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| 1 | Turbulent Convective Heat Transfer of Methane at Supercritical Pressure in a Helical Coiled Tube显示文摘The heat transfer of methane at supercritical pressure in a helically coiled tube was numerically investigated using the Reynolds Stress Model under constant wall temperature. The effects of mass flux(G), inlet pressure(P_(in)) and buoyancy force on the heat transfer behaviors were discussed in detail. Results show that the light fluid with higher temperature appears near the inner wall of the helically coiled tube. When the bulk temperature is less than or approach to the pseudocritical temperature(T_(pc)), the combined effects of buoyancy force and centrifugal force make heavy fluid with lower temperature appear near the outer-right of the helically coiled tube. Beyond the T_(pc), the heavy fluid with lower temperature moves from the outer-right region to the outer region owing to the centrifugal force. The buoyancy force caused by density variation, which can be characterized by Gr/Re^2 and Gr/Re^2.7, enhances the heat transfer coefficient(h) when the bulk temperature is less than or near the T_(pc), and the h experiences oscillation due to the buoyancy force. The oscillation is reduced progressively with the increase of G. Moreover, h reaches its peak value near the T_(pc). Higher G could improve the heat transfer performance in the whole temperature range. The peak value of h depends on P_(in). A new correlation was proposed for methane at supercritical pressure convective heat transfer in the helical tube, which shows a good agreement with the present simulated results. | WANG Chenggang SUN Baokun LIN Wei HE Fan YOU Yingqiang YU Jiuyang | 2018 | Journal of Thermal Science2018，27，1： | 5 |
| 2 | Increasing the greenness of an organic acid through deep eutectic solvation and further polymerisation显示文摘Acrylic acid(AA)is an important and widely used industrial chemical,but its high toxicity renders its use incompatible with the concept of green development.By leveraging its terminal carboxyl group and unsaturated bond,we designed and explored a new strategy to increase the greenness of AA via its eutectic melting using a quaternary ammonium salt(choline chloride)to form a deep eutectic solvent(DES),followed by polymerisation of the DES to form a polymer(poly(DES)).The greenness of AA,DES,and poly(DES)was evaluated via an in vitro test using MGC80-3 cells and an in vivo test using Kunming mice.The toxicity improved from Grade 2(moderately toxic)for AA to Grade 1(slightly toxic)for DESs and Grade 0(non-toxic)for poly(DES)in the in vitro test.Moreover,the poly(DES)s showed a lower toxicity in mice than the DESs in the in vivo test.Thus,greenness enhancement was successfully achieved,with the greenness following the order AA | Liteng Li Xiaofang Li Susu Zhang Hongyuan Yan Xiaoqiang Qiao Hongyan He Tao Zhu Baokun Tang | 2022 | Green Energy & Environment2022，7，4： | 0 |
| 3 | Corrigendum to “Increasing the greenness of an organic acid through deep eutectic solvation and further polymerisation” [Green Energy & Environ 7 (4) (August 2022) 840–853]显示文摘The authors regret that the name of the ethic committee that approved the study and the reference number was omitted from the published paper.In this research,all animal experiments were performed in accordance with the Guide for the Care and Use of Laboratory Animals(US National Institutes of Healh)and were approved by the Animal Welfare and Ethical Committee of Hebei University(No.IACUC-2020XG021,Baoding,China). | Liteng Li Xiaofang Li Susu Zhang Hongyuan Yan Xiaoqiang Qiao Hongyan He Tao Zhu Baokun Tang | 2024 | Green Energy & Environment2024，9，3： | 0 |
| 4 | Inosine:A broad-spectrum anti-inflammatory against SARS-CoV-2 infection-induced acute lung injury via suppressing TBK1 phosphorylation显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-induced cytokine storms constitute the primary cause of coronavirus disease 19(COVID-19)progression,severity,criticality,and death.Glucocorticoid and anti-cytokine therapies are frequently administered to treat COVID-19,but have limited clinical efficacy in severe and critical cases.Nevertheless,the weaknesses of these treatment modalities have prompted the development of anti-inflammatory therapy against this infection.We found that the broad-spectrum anti-inflammatory agent inosine downregulated proinflammatory interleukin(IL)-6,upregulated anti-inflammatory IL-10,and ameliorated acute inflammatory lung injury caused by multiple infectious agents.Inosine significantly improved survival in mice infected with SARS-CoV-2.It indirectly impeded TANK-binding kinase 1(TBK1)phosphorylation by binding stimulator of interferon genes(STING)and glycogen synthase kinase-3β(GSK3β),inhibited the activation and nuclear translocation of the downstream transcription factors interferon regulatory factor(IRF3)and nuclear factor kappa B(NF-κB),and downregulated IL-6 in the sera and lung tissues of mice infected with lipopolysaccharide(LPS),H1N1,or SARS-CoV-2.Thus,inosine administration is feasible for clinical anti-inflammatory therapy against severe and critical COVID-19.Moreover,targeting TBK1 is a promising strategy for inhibiting cytokine storms and mitigating acute inflammatory lung injury induced by SARS-CoV-2 and other infectious agents. | Ningning Wang Entao Li Huifang Deng Lanxin Yue Lei Zhou Rina Su Baokun He Chengcai Lai Gaofu Li Yuwei Gao Wei Zhou Yue Gao | 2023 | Journal of Pharmaceutical Analysis2023，13，1： | 0 |
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