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| 1 | Arabidopsis ABF3 and ABF4 Transcription Factors Act with the NF-YC Complex to Regulate SOC1 Expression and Mediate Drought-Accelerated Flowering显示文摘The drought-escape response accelerates flowering in response to drought stress, allowing plants to adaptively shorten their life cycles. Abscisic acid (ABA) mediates plant responses to drought, but the role of ABA-responsive element (ABRE)-binding factors (ABFs) in the drought-escape response is poorly understood. Here, we show that Arabidopsis thaliana ABF3 and ABF4 regulate flowering in response to drought through transcriptional regulation of the floral integrator SUPPRESSOR OF OVEREXPRESSION OF CONSTANS1 (SOC1). The abf3 abf4 mutant displayed ABA-insensitive late flowering under long-day conditions. Ectopic expression of ABF3 or ABF4 in the vasculature, but not in the shoot apex, induced early flowering, whereas expression of ABF3 fused with the SRDX transcript!onal repressor domain delayed flowering. We identified SOC1 as a direct downstream target of ABF3/4, and found that SOC1 mRNA levels were lower in abf3 abf4 than in wild-type plants. Moreover, induction of SOC1 by ABA was hampered in abf3 abf4 mutants. ABF3 and ABF4 were enriched at the -1028- to -657-bp region of the SOC1 promoter, which does not contain canonical ABF-ABRE-binding motifs but has the NF-Y binding element. We found that ABF3 and ABF4 interact with nuclear factor Y subunit C (NF-YC) 3/4/9 in vitro and in planta, and induction of SOC1 by ABA was hampered in nf-yc3 yc4 yc9 mutants. Interestingly, the abf3 abf4, nf-yc3 yc4 yc9, and sod mutants displayed a reduced drought-escape response. Taken together, these results suggest that ABF3 and ABF4 act with NF-YCs to promote flowering by inducing SOC1 transcription under drought conditions . This mechanism might contribute to adaptation by enabling plants to complete their life cycles under drought stress. | Keumbi Hwang Hendry Susila Zeeshan Nasim Ji-Yul Jung Ji Hoon Ahn | 2019 | Molecular Plant2019,12,4: | 12 |
| 2 | Biliary brush cytology:Factors associated with positive yields on biliary brush cytology显示文摘AIM: To evaluate the yield of brushing biliary strictures and the factors associated with a positive result in biliary strictures. METHODS: Data on all consecutive patients (01/02 -10/05) who were identified to have a biliary stricture and who underwent biliary brush cytology were collected. The yield of positive biliary brush cytology was evaluated and compared to results with the gold standard for diagnosis (defi ned as either defi nitive surgical histology or clinical course). Additionally,associated factors of positive results including stricture location,gender,age,mass size,length of stricture,and dilatation prior to brushing cytology were assessed. RESULTS: From 199 patients who had brushing cytology samples (10 patients were excluded due to lack of gold standard diagnosis),77 patients had positive brushing cytology (yield 41%). Variables associated with positive cytology brushing on initial endoscopic retrograde cholangiography were age 1.02 (1.00-1.05),mass size > 1 cm 2.22 (1.01-4.89) and length of stricture > 1 cm 3.49 (1.18-10.2). The sensitivity of biliary brushing was 61%,its specifi city 98%,the positive predictive value reached 99%,and the negative predictive value was 57%. CONCLUSION: Our results revealed a 41% positive yield from brushing cytology. The sensitivity of biliary brushing cytology in our center was 61% and the specif icity was 98%. Predictors of positive yield include older age,mass size > 1 cm,and stricture length of > 1 cm. | Nasim Mahmoudi Robert Enns Jack Amar Jaber AlAli Eric Lam Jennifer Telford | 2008 | World Journal of Gastroenterology2008,14,4: | 10 |
| 3 | Effects of dietary fiber and threonine on performance,intestinal morphology and immune responses in broiler chickens显示文摘The present experiment was conducted to investigate the effects of fiber and threonine(Thr)on growth performance,intestinal morphology and immune responses of broiler chickens.A total of 420 one-dayold mixed sex broiler chicks(Ross 308)were randomly divided into 6 experimental diets and 5 replicates of 14 chicks based on a factorial arrangement(2 × 3)from 1 to 42 d of age.Experimental factors included dietary supplemental fiber type(no supplemental fiber[NSF],30 g/kg sugar beet pulp[SBP]or 30 g/kg rice hull[RH])and Thr inclusion level(100% or 110% of Thr requirement recommended by breeder company[Ross 308]).Growth performance of broilers was assayed at different periods of the experiment.Intestinal morphometric features were measured at 21 d of age.Antibody titer against sheep red blood cells(SRBC),Newcastle and influenza disease viruses were measured on d 30 of trial.Dietary inclusion of SBP and RH significantly decreased feed intake and weight gain during the entire rearing period(P<0.05).Interaction of fiber and Thr had no beneficial effects on the performance of chickens across the entire rearing phase.Dietary supplementation of 110% Thr required level improved jejunal morphometric features(P<0.05),whereas its inclusion with fibrous materials failed to show the same effects.Dietary supplemental Thr together with SBP significantly increased antibody production against SRBC(P<0.05).In conclusion,although supplemental 30 g/kg fibrous materials impaired growth performance,inclusion of SBP along with 110% Thr level improved the humoral immunity in broiler chickens. | Nasim Saadatmand Majid Toghyani Abasali Gheisari | 2019 | Animal Nutrition2019,,3: | 7 |
| 4 | Prognostic value of cortisol and thyroid function tests in poisoned patients admitted to toxicology ICU显示文摘BACKGROUND: Prognostic value of cortisol and thyroid function tests(TFTs) has previously been evaluated in medical ICUs. We aimed to evaluate prognostic efficacy of cortisol and TFTs in critically ill poisoned patients admitted to toxicology intensive care unit(ICU).METHODS: In a prospective study of consecutively enrolled subjects admitted to the toxicology ICU, lab analyses included TFTs(total T3 and T4 as well as TSH) and cortisol levels drawn between 8 am–10 am during period of the first 24 hours post-ingestion/exposure. Simplified Acute Physiology Score Ⅱ(SAPS Ⅱ) and Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ) were recorded. All scores were compared to detect the best prognostic factor. Type of poisoning was also included.RESULTS: In 200 patients evaluated, 129 were male and mean age was 31 years. In general, SAPS Ⅱ, T4, and cortisol could prognosticate death. After regression analysis, only cortisol had such efficacy(P=0.04; OR=1.06; 95%CI=1.05–1.08; cut-off=42 μg/d L; sensitivity=70%; specificity=82%). Between aluminium phosphide(ALP)-and non ALP-poisoned patients, level of consciousness, mean arterial pressure, and cortisol level could prognosticate death in ALP poisoning(all Ps<0.001 in both uni and multivariate analyses). Median(interquartile range; IQR) GCS was 7(6, 10) and 15(8, 15) in non-ALP and ALP-poisoned patients(P<0.003). SAPS Ⅱ and APACHE Ⅱ could not prognosticate death at all.CONCLUSION: Cortisol best prognosticated outcomes for subjects admitted to the toxicology ICU. Its level is higher in ALP-poisoned patients probably due to the higher stress while they remain conscious till the final stages of toxicity and are aware of deterioration of their clinical condition or may be due to their significantly lower blood pressures. | Shahin Shadnia Nasim Zamani Hossein Hassanian-Moghaddam Hamed Shafaroodi Mina Padandar Mohammad Hasan Rezaeizadeh | 2018 | World Journal of Emergency Medicine2018,9,1: | 6 |
| 5 | A review of high-strength nanolaminates and evaluation of their properties显示文摘Nanolaminates are composed of nanoscale-thick alternating layers of different materials and their properties are dependent on the individual layers,the layer thickness and the interfaces between the layers.Nanolaminates composed of cubic crystal structured metals are usually ductile compared to nanolaminates containing hexagonal crystal structured metals.Mechanical properties such as strength and hardness of nanolaminates increase with a decrease in individual layer thickness down to a few nanometers and they become independent when the thickness of individual layers is less than a couple of nanometers.This review provides a detailed analysis of the effects of individual layer thickness and the interface structures on the strength and the strengthening mecha nisms of nanolaminates,their ductility and fracture behavior in terms of structural variations including grain morphologies,nanotwins,amorphous phases and crystal structures of the layers.The principles for designing nanolaminates with exceptionally high mechanical and physical properties and their fabrication are also highlighted.Some contradictory issues such as strengthening mechanisms,elastic modulus dependency on individual layer thickness and the effect of a thin amorphous layer on the strength are discussed.This review also provides future research directions in designing the high-strength nanolaminates that will facilitate practical engineering applications through analyzing up-to-date research efforts. | Mohammad Nasim Yuncang Li Ming Wen Cuie Wen | 2020 | Journal of Materials Science & Technology2020,47,15: | 6 |
| 6 | An attending physician float shift for the improvement of physician productivity in a crowded emergency department显示文摘BACKGROUND:Patients backlogged in the emergency department(ED) waiting for an inpatient bed(boarders) continue to require the attention of ED physicians,exacerbating crowding in the ED.To address this problem,we added a 'float shift' to our winter schedule solely to care for boarders.We sought to quantify the effect of this float shift,hypothesizing greater physician productivity.METHODS:We performed a retrospective observational study in our community hospital ED,measuring the number of new patients seen in each 10-hour shift in the presence or absence of a float shift physician.We calculated the number of new patients seen per shift for each of the 7 daily shifts,during February(float shift scheduled) and May(float shift unscheduled) of 2008.We then compared the mean number of patients seen per shift in February with May.RESULTS:Total monthly patient volume was 6 656 for February and 6 775 for May,with the mean daily census being 230 and 219 patients,respectively.The number of new patients seen during each shift was greater in February than in May,with a mean increase of 1.1 patients per shift(with the float shift).Surveying participants about intervention effectiveness showed 92%of residents,but only 65%of attending physicians,in favor of maintaining the float shift.CONCLUSION:The presence of a 'float shift' physician caring only for boarding patients allows other physicians to maintain and even increase their productivity in our ED,despite the presence of longer throughput times and increased time on diversion. | Muhammad Umer Nasim Chintan Mistry Robert Harwood Erik Kulstad Laura Tommaso | 2013 | World Journal of Emergency Medicine2013,4,1: | 6 |
| 7 | Seismic analysis of diagrid structural frames with shear-link fuse devices显示文摘This paper presents a new concept for enhancing the seismic ductility and damping capacity of diagrid structural frames by using shear-link fuse devices and its seismic performance is assessed through nonlinear static and dynamic analysis.The architectural elegancy of the diagrid structure attributed to its triangular leaning member configuration and high structural redundancy make this system a desirable choice for tall building design.However,forming a stable energy dissipation mechanism in diagrid framing remains to be investigated to expand its use in regions with high seismicity.To address this issue,a diagrid framing design is proposed here which provides a competitive design option in highly seismic regions through its increased ductility and improved energy dissipation capacity provided by replaceable shear links interconnecting the diagonal members at their ends.The structural characteristics and seismic behavior(capacity,stiffness,energy dissipation,ductility) of the diagrid structural frame are demonstrated with a 21-story building diagrid frame subjected to nonlinear static and dynamic analysis.The findings from the nonlinear time history analysis verify that satisfactory seismic performance can be achieved by the proposed diagrid frame subjected to design basis earthquakes in California.In particular,one appealing feature of the proposed diagrid building is its reduced residual displacement after strong earthquakes. | Nasim S. Moghaddasi B. Yunfeng Zhang | 2013 | Earthquake Engineering and Engineering Vibration2013,12,3: | 4 |
| 8 | Non-invasive diagnosis of H pylori infection: Evaluation of serological tests with and without current infection marker CIM显示文摘AIM:To evaluate the performance of commercially available immunochromatographic (ICT) and immunoblot tests covering the current infection marker CIM and conventional ELISA for the diagnosis of H pylori infection in adult dyspeptic patients. METHODS:Consecutive non-treated dyspeptic patients undergoing diagnostic endoscopy were tested for H pylori infection by culture, rapid urease test, and histology of gastric biopsy specimens. Serum from 61 H pylori infected and 21 non-infected patients were tested for anti-H pylori IgG antibodies by commercial ELISA (AccuBindTM ELISA, Monobind, USA), ICT (Assure H pylori Rapid Test, Genelabs Diagnostics, Singapore), and immunoblot (Helico Blot 2.1, Genelabs Diagnostics, Singapore) assays. ICT and immunoblot kits cover CIM among other parameters and their performance with and without CIM was evaluated separately. RESULTS:Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of ELISA were 96.7%, 42.8%, 83.1%, 81.8%, and 82.9%, of ICT were 90.1%, 80.9%, 93.2%, 73.9%, and 87.8%, of ICT with CIM were 88.5%, 90.4%, 96.4%, 73.0%, and 89.0%, of immunoblot were 98.3%, 80.9%, 93.7%, 94.4%, and 93.9%, and of immunoblot with CIM were 98.3%, 90.4%, 96.7%, 95.0%, and 96.3%, respectively. CONCLUSION:Immunoblot with CIM had the best performance. ICT with CIM was found to be more specific and accurate than the conventional ELISA and may be useful for non-invasive diagnosis of H pylori infection. | Sufi HZ Rahman M Golam Azam M Anisur Rahman MS Arfin M Mahbub Alam Tareq M Bhuiyan Nasim Ahmed Motiur Rahman Shamsun Nahar MS Hassan | 2008 | World Journal of Gastroenterology2008,14,8: | 4 |
| 9 | Effect of Stimulating the BL67 Point on Fetal Correction from Breech to Cephalic Presentation and Natural Delivery after the 36 Weeks of Pregnancy: A Randomized Clinical Trial显示文摘Objective:Various techniques are proposed for changing fetal presentation.We aimed to assess the effect of BL67 point stimulation on correcting breech presentation and natural delivery in women at 36-38 gestational weeks.Methods:A parallel single blinded randomized clinical trial was conducted on 72 eligible pregnant women with breech presentation at the 36 weeks of pregnancy.The subjects were divided into two groups-intervention(n=36)and control groups(n=36)by block randomization method.The intervention group stimulated the BL67 point by self-administration for 20 min once a day for 2 weeks.Finally,the appearance of cephalic presentation and rate of vaginal delivery was compared between the groups(n1=n2=32)using the Chi-square test and multivariate logistic regression.Results:The correction of breech to cephalic presentation occurred in 53.1% of patients in the intervention group.The adjusted relative risk(RR)for fetal correction from breech to cephalic was 1.80(RR=1.80,95%confidence interval[CI],1.13-5.17).It was shown that the stimulation of the BL67 point increased the correction of breech to cephalic presentation.In addition,the rate of vaginal delivery increased by>4-fold(RR=4.16,95%CI,2.54-6.82)by correction to cephalic presentation.Moreover,65.6%of mothers in intervention group and 90.6%in the control group underwent cesarean section.Conclusions:The stimulation of the BL67 point is a safe,inexpensive,and effective method that can be self-administered at home for fetal correction from breech to cephalic presentation in women with breech presentations during 36-38 gestational weeks.This promotes uncomplicated natural childbirth. | Khatereh Sourani Abolfazl Mohammadbeigi Nasim Khademi Azadeh Asgarian Imaneh Khaki Zohreh Ahmadi | 2020 | Reproductive and Developmental Medicine2020,4,2: | 3 |
| 10 | 极低频率电磁场对小鼠生育能力及着床前期子宫内膜和输卵管上皮细胞高度的影响(英文)显示文摘目的:探讨极低频率电磁场(extremely low-frequency electromagnetic field,ELF-EMF)对小鼠生育力和着床前期子宫与输卵管上皮细胞高度的影响。方法:80只雌性NMRI小鼠随机分为对照组和EMF组。对照组小鼠不接受EMF,EMF组小鼠接受50 Hz、0 .5 mT EMF,每次4 h,每周6次,连续2周。雌小鼠注射孕马血清促性腺激素和人绒毛膜促性腺激素促其排卵,与雄鼠交配。通过观察阴道栓形成确定小鼠妊娠后,冲洗子宫腔获得胚泡,取子宫角和输卵管组织用于光学显微镜检查。结果:EMF组小鼠平均胚泡数比对照组明显减少(P<0 .03)。光学显微镜下观察发现,EMF组小鼠输卵管上皮细胞高度较对照组明显增加,而子宫内膜上皮细胞高度与对照组比较差异无统计学意义。结论:ELF-EMF可能通过减少胚泡数目,增加输卵管上皮细胞高度而损伤雌性小鼠生育能力。 | Farzad RAJAEI Nasim BORHANI Fatemeh SABBAGH-ZIARANI Farhad MASHAYEKHI | 2010 | 中西医结合学报2010,8,1: | 3 |
| 11 | 工业用纯钛等径角挤压的显微组织控制方法综述(英文)显示文摘综述了工业用纯钛(CP-Ti)大塑性变形技术的等径角挤压工艺,主要集中在等径角挤压参数的影响,包括通道角和曲率角、挤压路径、挤压温度、挤压速度、内部产热、挤压道次和背压。为了获得CP-Ti的最大均匀性、晶粒细化和提高力学性能,对不同等径角挤压CP-Ti进行了表征,如显微组织、应力不均匀性和力学性能。研究表明,在挤压温度为450°C,挤压速度为1-3 mm/s,挤压路径为BC,加载背压,通道角和曲率角分别为90°和20°的条件下能获得最均匀的超细组织。 | Peiman Shahbeigi Roodposhti Nasim Farahbakhsh Apu Sarkar Korukonda Linga Murty | 2015 | Transactions of Nonferrous Metals Society of China2015,25,5: | 3 |
| 12 | Curcuma angustifolia ameliorates carbon tetrachloride-induced hepatotoxicity in HepG2 cells and Swiss albino rats显示文摘Objective:To determine the antioxidant and hepatoprotective potential of methanol extract of rhizome of Curcuma angustifolia(MECA)against carbon tetrachloride(CCl4)-induced hepatic damage in vitro and in vivo.Methods:DPPH,ABTS and reducing power assays were performed to estimate the antioxidant effect of MECA.In vitro cytotoxicity of MECA against HepG2 cells was evaluated,whereas serum biochemical parameters and levels of antioxidative enzymes were measured in vivo and in vitro.Additionally,histopathological studies were estimated in order to investigate the hepatoprotective efficacy of MECA.Furthermore,GC-MS analysis of the extract was performed to identify the chemical components.Results:MECA exhibited strong antioxidant activity and attenuated CCl4-induced decrease in the viability of HepG2 cells.Additionally,MECA significantly restored the ALT,AST,ALP,TP and albumin level in comparison with the CCl4 group.After pre-treatment with MECA,effects of SOD,CAT and GSH were increased as well as lipid peroxidation amount decreased on CCl4-induced hepatotoxicity in in vitro and in vivo model.Furthermore,histopathological observation confirmed that MECA reduced liver injury induced by CCl4 in rats.GC-MS analysis confirmed the presence of bioactive constituents such as α-tocopherol(12.27%),phytol(7.61%),squalene(3.71%),β-sitosterol(2.19%),eugenol(2.59%),curcumenol(1.20%),β-elemene(1.00%)and eucalyptol(0.89%).Conclusions:MECA contains antioxidant and hepatoprotective constituents such asα-tocopherol,phytol,squalene and eugenol and exerts hepatoprotective effect both in vitro and in vivo. | Sudipta Jena Asit Ray Diptirani Rath Ambika Sahoo Subhashree Singh Noohi Nasim Durga Madhab Kar Sanghamitra Nayak | 2019 | Asian Pacific Journal of Tropical Medicine2019,12,9: | 2 |
| 13 | A simple method for inducing nonalcoholic steatohepatitis with fibrosis显示文摘Background: Nonalcoholic fatty liver disease(NAFLD) is increasingly occurring in sedentary people, and may progress to NASH and hepatocellular carcinoma. It is essential to design affordable animal models for the study of various diseases, including fatty liver, which was the aim of the study. In this study, a high-fat diet was devised that triggers NASH’s animal model quickly and easily. High-fat diet(HFD) was used both with intra-mouth oral gavage and in combination with animal pellets.Methods: Twenty-four male C57 BL/6 J mice were divided into HFD and ND groups, which received a high-fat diet and a normal diet, respectively. At the end of the experiment(fourth week of treatment), body and liver weights, biochemical parameters, PPAR-α gene expression and histopathologic characteristics of the liver were evaluated.Results: During 4 weeks, body weight of mice did not show a significant increase in the HFD group compared to the ND group, while weight gain of the liver was significant. Histological assessment of the HFD group’s liver confirmed NASH symptoms. In the HFD group, HDL-c, SOD, catalase, FRAP, adiponectin, and PPAR-α decreased significantly, and lipid profiles, hepatic enzymes, MDA, leptin, and TNF-α showed a significant increase compared to the ND group.Conclusion: Our high-fat diet has successfully induced all aspects of NASH with fibrosis in 4 weeks, and with low cost. | Leyla Yahaghi Azadeh Ebrahim-Habibi Nasim Hayati-Roodbari Shiva Irani Parichehreh Yaghmaei | 2019 | Animal Models and Experimental Medicine2019,2,4: | 2 |
| 14 | Measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √sNN=200 GeV显示文摘High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion collisions.Redistribution of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic backgrounds.We report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR experiment.The correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5 | L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderón de la Barca Sánchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanád M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.JI J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana M.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan M.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev M.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga Mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli J.H.Kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Nasim Md K.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa S.Oh V.A.Okorokov B.S.Page R.Pak A.Pandav Y.Panebratsev B.Pawlik D.Pawlowska H.Pei C.Perkins L.Pinsky R.L.Pintér J.Pluta J.Porter M.Posik N.K.Pruthi M.Przybycien J.Putschke H.Qiu A.Quintero S.K.Radhakrishnan S.Ramachandran R.L.Ray R.Reed H.G.Ritter O.V.Rogachevskiy J.L.Romero L.Ruan J.Rusnak N.R.Sahoo H.Sako S.Salur J.Sandweiss S.Sato W.B.Schmidke N.Schmitz B.R.Schweid F.Seck J.Seger M.Sergeeva R.Seto P.Seyboth N.Shah E.Shahaliev P.V.Shanmuganathan M.Shao A.I.Sheikh F.Shen W.Q.Shen S.S.Shi Q.Y.Shou E.P.Sichtermann R.Sikora M.Simko J.Singh S.Singha N.Smirnov W.Solyst P.Sorensen H.M.Spinka B.Srivastava T.D.S.Stanislaus M.Stefaniak D.J.Stewart M.Strikhanov B.Stringfellow A.A.P.Suaide M.Sumbera B.Summa X.M.Sun X.Sun Y.Sun Y.Sun B.Surrow D.N.Svirida P.Szymanski A.H.Tang Z.Tang A.Taranenko T.Tarnowsky J.H.Thomas A.R.Timmins D.Tlusty M.Tokarev C.A.Tomkiel S.Trentalange R.E.Tribble P.Tribedy S.K.Tripathy O.D.Tsai Z.Tu T.Ullrich D.G.Underwood I.Upsal G.Van Buren J.Vanek A.N.Vasiliev I.Vassiliev F.Videbæk S.Vokal S.A.Voloshin F.Wang G.Wang J.S.Wang P.Wang Y.Wang Y.Wang Z.Wang J.C.Webb P.C.Weidenkaff L.Wen G.D.Westfall H.Wieman S.W.Wissink R.Witt Y.Wu Z.G.Xiao G.Xie W.Xie H.Xu N.Xu Q.H.Xu Y.F.Xu Y.Xu Z.Xu Z.Xu C.Yang Q.Yang S.Yang Y.Yang Z.Yang Z.Ye Z.Ye L.Yi K.Yip H.Zbroszczyk W.Zha C.Zhang D.Zhang S.Zhang S.Zhang X.P.Zhang Y.Zhang Y.Zhang Z.J.Zhang Z.Zhang Z.Zhang J.Zhao C.Zhong C.Zhou X.Zhu Z.Zhu M.Zurek M.Zyzak | 2020 | Chinese Physics C2020,44,10: | 2 |
| 15 | Trend of blood lactate level in acute aluminum phosphide poisoning显示文摘BACKGROUND: Aluminum phosphide(Al P) poisoning is common in the developing countries. There is no specifi c antidote for the treatment of acute Al P poisoning. Early diagnosis of poisoning and outcome predictors may facilitate treatment decisions. The objective of this study was to determine the trend of blood lactate level in acute Al P poisoning to evaluate its role as a prognostic factor.METHODS: This was a prospective study on acute Al P intoxicated patients during one year. Demographic data, clinical and laboratory data on admission, and outcome were recorded in a selfmade questionnaire. Blood lactate levels were analyzed every two hours for 24 hours.RESULTS: Thirty-nine(27 male, 12 female) patients were included in the study. The mortality rate was 38.5%. The mean blood pressure, pulse rate, blood p H and serum bicarbonate level were significantly different between the survivors and non-survivors groups. Blood lactate level was signifi cantly higher in the non-survivors group during 8 to 16 hours post ingestion.CONCLUSION: Blood lactate level could be used as an index of severity of acute Al P poisoning. | Peyman Erfantalab Kambiz Soltaninejad Shahin Shadnia Nasim Zamani Hossein Hassanian-Moghaddam Arezou Mahdavinejad Behrooz Hashemi Damaneh | 2017 | World Journal of Emergency Medicine2017,8,2: | 2 |
| 16 | Group psychological intervention for maternal depression: A nested qualitative study from Karachi, Pakistan显示文摘AIM To understand the experience of maternal depression, the factors implicated in accessing health, and the acceptability of the psychosocial intervention. METHODS The participants were recruited from the paediatrics outpatient department of Civil Hospital Karachi, Pakistan. The study started in December 2009 and completed in December 2010. Women with maternal depression, aged 18-44 years with children aged 0-30 mo who had received nutritional supplements, and participated in the intervention programme [called Learning through Play(LTP) plus] were included in the study. Qualitative interviews were conducted with 8 participants before the intervention and 7 participants after the intervention. A semi structured topic guide was used to conduct the interviews.RESULTS Framework analysis procedures were used to analyse the qualitative data. Four themes emerged:(1) the women's contextual environment: Interpersonal conflicts, lack of social support and financial issues being the major barriers in assessing healthcare;(2) women's isolation and powerlessness within the environment: Sense of loneliness was identified as a restricting factor to access healthcare;(3) the impact of the intervention(LTP-Plus): Women felt 'listened to' and seemed empowered; and(4) empowered transformed women within the same contextual environment: The facilitator provided a 'gardening role' in nurturing the women resulting in a positive transformation within the same environment. The women's homes seemed to be more happy homes and there was a positive change in their behaviour towards their children.CONCLUSION Findings informed the further development and testing of culturally-appropriate psychosocial intervention(LTP^+) for addressing maternal depression. | Nusrat Husain Nasim Chaudhry Christine Furber Hina Fayyaz Tayyeba Kiran Farah Lunat Raza Ur Rahman Saira Farhan Batool Fatima | 2017 | World Journal of Psychiatry2017,7,2: | 2 |
| 17 | Nanoengineered Shear-Thinning Hydrogel Barrier for Preventing Postoperative Abdominal Adhesions显示文摘More than 90%of surgical patients develop postoper-ative adhesions,and the incidence of hospital re-admissions can be as high as 20%.Current adhesion barriers present limited efficacy due to difficulties in application and incompatibility with minimally invasive interventions.To solve thisclinical limitation,we developed an injectable and sprayable shear-thinning hydrogel barrier(STHB)composed of silicate nanoplatelets and poly(ethylene oxide).We optimized this technology to recover mechanical integrity after stress,enabling its delivery though inject-able and sprayable methods.We also demonstrated limited cell adhesion and cytotoxicity to STHB compositions in vitro.The STHB was then tested in a rodent model of peritoneal injury to determine its e cacy preventing the formation of postoperative adhesions.After two weeks,the peritoneal adhesion index was used as a scoring method to determine the formation of postoperative adhesions,and STHB formulations presented superior e cacy compared to a commercially available adhesion barrier.Histological and immunohistochemical examination showed reduced adhesion formation and minimal immune infiltration in STHB formulations.Our technology demonstrated increased e cacy,ease of use in complex anatomies,and compatibility with di erent delivery methods,providing a robust universal platform to prevent postoperative adhesions in a wide range of surgical interventions. | Guillermo U.Ruiz-Esparza Xichi Wang Xingcai Zhang Sofia Jimenez-Vazquez Liliana Diaz-Gomez Anne-Marie Lavoie Samson Afewerki Andres AFuentes-Baldemar Roberto Parra-Saldivar Nan Jiang Nasim Annabi Bahram Saleh Ali K.Yetisen Amir Sheikhi Thomas H.Jozefiak Su Ryon Shin Nianguo Dong Ali Khademhosseini | 2021 | Nano-Micro Letters2021,13,12: | 2 |
| 18 | Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients显示文摘 | Tessa Gordon Nasim Amirjani David C. Edwards K. Ming Chan | 2009 | Experimental Neurology2009,,1: | 2 |
| 19 | Anti-inflammatory isoflavonoids from the rhizomes of Iris germanica显示文摘 | Atta-ur-Rahman Shama Nasim Irfan Baig | | 0,,: | 1 |
| 20 | Novel animal models of affective disorders显示文摘 | Eva E Redei Nasim Ahmadiyeh Amber E Baum | 2001 | Semin Clin Neuropsychiatry2001,6,1: | 1 |