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| 1 | Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: Involvement of cyclooxygenases and heat shock protein 70显示文摘AIM: To determine whether ischemic preconditioning (IP)affects the development of edematous cerulein-induced pancreatitis and to assess the role of cyclooxygenase-1 (COX-1), COX-2, and heat shock protein 70 (HSP 70) in this process.METHODS: In male Wistar rats, IP was performed by damping of celiac artery (twice for 5 min at 5-min intervals).Thirty minutes after IP or sham operation, acute pancreatitis was induced by cerulein. Activity of COX-1 or COX-2 was inhibited by resveratrol or rofecoxib, respectively (10 mg/kg).RESULTS: IP significantly reduced pancreatic damage in cerulein-induced pancreatitis as demonstrated by the improvement of pancreas histology, reduction in serum lipase and poly-C ribonuclease activity, and serum concentration of pro-inflammatory interleukin (IL)-1β.Also, IP attenuated the pancreatitis-evoked fall in pancreatic blood flow and pancreatic DNA synthesis.Serum level of anti-inflammatory IL-10 was not affected by IP. Cerulein-induced pancreatitis and IP increased the content of HSP 70 in the pancreas. Maximal increase in HSP 70 was observed when IP was combined with cerulein-induced pancreatitis. Inhibition of COXs, especially COX-2, reduced the protective effect of IP in edematous pancreatitis.CONCLUSION: Our results indicate that IP reduces pancreatic damage in cerulein-induced pancreatitis and this effect, at least in part, depends on the activity of COXs and pancreatic production of HSP 70. | Zygmunt Warzecha Artur Dembinski Piotr Ceranowicz Stanislaw J Konturek Marcin Dembinski Wieslaw W Pawlik Romana Tomaszewska Jerzy Stachura Beata Kusnierz-Cabala Jerzy W Naskalski Peter C Konturek | 2005 | World Journal of Gastroenterology2005，11，38： | 2 |
| 2 | ProGRP and NSE in therapy monitoring显示文摘 | Ewa W Jan K Beata S | 2008 | Anticancer Res2008，28，9： | 1 |
| 3 | Effect of sinus rhythm restoration on plasma brain natriuretic peptide in patients with atrial fibriilation显示文摘 | Beata W K | 2004 | Am J Cardiol2004，93，： | 1 |
| 4 | The kinetics of phenol decomposition under UV irradiation with and without H2O2 on TiO2, Fe-TiO2 and Fe-C-TiO2 photocatalysts显示文摘 | Beata T Antoni W M Michio I | 2006 | Applied Catalysis B: Environmental2006，63，34： | 1 |
| 5 | Activation of circulating platelets and platelet response to activating agents in children with cyanotic congenital heart disease:their relevance to palliative systemic-pulmonary shunt显示文摘 | Jerzy S Bogusl C W | 2001 | Int J Cardiol2001，79，： | 1 |
| 6 | Application of gas chromatography-olfactometry (GC-O) in analysis and quality assessment of alcoholic beverages-a review 显示文摘 | Beata P Waldemar W | 2008 | Food Chemistry2008，107，1： | 1 |
| 7 | The preparation of TiO2 - nitrogen doped by calcinations of TiO2·xH2O under ammonia atmosphere for visible light photocatalysis 显示文摘 | Beata K Sylwia M Antoni W | 2005 | Solar Energy Materials and Solar Cells2005，88，： | 1 |
| 8 | Preparation of exfoliated graphite by microwave irradiation显示文摘 | Tryba Beata Morawski Antoni W Inagaki Michio | 2005 | Carbon2005，43，11： | 1 |
| 9 | Overweight and obesity at school entry among migrant and German children:A cross-sectional study显示文摘 | Beata W Hajo Z | 2005 | BMC Public Health2005，5，： | 1 |
| 10 | Detection and differentiation of virulent and avirulent strains of Newcastle disease virus by real-time PCR显示文摘 | Dawid N W Lukasz R Beata G | 2011 | J Virol Methods2011，173，1： | 1 |
| 11 | Effect of Resveratrol, A Natural Polyphenolic Compound, on Platelet Activation Induced by Endotoxin or Thrombin显示文摘 | Beata O Barbara W Joanna S | 2002 | Thrombosis Research2002，107，3： | 1 |
| 12 | ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Peptide Receptor Radionuclide Therapy with Radiolabeled Somatostatin Analogs显示文摘 | Kwekkeboom Dik J Krenning Eric P Lebtahi Rachida Komminoth Paul Kos-kudla Beata De Herder Wouter W Pl?ckinger Ursula | 2009 | Neuroendocrinology2009，，2： | 1 |
| 13 | Aromagrams-aromatic profiles in the appreciation of food quality 显示文摘 | Beata P Waldemar W | 2007 | Food Chemistry2007，101，2： | 1 |
| 14 | Relationship between aortic pulse wave velocity, selected proinflammatory cytokines, and vascular calcification parameters in peritoneal dialysis patients显示文摘 | Marcin Krzanowski Katarzyna Janda Paulina Dumnicka Marzena Dubiel Ma?gorzata Stompór Beata Ku?nierz-Cabala Tomasz Grodzicki W?adys?aw Su?owicz | 2014 | Journal of Hypertension2014，，1： | 1 |
| 15 | Resveratrol,a phenolic antioxidant with effects on blood platelet functions显示文摘 | BEATA O BARBARA W | | 0，，05： | 1 |
| 16 | Assessment of ion imprinted polymers based on Pd(II) chelate complexes for preeoneen- tration and FAAS determination of Palladium显示文摘 | BEATA G BARBARA L IRENA W | 2012 | Talanta2012，83，： | 1 |
| 17 | Exfoliated graphite as a new sorbent for removal of engine oils from waster 显示文摘 | Beata T Antoni W M Ryszard J K N | 2003 | Spill Science & Technology Bulletin2003，8，56： | 1 |
| 18 | Aldonamide - type gemini surfactants : Synthesis, structural analysis, and biological properties 显示文摘 | KAZIMIERA A WILK LUDWIK SYPER BEATA W DOMAGALS- KA | 2002 | Journal of Surfactants and Detergents2002，5，3： | 1 |
| 19 | Correlation between erxpression of metallothionein and expression of Ki-67 and MCM-2 proliferation markers in non-small cell lung cancer显示文摘 | Bozena W Bartosz P Beata M | | 0，，09： | 1 |
| 20 | Monoeyte adhesion and spreading on human endothelial cells is dependent on rho- regulated receptor clustering显示文摘 | Beata W S Lynn W Anne J | 1999 | J Cell Biology1999，，： | 1 |
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