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| 1 | Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers显示文摘AIM:To determine the expression of membrane-bound mucins and glycan side chain sialic acids in Helicobacter pylori(H.pylori)-associated,non-steroidal inflammatory drug(NSAID)-associated and idiopathic-gastric ulcers.METHODS:We studied a cohort of randomly selected patients with H.pylori(group 1,n=30),NSAID(group 2,n=18),combined H.pylori and NSAID associated gastric ulcers(group 3,n=24),and patients with idiopathic gastric ulcers(group 4,n=20).Immunohistochemistry for MUC1,MUC4,MUC17,and staining for Erythrina cristagalli agglutinin and Sambucus nigra agglutinin(SNA)lectins was performed on sections from the ulcer margins.RESULTS:Staining intensity of MUC17 was higher in H.pylori ulcers(group 1)than in idiopathic ulcers(group4),11.05±3.67 vs 6.93±4.00 for foveola cells,and10.29±4.67 vs 8.00±3.48 for gland cells,respectively(P<0.0001).In contrast,MUC1 expression was higher in group 4 compared group 1,9.89±4.17 vs 2.93±5.13 in foveola cells and 7.63±4.60 vs 2.57±4.50 for glands,respectively(P<0.0001).SNA lectin staining was increased in group 4,in parallel to elevated MUC1expression,indicating more abundantα2-6 sialylation in that group.CONCLUSION:Cytoplasmic MUC17 staining was sig-nificantly decreased in the cases with idiopathic ulcer.The opposite was observed for both MUC1 and SNA lectin.This observation may reflect important pathogenic mechanisms,since different mucins with altered sialylation patterns may differ in their protection efficiency against acid and pepsin. | Yaron Niv Doron Boltin Marisa Halpern Miriam Cohen Zohar Levi Alex Vilkin Sara Morgenstern Vahig Manugian Erica St Lawrence Pascal Gagneux Sukhwinder Kaur Poonam Sharma Surinder K Batra Samuel B Ho | 2014 | World Journal of Gastroenterology2014，20，40： | 5 |
| 2 | Influence of lead and zinc onratmal ereproductionat' biochemical and histopathological levels 显示文摘 | Batra N Nehru B Bansal M P | 2001 | J Appl Toxicol2001，21，6： | 1 |
| 3 | The effect of zinc supplementation on the effects of lead on the rat testis 显示文摘 | Batra N Nehru B Bansal M P | 1998 | Reproductive Toxicology1998，12，5： | 1 |
| 4 | The antimicrobial effi ciency of root oil against human pathogenic bacteria and phy topatbogenic fungi显示文摘 | Jaiswal K S Batra K A Mehta B K | 1984 | Phytopathol Z1984，109，1： | 1 |
| 5 | Consumer Responses to Advertising : the Effects of Ad Content, Emotions, and Attitude Toward the Ad on Viewing Time 显示文摘 | Thomas J Olney Morris B Holbrook Rajeev Batra | 1991 | Journal of Consumer Research1991，17，4： | 1 |
| 6 | Flux reactions in soldering显示文摘 | Batra N K See J B King T B | 1974 | Welding Journal1974，53，： | 1 |
| 7 | An envelope domain Ⅲ based chimeric antigen produced in Pichia pastoris elicits neutral- izing antibodies against all four dengue virus serotypes显示文摘 | Etemad B Batra G Raut R | 2008 | Am J Trop Med Hyg2008，79，3： | 1 |
| 8 | The Role of Managerial Learning and Interpretation in Strategic Persistence and Reorientation:an Empirical Exploration显示文摘 | Lant T.K Milliken F.J Batra B | | 0，，： | 1 |
| 9 | Amorphous enzyme aggregates; Stability toward heat and aqueous-organic co solvent mixtures 显示文摘 | TYAGI B BATRA R GUPTA M N | 1999 | Enzyme and Microbial Technology1999，24，： | 1 |
| 10 | The role of managerial learning and interpretation in strategic persistence and reorientation: An empirical exploration 显示文摘 | Lant T K Milliken F J Batra B | 1992 | Strategy Management Journal1992，13，8： | 1 |
| 11 | Technological capability and firm efficiency in Taiwan (China)显示文摘 | Aw B Y Batra G | 1998 | World Bank Economic Review1998，12，1： | 1 |
| 12 | En-doscopic septoplasty:revisitation of the technique,in-dications,and outcomes 显示文摘 | CHUNG B J BATRA P S CITARDI M J | 2007 | Am J Rhinol2007，21，： | 1 |
| 13 | Modified smoothed particle hydrodynamics method and its application to transient problems显示文摘 | Zhang G B Batra R C | 2004 | Computational Mechanics2004，34，： | 1 |
| 14 | Construction of an amperometric bilirubin biosensor based on covalent immobilization of bilirubin oxidase onto zirconia coated silica nanoparticles/chitosan hybrid film显示文摘 | Batra B Lata S Sunny | 2013 | Biosens Bioelectron2013，44，： | 1 |
| 15 | The effect of zinc supplementation on the effects of lead on the rat testis 显示文摘 | Batra N Nehru B Bansal M P | 1998 | Reprod Toxicol1998，12，5： | 1 |
| 16 | Efficacy and limitation of a chlorhexidinebased decolonization strategy in preventing transmission of methicillinresistant Staphylococcus aureus in an intensive care unit 显示文摘 | Batra R Cooper B S Whiteley C | 2010 | Clin Infect Dis2010，50，2： | 1 |
| 17 | Pitfalls in the diagnosis of thoracic aortic dissection at CT angiography显示文摘 | Batra P Bigoni B Manning J | 2000 | Radiographics2000，20，2： | 1 |
| 18 | Construction of an amperometric bilirubin biosensor based on covalent immobilization of bilirubin oxidase onto zirconia coated silica nanoparticles/chitosan hybrid film显示文摘 | Batra B Lata S Sunny | 2013 | Biosensors and Bioelectronics2013，44，： | 1 |
| 19 | Diffusion Bonding of a Cu-Cr-Zr Alloy to Stainless Steel and Tungsten Using Nickel as an Interlayer显示文摘 | Batra I S Kale G B Saha T K | 2004 | Materials Science and Engineering2004，329，： | 1 |
| 20 | The Effects of ad Content,Emotions,and Attitude Toward the ad on Viewing Time显示文摘 | OLNEY T J HOLBROOK M B BATRA R | | 0，，03： | 1 |
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