with the cooling rate decreasing.The preliminarily established quantitative relationship among the cooling rate,microstructure and mechanical properties will shed light on the microstructure control and property optimization. | CHAI LinJiang LUAN BaiFeng CHEN JianWei ZHOU Jun LIU Qing | 2012 | Science China(Technological Sciences)2012，55，10： | 5 |
| 5 | Ecological Consequences of Elevated CO2 and Bt Cotton on Soil Collembola显示文摘 | Liang Chang Baifeng Wang Xianghui Liu Feng Ge | 2013 | Journal of Agricultural Science and Technology(A)2013，3，9： | 5 |
| 6 | Microstructure and texture evolution in fully pearlitic steel during wire drawing显示文摘The evolution of morphology of pearlite and crystallographic texture of ferrite matrix in fully pearlitic steels during wire drawing were quantitatively investigated.The study revealed that a fiber structure of the pearlite morphology and a <110> fiber texture of the ferrite matrix begin to take shape and develop gradually with increasing strain.The growth rates of the fiber structure and the <110> texture are different in different regions within the wires with increasing drawing strain.There is a close relationship between the pearlite morphology and the crystalline texture during wire drawing.The pearlite interlamellar spacing(ILS) and thickness of cementite lamellae(T) decrease gradually both in longitudinal and transverse sections.The definition of pearlite colony should be reconsidered for describing microstructure of the wire drawing deformed pearlitic steels. | GUO Ning LUAN BaiFeng WANG BingShu LIU Qing | 2013 | Science China(Technological Sciences)2013，56，5： | 5 |
| 7 | Microstructural characteristics of cold-rolled Zr-2.5Nb alloy annealed near the monotectoid temperature显示文摘A dual-phase Zr-2.5 Nb alloy was rolled at room temperature to 50% reduction and then annealed at two temperatures(560 and580°C) near the monotectoid temperature. X-ray diffraction, electron channeling contrast imaging and electron backscatter diffraction techniques were jointly used to characterize microstructural characteristics developed in the as-rolled and annealed specimens. Results show that plastic deformation occurs in both bulk α-Zr grains and thin β-Zr films during rolling, allowing large lattice strains to be accumulated in β-Zr and active dislocation slip(especially the prismatic áa?slip) to be initiated in α-Zr. During subsequent annealing at 580°C, the prior β-Zr films are transformed into submicron β-Zr particles, which lose coherency(the Burgers orientation relationship) with surrounding α grains. In the specimen annealed at 560°C, however, the prior β-Zr films are found to be decomposed into nanoscale β-Nb particles. In both the annealed specimens, the β-Zr and the β-Nb particles appeared to be linearly distributed along the rolling direction. Two types of α structures, i.e., small equiaxed crystallites formed by recovery of dislocation structures and coarse bamboo-like recrystallized grains, are revealed in the annealed specimens. Effective boundary pinning due to the dense β-phase particles is demonstrated to play a key role in forming such unusual bamboo-like grains. | CHAI LinJiang WU Hao WANG ShuYan LUAN BaiFeng WU Yue HUANG XiaoYu | 2018 | Science China(Technological Sciences)2018，61，4： | 3 |
| 8 | Deformation bands in fully pearlitic steel during wire drawing显示文摘The deformation of fully pearlitic steels during wire drawing has been investigated for both longitudinal section and transverse section by back-scattered electron imaging(BSEI),electron back-scattered diffraction(EBSD),and transmission electron microscope(TEM).The results show that a large number of deformation bands(DBs)composed of a mixture of kink-like bands and shear-like bands were observed both in the longitudinal section and the traverse section of the drawn wires.The formation of such bands involves two aspects:heterogeneous deformation in the scale of pearlite colonies and instability of ferrite-cementite interfaces due to stress concentration during wire drawing.The development of such bands in fully pearlitic steels dominates the formation of metallographic texture,reduces the pearlite interlamellar spacing and promotes the development of<110>fiber crystalline texture of ferrite matrix during wire drawing. | GUO Ning SONG Bo LUAN BaiFeng CHEN ZhiQian LIU Qing | 2014 | Science China(Technological Sciences)2014，57，4： | 2 |
| 9 | Novel Software Automated Testing System Based on J2EE显示文摘 | Songwen Pei Baifeng Wu Kun Zhu Qiang Yu | 2007 | Tsinghua Science & Technology2007，，： | 1 |
| 10 | Effect of Transgenic Corn Cultivation and Sampling Location on Feeding Habits of Collembola显示文摘 | Baifeng Wang Liang Chang Donghui Wu Xinyuan Song | 2014 | Journal of Agricultural Science and Technology(A)2014，4，3： | 1 |
| 11 | Novel Software Automated Testing System Based on J2EE显示文摘 | PEI Songwen WU Baifeng | 2007 | TSING HUA SCIENCE AND TECHNOLOGY2007，，： | 1 |
| 12 | Novel Software Automated Testing System Based on J2EE显示文摘 | PEI Songwen WU Baifeng ZHU Kun | 2007 | Tsinghua Science and Technology2007，12，1： | 1 |
| 13 | Facile preparation of amperometric laccase biosensor with multifunction based on the matrix of carbon nanotubes-chitosan composite显示文摘 | LIU Ying QU Xiaohu DONG Shaojun GUO Hongwei CHEN Hongjun LIU Baifeng | 2006 | Biosens Bioelectron2006，21，12： | 1 |
| 14 | A simple route to incorporate redox mediator into carbon nanotubes/Nafion composite film and its application to determine NADH at low potential显示文摘 | Minghua Huang Heqing Jiang Junfeng Zhai Baifeng Liu Shaojun Dong | 2007 | Talanta2007，，1： | 1 |
| 15 | Concurrent inheritance of microstructure and texture after slow β→α cooling of commercially pure Zr显示文摘A rolled and recrystallized commercially pure Zr sheet was β-solution treated and then cooled at two rates, i.e. air cooling(AC)and furnace cooling(FC). Microstructures and textures of original and β-cooled specimens were characterized by use of electron channeling contrast imaging, electron backscatter diffraction and X-ray diffraction techniques. Results reveal a novel phenomenon, i.e. the concurrent inheritance of microstructure and texture in the FC specimen cooled at a very slow rate. In contrast, for the AC specimen with faster cooling, typical lamellar α phases are obtained with relatively scattered texture.Based on comparatively crystallographic and thermodynamic analyses, reasons accounting for microstructure and texture differences in both cases are discussed, highlighting the significant role played by the variant selection behavior. It is postulated that increasing cooling rates should be more feasible to change the transformed texture in Zr materials. | CHAI LinJiang LUAN BaiFeng CHEN BaoFeng YANG HuiLong LIU Qing HUANG WeiJiu | 2016 | Science China(Technological Sciences)2016，59，11： | 1 |
| 16 | Electrochemical behavior of redox species at carbon fibre microdisk array electrode modified with mixedvalent molybdenum(Ⅵ, Ⅴ) oxide显示文摘 | Liu Shaoqin Wang Baoxing Liu Baifeng | 2000 | Electrochimica Acta2000，45，10： | 1 |
| 17 | Covalent modifica- tion of a glassy carbon surface by 4-aminobenzoic acid and its application in fabrication of a polyoxometalates-consistingmonolayer and multilayer films 显示文摘 | Liu Jianyun Cheng Long Liu Baifeng | 2000 | Langmuir2000，16，19： | 1 |
| 18 | Effect of grain size on α-variant selection in a ZrTiAlV alloy显示文摘Local crystallographic orientation characteristics of grains with different sizes in a ZrTiAlValloy after interrupted cooling from βphase region are investigated by electron backscatter diffraction(EBSD) technique. A statistical analysis of EBSD data shows that bigger parent β grains present weaker variant selection than smaller grains. The relevant influences are studied by comparing the nucleation behavior of grain boundary α(GBα) and succedent growth stage in varisized grains. In-depth analysis indicates that the deviation between pole of GBα and common pole of adjacent parent β grains is responsible for the smaller degree of variant selection inside the bigger parent β grains. The formation of more than one GBα type at the β/β grain boundary with common pole in bigger grains results in obstructing each other for these variants during the following growth stage, while only one type of GBα nucleate at the β/β grain boundary with common pole in smaller grains and it can freely grow into the interior of the grains, leading to stronger variant selection in smaller β grains. | LI FeiTao QIU Xi LIAO ZhongNi LUAN BaiFeng ZHANG XinYu LIU RiPing LIU Qing | 2019 | Science China(Technological Sciences)2019，62，6： | 1 |
| 19 | Recovery of Collembola in Pinus tabulaeformis Plantations显示文摘Large areas of forest plantations have been developed in China.It is important to evaluate the soil fauna in plantations and the conditions needed for their recovery in view of the large areas of plantations in China.Three Pinus tabulaeformis forests,a 26-year-old plantation(P26) and a 45-year-old plantation(P45),exposed to clear-cutting before plantation,and an 80-260-year-old natural forest(N260),were chosen to study the effects of different forest ages/types on Collembola community in the litter and soil layers during2008 and 2009.Soil conditions in P26 and P45 were significantly deteriorated when compared to N260.A higher value of soil bulk density and lower values of soil organic matter,soil N,litter depth,soil pH,and soil water content were observed in P26 and P45.Totally,the same genera of Collembola tended to occur in the forests of all ages studied;however,the Collembola community structure was significantly impacted by the differences in forest age.Both in the litter and soil layers,the density and generic richness of the Collembola were the highest in N260 and the lowest in P26.Some collembolan groups were sensitive to soil conditions in particular forest ages.N260 was associated with relatively high abundance of Plutomurus collembolans and P45 with relatively high abundance of Pseudofolsomia collembolans.The canonical correspondence analysis showed that the community structure of Collembola was mainly affected by forest age in both litter and soil layer.The ordination analysis of non-metric multidimensional scaling also found that the Collembola community did not recover to the level of natural forests in 26-year regeneration after clear-cutting.Even in 45-year regeneration after clear-cutting,the Collembola community only showed a slight recovery to the level of natural forests.Our results clearly showed that both Collembola community and soil conditions did not recover in 26- and 45-year regeneration after clear-cutting in P.tabulaeformis plantations;however,they might have the potential to recover in the future because the same genera of Collembola were distributed in the plantations and natural forests. | CHANG Liang WANG Baifeng LIU Xianghui Mac A.CALLAHAM Jr. GE Feng | 2017 | Pedosphere2017，27，1： | 1 |
| 20 | Influence of pre-torsion deformation on microstructures and properties of cold drawing pearlitic steel wires显示文摘 | Ning Guo Baifeng Luan Qing Liu | 2013 | Materials and Design2013，，： | 1 |
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