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| 1 | Impact of new treatment options for hepatitis c virus infection in liver transplantation显示文摘Liver transplant candidates and recipients with hepatitis C virus(HCV)-related liver disease greatly benefit from an effective antiviral therapy. The achievement of a sustained virological response before transplantation can prevent the recurrence of post-transplant HCV disease that occurs universally and correlates with enhanced progression to graft cirrhosis. Previous standard-of-care regimens(e.g.,pegylated-interferon plus ribavirin with or without first generation protease inhibitors,boceprevir and telaprevir) displayed suboptimal results and poor tolerance in liver transplant recipients. A new class of potent direct-acting antiviral agents(DAA) characterized by all-oral regimens with minimal side effects has been approved and included in the recent guidelines for the treatment of liver transplant recipients with recurrent HCV disease. Association of sofosbuvir with ribavirin and/or ledipasvir is recommended in liver transplant recipients and patients with decompensated cirrhosis. Other regimens include simeprevir,daclatasvir,and combination of other DAA. Possible interactions should be monitored,especially in coinfected human immunodeficiency virus/HCV patients receiving antiretrovirals. | Elda Righi Angela Londero Alessia Carnelutti Umberto Baccarani Matteo Bassetti | 2015 | World Journal of Gastroenterology2015，21，38： | 3 |
| 2 | 散发型克罗伊茨费尔特-雅各布病患者的睡眠-觉醒紊乱显示文摘Background: The prevalence and characteristics of sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease (sCJD) are poorly understood. Methods: Seven consecutive patients with definite sCJD underwent a systematic assessment of sleep-wake disturbances, including clinical history, videopolysomnography, and actigraphy. Extent and distribution of neurodegeneration was estimated by brain autopsy in six patients. Western blot analyses enabling classification and quantification of the protease-resistant isoform of the prion protein, PrPSc, in thalamus and occipital cortex was available in four patients. Results: Sleep-wake symptoms were observed in all patients, and were prominent in four of them. All patients had severe sleep EEG abnormalities with loss of sleep spindles, very low sleep efficiency, and virtual absence of REM sleep. The correlation between different methods to assess sleep-wake functions (history, polysomnography, actigraphy, videography) was generally poor. Brain autopsy revealed prominent changes in cortical areas, but only mild changes in the thalamus. No mutation of the PRNP gene was found. Conclusions: This study demonstrates in sporadic Creutzfeldt-Jakob disease, first, the existence of sleep-wake disturbances similar to those reported in fatal familial insomnia in the absence of prominent and isolated thalamic neuronal loss, and second, the need of a multimodal approach for the unambiguous assessment of sleep-wake functions in these patients. | Landolt H.-P Glatzel M. Blttler T. C.L. Bassetti 张嘉靖 | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，9： | 2 |
| 3 | Utility of Absolute and Relative Changes in Cardiac Troponin Concentrations in the Early Diagnosis of Acute Myocardial Infarction显示文摘 | Tobias Reichlin Affan Irfan Raphael Twerenbold Miriam Reiter Willibald Hochholzer Hanna Burkhalter Stefano Bassetti Stephan Steuer Katrin Winkler Federico Peter Julia Meissner Philip Haaf Mihael Potocki Beatrice Drexler Stefan Osswald Christian Mueller | 2011 | Circulation2011，，2： | 2 |
| 4 | Colistin and Rifampicin Compared With Colistin Alone for the Treatment of Serious Infections Due to Extensively Drug-Resistant Acinetobacter baumannii: A Multicenter, Randomized Clinical Trial显示文摘 | Emanuele Durante-Mangoni Giuseppe Signoriello Roberto Andini Annunziata Mattei Maria De Cristoforo Patrizia Murino Matteo Bassetti Paolo Malacarne Nicola Petrosillo Nicola Galdieri Paola Mocavero Antonio Corcione Claudio Viscoli Raffaele Zarrilli Ciro Gal | 2013 | Clinical Infectious Diseases2013，，3： | 2 |
| 5 | Sleep and stroke显示文摘 | Bassetti C | 2005 | Seminars Neurol2005，25，1： | 1 |
| 6 | Multiple acute infarcts in the posterior circulation显示文摘 | Bernasconi A Bogousslavsky J Bassetti C | 1996 | J Neurol Neurosurg Psychiatry1996，60，： | 1 |
| 7 | Fast contrast-enhanced MR whole-brain venography显示文摘 | ovblad KO Schneider J Bassetti C | 2002 | Neuroradiology2002，44，8： | 1 |
| 8 | New treatment options a gainst gram-negative organisms显示文摘 | Bassetti M Ginocchio F Mikulska M | 2011 | Crit Care2011，15，2： | 1 |
| 9 | Water deficit affects receptivity of maize silks显示文摘 | Bassetti P Westgate M E | 1993 | Crop Science1993，33，2： | 1 |
| 10 | Sleep and stroke显示文摘 | Bassetti CL | 2005 | Semin Neurol2005，25，： | 1 |
| 11 | Senescence and receptivity of ma- ize silks显示文摘 | Bassetti P Westgate M E | 1993 | Crop Science1993，33，2： | 1 |
| 12 | Colistin and rifampiein in the treatment of multidrug - resistant Acinetobacter baumannii infections显示文摘 | Bassetti M Repetto E Righi E | 2008 | J Antimicrob Chemother2008，61，2： | 1 |
| 13 | Hypersonmia following paramedian thalamic stroke, a report of 12 patients显示文摘 | Bassetti C Mathis J Gugger M | 1996 | Ann Neurol1996，39，： | 1 |
| 14 | Colistin and rifampicin in the treatment of multidrug-resistant Acinetobacter bauman?nii infections显示文摘 | Bassetti M Repetto E Righi E | 2008 | J Antimicrob Chemother2008，6，2： | 1 |
| 15 | Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular- regulated kinase-1/-2 显示文摘 | Kilic ii Bassetti C L Kilic E | 2005 | Neuroscience2005，134，： | 1 |
| 16 | Staphylococcus aureus Infections in Injection Drug Users: Risk Factors and Prevention Strategies显示文摘 | S. Bassetti M. Battegay | 2004 | Infection2004，，3： | 1 |
| 17 | Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae: Importance of Combination Therapy显示文摘 | Mario Tumbarello Pierluigi Viale Claudio Viscoli Enrico Maria Trecarichi Fabio Tumietto Anna Marchese Teresa Spanu Simone Ambretti Francesca Ginocchio Francesco Cristini Angela Raffaella Losito Sara Tedeschi Roberto Cauda Matteo Bassetti | 2012 | Clinical Infectious Diseases2012，，7： | 1 |
| 18 | Sleep abnormalities in hemisheric stroke显示文摘 | Bassetti C Aldrich MS Quint D | 1997 | Sleep Research1997，26，： | 1 |
| 19 | Fast contrast-enhanced MR whole-brain venography 显示文摘 | Lovblad KO Schneider J Bassetti C | 2002 | Neuroradiology2002，44，8： | 1 |
| 20 | Effect of lamotrigine onEEG paroxysmal abnormalities and background activity:a computer-ized analysis显示文摘 | Marcini MG Spanedda F Bassetti MA | 1996 | Br J Clin Pharmacol1996，42，5： | 1 |
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