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1Statin use and risk of diabetes mellitus显示文摘The 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors, statins, are widely used in the primary and secondary prevention of cardiovascular diseases to lower serum cholesterol levels. As type 2 diabetes mellitus is accompanied by dyslipidemia, statins have a major role in preventing the long term complications in diabetes and are recommended for diabetics with normal low density lipoprotein levels as well. In 2012, United States Food and Drug Administration released changes to statin safety label to include that statins have been found to increase glycosylated haemoglobin and fasting serum glucose levels. Many studies done on patients with cardiovascular risk factors have shown that statins have diabetogenic potential and the effect varies as per the dosage and type used. The various mechanisms for this effect have been proposed and one of them is downregulation of glucose transporters by the statins. The recommendations by the investigators are that though statins can have diabetogenic risk, they have more long term benefits which can outweigh the risk. In elderly patients and those with metabolic syndrome, as the risk of diabetes increase, the statins should be used cautiously. Other than a subset of population with risk for diabetes; statins still have long term survival benefits in most of the patients.Bharti Chogtu Rahul Magazine KL Bairy 2015World Journal of Diabetes2015,6,2:8
2Sarcastic sentiment detection in tweets streamed in real time: a big data approach显示文摘S.K. Bharti B. Vachha R.K. Pradhan K.S. Babu S.K. Jena 2016Digital Communications and Networks2016,2,3:6
3Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may beArvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti 2014World Journal of Gastroenterology2014,20,22:4
4Correlations between ultrasonic pulse wave velocities and rock properties of quartz-mica schist显示文摘Physico-mechanical properties are critically important parameters for rocks. This study aims to examine some of the rock properties of quartz-mica schist(QMS) rocks in a cost-effective manner by establishing correlations between non-destructive and destructive tests. Using simple regression analysis, good correlations were obtained between the pulse wave velocities and the properties of QMS rocks. The results were further improved by using multiple regression analysis as compared to those obtained by the simple linear regression analysis. The results were also compared to the ones obtained by other empirical equations available. The general equations encompassing all types of rocks did not give reliable results of rock properties and showed large relative errors, ranging from 23% to 1146%. It is suggested that empirical correlations must be investigated separately for different types of rocks. The general empirical equations should not be used for the design and planning purposes before they are verified at least on one rock sample from the project site, as they may contain large unacceptable errors.Bharti Chawre 2018Journal of Rock Mechanics and Geotechnical Engineering2018,10,3:4
5Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil显示文摘Arvind Pandey Kanchan Vishnoi Sutapa Mahata Satyendra Chandra Tripathi Sri Prakash Misra Vatsala Misra Ravi Mehrotra Manisha Dwivedi Alok C. Bharti 2015Nutrition and Cancer2015,,8:2
6Nuclear factor-kappa B and cancer: its role in prevention and therapy 显示文摘Bharti AC Aggarwal BB 2002Biochem Pharmacol2002,64,56:2
7Leptospirosis: a zoonotic disease of global importance显示文摘Ajay R Bharti Jarlath E Nally Jessica N Ricaldi Michael A Matthias Monica M Diaz Michael A Lovett Paul N Levett Robert H Gilman Michael R Willig Eduardo Gotuzzo Joseph M Vinetz 2003The Lancet Infectious Diseases2003,,12:2
8Study of cyanide removal from contaminated water using zinc peroxide nanomaterial显示文摘The present study highlights the potential application of zinc peroxide(ZnO_2)nanomaterial as an efficient material for the decontamination of cyanide from contaminated water. A process patent for ZnO_2 synthesis has been granted in United States of America(US Patent number 8,715,612; May 2014),South Africa,Bangladesh,and India. The ZnO_2 nanomaterial was capped with polyvinylpyrrolidone(PVP)to control the particle size. The PVP capped ZnO_2nanomaterial(PVP-ZnO_2)before and after adsorption of cyanide was characterized by scanning electron microscope,transmission electron microscope,X-ray diffractometer,Fourier transform infrared spectroscopy and time of flight-secondary ion mass spectrometry. The remaining concentration of cyanide after adsorption by PVP-ZnO_2 was determined using ion chromatograph. The adsorption of cyanide over PVP-ZnO_2 was also studied as a function of p H,adsorbent dose,time and concentration of cyanide. The maximum removal of cyanide was observed in p H range 5.8–7.8 within 15 min. The adsorption data was fitted to Langmuir and Fruendlich isotherm and it has been observed that data follows both the isotherms and also follows second order kinetics.Himani Uppal S. Swarupa Tripathy Sneha Chawla Bharti Sharma M.K. Dalai S.P. Singh Sukhvir Singh Nahar Singh 2017Journal of Environmental Sciences2017,29,5:2
9Hearing Impairment in Children显示文摘Bharti Katbamna Teresa Crumpton Dilip R. Patel 2008The Pediatric Clinics of North America2008,,5:2
10Actinomycetes from solitary wasp mud nest and swallow bird mud nest: isolation and screening for their antibacterial activity显示文摘Vijay Kumar Alpana Bharti Vivek Kumar Gupta Omprakash Gusain Gajraj Singh Bisht 2012World Journal of Microbiology and Biotechnology2012,,3:2
11Anticancer potential of curcumincumin: preclinical and clinical stud- ies显示文摘Aggarwal BB Kumar A Bharti AC 2003Anticancer Res2003,23,1:1
12Synthesis, characterization and in vitro antiamoebic activity of 5-nitrothiophene-2-carboxaldehyde thiosemicarbazones and their palladium (Ⅱ) and ruthenium (Ⅱ) complexes 显示文摘Singh S Bharti N Naqvi F 2004Eur J Med Chem2004,39,:1
13Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization显示文摘Bharti AC Aggarwal BB 2002Ann NY Acad Sci2002,973,:1
14Curcumin (diferuloylmeth- ane ) down-regulates the constitutive activation of nuclear factor-kap- pa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis 显示文摘Bharti AC Donato N Singh S 2003Blood2003,101,3:1
15The analgesic effect of intrathecal dexmedetomidine or clonidine, with bupivacaine, in trauma patients undergoing lower limb surgery: a randomised, double-blind study 显示文摘Solanki S L Bharti N Batra Y K 2013Anaesth Intensive Care2013,41,1:1
16Nuclear factor-kappa B and cancer:its role in prevention and therapy显示文摘Bharti AC Aggarwal BB 0,,5:1
17Aplasia cutis congenita:clinical management of a rare congenital anomaly显示文摘Bharti G Groves L David LR 2011J Craniofac Surg2011,22,1:1
18AtROS1 overexpression provides evidence for epigenetic regu- lation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic to- bacco 显示文摘BHARTI P MAHAJAN M VIAHWAKARMA A K 2015Journal of Experirrntal Botany2015,6,19:1
19Curing and Thermal Behavior of Poly( allylazide) and Bismaleimides 显示文摘Varma I K Veena Choudhary Bharti Gaur Bimlesh Lochab Sonia Oberoi Rashmi Chanhan 2006Journal of Applied Polymer Science [J]2006,101,:1
20Biomarker discovery in lung cancer-promises and challenges of clinical proteomics 显示文摘BHARTI A MAP C SALGIA R 2007Mass Spectrom Rev2007,26,3:1
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