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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study显示文摘 | Mark S Pearce Jane A Salotti Mark P Little Kieran McHugh Choonsik Lee Kwang Pyo Kim Nicola L Howe Cecile M Ronckers Preetha Rajaraman Alan W Craft Louise Parker Amy Berrington de González | 2012 | The Lancet . 2012 (9840)2012，，： | 3 |
| 3 | Comparison of pregnancy outcome of pronuclear-and muhicelllular-stage frozen-thawed embryo transfers显示文摘 | Kattrea S Shrivastav P Craft I | 1999 | Assist Reprod Genet1999，16，7： | 1 |
| 4 | Insulin and neurodegenerative disorders 显示文摘 | Craft S Watson GS | 2004 | Lancet Neurol2004，3，： | 1 |
| 5 | Cerebrospinal fluidand plasma insulin levels in Alzheimer's disease: relationshipto severity of dementia and apolipoprotein E genotype 显示文摘 | Craft S Peskind E Schwartz MW | 1998 | Neurology1998，50，1： | 1 |
| 6 | Role of IL-1 in poststroke depressive- like behavior in mice 显示文摘 | Craft T K S DeVries A C | 2006 | Biological psychiatry2006，60，8： | 1 |
| 7 | Insulin resistance, inflammation, and cognition in Alzheimer's Disease: lessons for multiple sclerosis显示文摘 | Watson GS Craft S | 2006 | J Neurol Sci2006，245，12： | 1 |
| 8 | Determination of the principal directions of azimuthal anisotropy from P-wave seismic data 显示文摘 | Mallick S Craft K L Meister L J | 1998 | Geophysics1998，63，2： | 1 |
| 9 | Toxicity of arsenic, borax, chlorate and their combinations in three California soils显示文摘 | Crafts A S Cleary C W | 1936 | Hilgardia1936，10，： | 1 |
| 10 | Active vibration control using optimized modified acceleration feedback with Adaptive Line Enhancer for frequency tracking显示文摘 | Mahmoodi N Craft S Southward M J | | 0，，： | 1 |
| 11 | Insulin and neurodegenerative disease: shared and specific mechanisms 显示文摘 | Craft S Watson GS | 2004 | Lancet Neurol2004，3，3： | 1 |
| 12 | Intracerebroventricular in-sulin enhances memory in a passive-avoidance task显示文摘 | Park CR Seeley RJ Craft S | 2000 | Physiol Behav2000，，68： | 1 |
| 13 | Glucocorticoid-induced impairment in declarative memory performance inadult humans 显示文摘 | Newcomer JW Craft S Hershey T | 1994 | J Neurosci1994，14，： | 1 |
| 14 | Y chromosome sequenceDNA ampi ifled from peripheral blood of women in early pregnancy显示文摘 | Thomas MR Williamson S Craft I | 1994 | Lancet1994，343，： | 1 |
| 15 | Insulin resistance and Alzheimer's disease pathogenesis:potential mechanisms and implications for treatment显示文摘 | Craft S | 2007 | Curr Alzheimer Res2007，4，2： | 1 |
| 16 | KNOX action in Arabidopsis is mediated by coordinate regulation of cytokinin and gibberellin ac- tivities 显示文摘 | Jasinski S Piazza P Craft J | 2005 | Current Biology2005，15，17： | 1 |
| 17 | Cognitive changes associated with supplementation of testosterone or dihydrotestosterone in mildly hypogonadal men:a preliminary report显示文摘 | Cherrier MM Craft S Matsumoto AH | 2003 | J Androl2003，24，： | 1 |
| 18 | Effects of sewage effluent and ethynyl oestradiol upon molecular markers of oestrogenic exposure, maturation and reproductive success in the sand goby (pomatoschistus minutus, pallas) 显示文摘 | Robinson C D Brown E Craft J A Davies I M Moffat C F Pirie D Robertson F Stagg R M Struthers S | 2003 | Aquatic Toxicology2003，62，2： | 1 |
| 19 | Determination of the principal directions of azimuthal anisotropy from P-wave seismicdata显示文摘 | Mallick S Craft K L Meister L J | 1998 | Geophysics1998，63，2： | 1 |
| 20 | The role of metabolic disorders in Alzheimer disease and vascular dementia:two roads converged显示文摘 | Craft S | | 0，，03： | 1 |
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