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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-anal- ysis 显示文摘 | Chu S G Becker R C Berger P B | 2010 | J Thromb Haemost2010，8，1： | 1 |
| 3 | Solid-phase crystalli-zation of amorphous silicon on ZnO:Al for thin-film solar cells显示文摘 | Becker C Conrad E Dogan P | 2009 | Solar Energy Mater Solar Cells2009，93，： | 1 |
| 4 | Martensite DecayDuring Rolling Contact Fatigue in Ball Bearings 显示文摘 | SWAHN H BECKER P C VINGSB0 O | 1976 | Metallurgical and Materials Transactions A1976，7，8： | 1 |
| 5 | Progression from acute to chronic pancreatitis:prognostic factors,mortality,and natural course显示文摘 | Najgaard C Becker U Matzen P | | 0，，08： | 1 |
| 6 | Contrast-Induced Nephropathy (CIN) Consensus Working Panel : executive summary 显示文摘 | MCCULLOUGH P A STACUL F BECKER C R | 2006 | Rev Cardiovasc Med2006，7，4： | 1 |
| 7 | Burnout, depression, and career satisfaction: Cross--sectional study of obstetrics and gynecology residents显示文摘 | Becker J L Milad M P Ktock S C | 2006 | 195(5) :1444-14492006，195，5： | 1 |
| 8 | A Qualitative EmpiricalModel of Cylinder Bore Wear 显示文摘 | Becker E P Ludema K C | 1999 | Wear1999，，1： | 1 |
| 9 | Cold-induced putative DEAD box RNA helicases CshA and CshB are essential for cold adaptation and interact with Cold Shock Protein B in Bacillus subtilis显示文摘 | Hunger K Beckering C L Wiegeshoff F Graumann P L Marahiel M A | 2006 | Journal of Bacteriology2006，188，1： | 1 |
| 10 | Evaluation of candidate vaccine approaches for mers-cov显示文摘 | Wang L Shi W Joyce M G Modjarrad K Zhang Y Leung K Lees C R Zhou T Yassine H M KanekiyoM Yang Z Y Chen X Becker M M Freeman M Vogel L Johnson J C Olinger G Todd J P Bagci U Solomon J Mollura D J Hensley L Jahrling P Deni- son M R Rao S S Subbarao K Kwong P D Mascola J R Kong W P Graham B S | 2015 | Nat Commun2015，6，： | 1 |
| 11 | Femtosec- ond photon echoes from band to band transitions in GaAs 显示文摘 | Becker P C Fragnito H L Brito Cruz C H | 1988 | Physical Review Letters1988，61，14： | 1 |
| 12 | Employee commitment and motivation: a conceptual analysis and integrative model显示文摘 | MEYER J P BECKER T E VANDENBERGHE C | 2004 | Journal of Applied Psychology2004，89，6： | 1 |
| 13 | Cutting edge: TGF-beta induces a regulatory phenotype in CD4^+ CD25^- T cells through Foxp3 induction and down-regulation of Smad 7显示文摘 | Fantini M C Becker C Monteleone G Pallone F Galle P R Neuratb M F | 2004 | J Inmmnol2004，172，51： | 1 |
| 14 | Contrast-induced nephropathy(CIN)Conse-nsus Working Panel:executive summary显示文摘 | Mc Cullough P A Stacul F Becker C R | 2006 | Rev Cardiovasc MED2006，7，4： | 1 |
| 15 | Beyond thrombosis:the versatile platelet in critical illness显示文摘 | Katz J N Kolappa K P Becker R C | 2011 | Chest2011，139，3： | 1 |
| 16 | A unified parametric design approach to structural shape optimization显示文摘 | ZHANG W H BECKERS P FLEURY C | 1995 | Int J Num Methods Eng1995，38，： | 1 |
| 17 | An optimized electroporation protocol applicable to a wide range of cell lines显示文摘 | Baum C Forster p Hegewisch Beckers | 1994 | Biotechniques1994，17，6： | 1 |
| 18 | Study of the reaction dynamics of Li + HF, HCl by the crossed molecular beams method显示文摘 | BECKER C H CASAVECCHIA P TIEDEMANN P W | 1980 | J Chem Phys1980，73，6： | 1 |
| 19 | An optimized electro-poration protocol applicable to a wide range of cell lines显示文摘 | Baum C Forster P Hegewisch Beckers | 1994 | Biotech-niques1994，17，6： | 1 |
| 20 | Dopamine from the brain promotes spinal motor neuron generation during de-velopment and adult regeneration显示文摘 | Reimer MM Norris A Ohnmacht J Patani R Zhong Z Dias TB Kuscha V Scott AL Chen YC Rozov S Frazer SL Wyatt C Higashijima S Pat-ton EE Panula P Chandran S Becker T Becker CG | | 0，，： | 1 |
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