| 1 | The global and regional prevalence of hepatitis C and B co-infections among prisoners living with HIV:a systematic review and meta-analysis显示文摘Background Hepatitis B virus(HBV)and hepatitis C virus(HCV)infections are common among individuals with human immune deficiency virus(HIV)infection worldwide.In this study,we did a systematic review and meta-analysis of the published literature to estimate the global and regional prevalence of HCV,HBV and HIV coinfections among HIV-positive prisoners.Methods We searched PubMed via MEDLINE,Embase,the Cochrane Library,SCOPUS,and Web of science(ISI)to identify studies that reported the prevalence of HBV and HCV among prisoners living with HIV.We used an eight-item checklist for critically appraisal studies of prevalence/incidence of a health problem to assess the quality of publications in the included 48 cross-sectional and 4 cohort studies.We used random-effect models and meta-regression for the meta-analysis of the results of the included studies.Results The number of the included studies were 50 for HCV-HIV,and 23 for HBV-HIV co-infections.The pooled prevalence rates of the coinfections were 12%[95%confidence interval(CI)9.0–16.0]for HBV-HIV and 62%(95%CI 53.0–71.0)for HCV-HIV.Among HIV-positive prisoners who reported drug injection,the prevalence of HBV increased to 15%(95%CI 5.0–23.0),and the HCV prevalence increased to 78%(95%CI 51.0–100).The prevalence of HBV-HIV coinfection among prisoners ranged from 3%in the East Mediterranean region to 27%in the American region.Also,the prevalence of HCV-HIV coinfections among prisoners ranged from 6%in Europe to 98%in the East Mediterranean regions.Conclusions Our findings suggested that the high prevalence of HBV and HCV co-infection among HIV-positive prisoners,particularly among those with a history of drug injection,varies significantly across the globe.The results of Meta-regression analysis showed a sliding increase in the prevalence of the studied co-infections among prisoners over the past decades,rising a call for better screening and treatment programs targeting this high-risk population.To prevent the above coinfections among prisoners,aimed public health services(e.g.harm reduction via access to clean needles),human rights,equity,and ethics are to be seriously delivered or practiced in prisons. | Hasan Ahmadi Gharaei Mohammad Fararouei Ali Mirzazadeh Golnaz Sharifnia Marzieh Rohani-Rasaf Dariush Bastam Jamileh Rahimi Mostafa kouhestani Shahab Rezaian Mostafa Dianatinasab | 2021 | Infectious Diseases of Poverty2021，10，4： | 1 |
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