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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Melanosis coli a consequence of anthraquinone Induced apoptosis of colonic epithelial cells 显示文摘 | WALKER NI BENNETT RE AXELSEN RA | 1998 | Am J Pathot1998，131，3： | 1 |
| 3 | Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication显示文摘 | Shinmura K Bennett RA Tarapore P | 2007 | Oncngene2007，26，20： | 1 |
| 4 | High versus low do-sing of oral colchicine for early acute gout flare显示文摘 | Terkeltaub RA Furst DE Bennett K | 2010 | Arthritis Rhe-um2010，62，4： | 1 |
| 5 | High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multiceuter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study显示文摘 | Terkeltaub RA Furst DE Bennett K | 2010 | Arthritis Rheum2010，62，4： | 1 |
| 6 | Melanosis coli: A consequence of anthraquinone-induced apoPtosis of colonic epithelial cells显示文摘 | WALKER NI BENNETT RE AXELSEN RA | 1988 | Am J Pathol1988，131，3： | 1 |
| 7 | Molecular ceil biology of androgen receptor signalling显示文摘 | Bennett NC Gardiner RA Hooper JD | 2010 | Int J Biochem Cell Biol2010，42，6： | 1 |
| 8 | Progress in symmetric ICF capsule implosions and wire-array Z-pinch source physics for double-pinch-driven hohlraums显示文摘 | Cuneo M E Vesey RA Bennett G R | 2006 | Plasma Physics and Controlled Fusion2006，48，2： | 1 |
| 9 | TSG101expression in gynecological tumors:relationship to cydin D1,cydin E,p53 and p16 protein显示文摘 | Bennett NA Pattillo RA Lin RS | 2001 | Cell/Viol Biol(Noisy-le-grand)2001，47，7： | 1 |
| 10 | High versuslow dosing of oral colchicine for early acute gout flare:twenty-four-hour outcome of the first multicenter,ran-domized,double-blind,placebo-controlled,parallel-group,dose-comparison colchicine study显示文摘 | Terkeltaub RA Furst DE Bennett K | 2010 | Arthritis Rheum2010，62，4： | 1 |
| 11 | p53 mutation and protein accumulation during multistage human esophageal carcinogenesis显示文摘 | Bennett WP Hollstein MC Metcalf RA | 1992 | Cancer Res1992，52，21： | 1 |
| 12 | In vitro elution of gentamicin, amikacin, and ceftiofur from polymethylmethacrylate and hydroxyapatite cement 显示文摘 | Ethell MT Bennett RA Brown MP | 2000 | Vet Surg2000，29，5： | 1 |
| 13 | Anxiety,depression,andstress as risk factors for atrial fibrillation after cardiac surgery显示文摘 | Tully PJ Bennetts JS Baker RA | | 0，，： | 1 |
| 14 | High versus low dosing of oral eolchieine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, ran- domized, double-blind, placebo-controlled, parallel-group, dose-comparison colehicine study 显示文摘 | Terkeltaub RA Furst DE Bennett K et ai | 2010 | Arthritis Rheum2010，62，4： | 1 |
| 15 | Computed tomography of primary transitional cell carcinoma of upper urinary tracts 显示文摘 | Badalament RA Bennett WF Bova JG | 1992 | Urology1992，40，1： | 1 |
| 16 | Novel vitiligo susceptibility loci on chromosomes ( AIS2 ) and $ ( AIS3 ), confirmation of SLEV 1 on chromosome 17 and their roles in an autoimmune diathesis显示文摘 | Sprita RA Gowan K Bennett DC | 2004 | Am J Hum Genet2004，74，1： | 1 |
| 17 | Praziquantel: The enigmatic antiparasitic显示文摘 | Day TA Bennett JL Pax RA | 1992 | Parasitol Today1992，8，： | 1 |
| 18 | Extracorporeal shock wave lithotripsy(ESWL):patient education & nursing care显示文摘 | Bennett WG Watson RA Heard JK | 1987 | Am J Gastroenterol1987，82，10： | 1 |
| 19 | Praziquantel: physiological evidence for its site(s) of action in magnesium-paralyzed Schistosoma mansoni显示文摘 | Blair KL Bennett JL Pax RA | 1992 | Parasitology1992，104，： | 1 |
| 20 | Assessment of myocardial injury by Troponin T in off-pump coronary artery grafting and conventional coronary artery graft surgery显示文摘 | Bennetts JS Baker RA Ross IK | 2002 | Aust N Z J Surg2002，72，： | 1 |
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