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| 1 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 2 | Chemiluminescence of Anodized and Etched Silicon:Evidence for a luminescent Siloxene-Like Layer on Porous Silicon显示文摘 | McCord P Yau S L Bard A J | 1992 | Science1992，257，5066： | 1 |
| 3 | Heterogenerous photoeatalytic oxida- tion of cyanide and sulfite in aqueous solutions at semiconductor powder显示文摘 | Nfrank S N Bard A J | 1977 | J Phys Chem1977，81，： | 1 |
| 4 | Algorithms for parallelmachine scheduling: a case study of the tracking and data relay satellite system显示文摘 | Rojanasoonthon S Bard J F Reddy S D | 2003 | Journal of Operational Research Society2003，54，8： | 1 |
| 5 | Variations of oxygenminimum and primary productivity recorded in sediments of the Arabian Sea显示文摘 | SCHULTE S ROSTEK F BARD E | 1999 | Earth and Planerary Science Letters1999，173，： | 1 |
| 6 | Novel carbon-doped TiO2 nanotube arrays with high aspect ratios for efficient solar water splitting 显示文摘 | PARK J KIM H S BARD A J | 2006 | Nano Lett2006，6，： | 1 |
| 7 | 显示文摘 | Park J H Kim S Bard A J | 2006 | Nanoletters2006，6，1： | 1 |
| 8 | Evaluation and prediction of the degradation of a cots CCD induced by displacement damage 显示文摘 | Germanicus R Barde S Dusseau L | 2002 | IEEE trans nucl sci2002，49，6： | 1 |
| 9 | Heterogeneous photocatalytic oxidation of cyanide ion in aqueous solutions at titanium dioxide pow- der显示文摘 | Frank S N Bard A J | 1977 | Journal of the American Chemical Society1977，99，1： | 1 |
| 10 | Langrnuir显示文摘 | Obeng Y S Bard A J | 1991 | 7 : 1951991，7，： | 1 |
| 11 | 显示文摘 | Frank S N Bard A J | 1977 | Journal of Physical Chemistry1977，81，15： | 1 |
| 12 | Chemiluminescence of Anodized and Etched Silicon:?vidence for a Luminescent siloxene-Iike Layer onPorous Silicon 显示文摘 | Mccord P Yau S L Bard A J | 1992 | Science1992，257，： | 1 |
| 13 | Quality Assessment of Cartographic Generalization显示文摘 | Bard S | | 0，，01： | 1 |
| 14 | 显示文摘 | Frank S T Bard A J | 1977 | J Am Chem Soc1977，99，： | 1 |
| 15 | Ionic conductivity in polypyrrole poly(vinyl acetate) films synthesized by chemical oxidative polymerization method 显示文摘 | Barde W S Pakade S V Yawale S P | 2007 | Journal of Non-Crystalline Solids2007，353，： | 1 |
| 16 | Heterogeneous photocatalytic oxidation of cyanide ion in aqueous solutions attihanium dioxide powder显示文摘 | Bard A J | 1977 | Journal of the American Chemical Society1977，99，2： | 1 |
| 17 | Gontrolled Nanofabrication of Highly Oriented Pyrolytic Graphite with the Scanning Tunneling Microscope 显示文摘 | ROBIN L M HENDRIGKS S A BARD A J | 1992 | J Phys Chem1992，96，10： | 1 |
| 18 | Heterogeneous photocatalytic oxidation of cyanide and sulfite in aqueous solutions at semiconductor powders显示文摘 | Frank S N Bard A J | 1977 | J Phys Chem1977，81，15： | 1 |
| 19 | Algorithms for parallel machine scheduling: a case study of the tracking and data relay satellite system 显示文摘 | ROIANASOONTHON S BARD J F REDDY S D | 2003 | Journal of the Operational Research Society2003，54，8： | 1 |
| 20 | Heterogeneous photocatalytic oxidation of cyanide ion in aqueoussolution at TiO2 power显示文摘 | Frank S N Bard A J | 1997 | J Am Chem Soc1997，99，： | 1 |
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