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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 2 | Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial显示文摘 | Ronald P DeMatteo Karla V Ballman Cristina R Antonescu Robert G Maki Peter WT Pisters George D Demetri Martin E Blackstein Charles D Blanke Margaret von Mehren Murray F Brennan Shreyaskumar Patel Martin D McCarter Jonathan A Polikoff Benjamin R Tan Kouros | 2009 | The Lancet2009,,9669: | 2 |
| 3 | Adriamycin cardiomyopathy: risk factors显示文摘 | MINOW R A BENJAMIN R S LEE E T | 1977 | Cancer1977,39,4: | 1 |
| 4 | Prevalence,Clinical features and Prognosis of Diastolic Heart Failure:an Epidemiologic Perspective显示文摘 | Vasan R S Benjamin E J Levy D | 1995 | J Am Coll Cardiol1995,26,7: | 1 |
| 5 | The bedside insertion of inferior vena cava filters using ultrasound guidance 显示文摘 | UPPAL B FLINN W R Benjamin M E | 2007 | Perspect Vasc Surg Endovasc Ther2007,19,1: | 1 |
| 6 | Impact of at- rial fibrillation on the risk of death: the Framingham Heart Study显示文摘 | Benjamin E J Wolf P A D' Agostino R B | 1998 | Circulation1998,98,10: | 1 |
| 7 | Association of nocturnal arrhythmias with sleep-disordered breathing:the Sleep Heart Health Study显示文摘 | Mehra R Benjamin E J Shahar E | 2006 | Am J Respir Crit Care Med2006,173,8: | 1 |
| 8 | Sterically engineered perylene dyes for high efficiency oriented fluorophore luminescent solar eoncentrators显示文摘 | Benjamin W E Veit D R Perkins M J | 2014 | Chemistry of Materials2014,26,3: | 1 |
| 9 | Association of nocturnal arrhythmias with sleep-disordered breathing:The Sleep Heart Health Study显示文摘 | Mehra R Benjamin EJ Shahar E | 2006 | Am J Respir Crit Care Med2006,173,: | 1 |
| 10 | Giant duodenal ulcers显示文摘Giant duodenal ulcers (GDUs) are a subset of duoden ulcers that have historically resulted in greate morbidity than usual duodenal ulcers. Until recentl few cases had been successfully treated with medic therapy. However, the widespread use of endoscop the introduction of H-2 receptor blockers and proto pump inhibitors, and the improvement in surgic techniques all have revolutionized the diagnosi treatment and outcome of this condition. Nevertheles GDUs are still associated with high rates of morbidit mortality and complications. Thus, surgical evaluatio of a patient with a GDU should remain an integral pa of patient care. These giant variants, while usual benign, can frequently harbor malignancy. A caref review of the literature highlights the importan differences when comparing GDUs to classical pept ulcers and why they must be thought of different than their more common counterpart. | Eric Benjamin Newton Mark R Versland Thomas E Sepe | 2008 | World Journal of Gastroenterology2008,14,32: | 1 |
| 11 | A simple model for complex dynamical transitions in epidemics显示文摘 | Pejman R Benjamin M B | 2000 | Science2000,287,: | 1 |
| 12 | Association ofnocturnal arrhythmias with sleep disordered breathing: The Sleep Heart health Study显示文摘 | Mehra R Benjamin EJ Shahar E | 2006 | Am J Respir Crit Care Med2006,173,8: | 1 |
| 13 | Macrokinetic analysis of blockade of NMDA-gated currents by substituted alcohols, alkanes and ethers显示文摘 | Hugh E Criswell Zhen Ming Nathanial Pleasant Benjamin L Griffith Robert A Mueller George R Breese | 2004 | Brain Research2004,,1: | 1 |
| 14 | Quantitative studies of inhibitors of ADP ribosylation in vitro and in vivo 显示文摘 | Rankin P W Jacobson E L Benjamin R C | 1989 | J Biol Chem1989,264,8: | 1 |
| 15 | Risk factors AHA Conference Proceedings 显示文摘 | SACCO R L BENJAMIN E J BRODERICK J P | 1997 | Stroke1997,28,8: | 1 |
| 16 | Biology and clinical effects of nstural killer ceils in albgeneic transplantation 显示文摘 | BENJAMIN J E GILL S NE GRIN R S | 2010 | C urr Opin Oncol2010,22,2: | 1 |
| 17 | The multi- functional NS1 protein of influenza A viruses显示文摘 | BENJAMIN G H RICHARD E R JUAN O | 2008 | The Journal of General Virology2008,89,10: | 1 |
| 18 | Impact of atrial fibrillarion on the risk of death: the Framingham Heart Study显示文摘 | BENJAMIN E J WOKF P A AGOSTIO R B | 1998 | Circulation1998,98,: | 1 |
| 19 | Association of nocturnal arrhythmias with Sleep-disordered breathing:The Sleep Heart Health Study显示文摘 | Mehra R Benjamin EJ Shahar E | 2006 | Am J Respir Crit Care Med2006,173,8: | 1 |
| 20 | Tyrosine cross-links : molecular basis of gluten structure and function 显示文摘 | Tilley K A Benjamin R E Bagorogoza K E | 2001 | Journal of Agricultural and Food Chemistry2001,,49: | 1 |