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| 1 | Comparison of one and three initial monthly intravitreal ranibizumab injection in patients with macular edema secondary to branch retinal vein occlusion显示文摘AIM: To compare three initial monthly intravitreal ranibizumab(IVR) injections followed by pro re nata(PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema(ME) secondary to branch retinal vein occlusion(BRVO).METHODS: Forty-two eyes of 42 patients who had IVR injections for BRVO were retrospectively studied. Eighteen eyes received 1 initial IVR injection(1+PRN group) and 24 eyes received 3 monthly IVR injections(3+PRN). At 1, 3, 6 and 12mo; spectral-domain optical coherence tomography(SD-OCT) was performed. Central macular thickness(CMT), the integrity of the external limiting membrane(ELM), the presence of subretinal fluid, cyst size, the presence of inner segment/outer segment(IS/OS) defect were determined.RESULTS: At baseline the mean CMT was 521.3±153.2 μm in the 3+PRN group while it was 438.1±162.4 μm in 1+PRN group. At the final visit, mean CMT was 278.3±87.8 μm in the 3+PRN group and 285.2±74.2 μm in the 1+PRN group(P=0.079). The changes in CMT over the entire study period were also comparable in both groups(243±160 μm in the 3+PRN group, and 152.9±175.3 μm in the 1+PRN group; P=0.090). At baseline, best-corrected visual acuity(BCVA) was 0.92±0.60 logarithm of the minimal angle of resolution(logMAR) in the 3+PRN group, while it was 0.72±0.46 logMAR in the 1+PRN group. Final BCVA was 0.42±0.55 logMAR in the 3+PRN group and 0.38±0.50 logMAR in the 1+PRN group(P=0.979). Additionally, the BCVA changes from baseline to final visit were not significantly different(-0.50±0.45 logMAR in the 3+PRN group, and-0.33±0.39 logMAR in the 1+PRN group; P=0.255).CONCLUSION: No significant differences in the anatomical or functional results are found between 3+PRN and 1+PRN regimens in the patients receiving ranibizumab for ME secondary to BRVO. Intact IS/OS and baseline BCVA are good predictor of the visual gain, while baseline CMT is a good predictor of the anatomical gain. | Alper Halil Bayat Akin Cakir Seyma Gülcenur Ozturan Selim Bolükbasi Burak Erden Mustafa Nuri Elcioglu | 2018 | International Journal of Ophthalmology(English edition)2018，11，9： | 6 |
| 2 | The relationship between mean platelet volume with microalbuminuria and glycemic control in patients with type II diabetes mellitus显示文摘 | ünübol M Ayhan M Güney E | 2012 | Platelets2012，23，6： | 1 |
| 3 | Enhanced sen- sitivity of dopaminergic neurons to rotenone-induced toxicity with aging 显示文摘 | Phinney AL Andringa G Bol JG | 2006 | Parkinsonism Relat Disorder2006，2，： | 1 |
| 4 | Can the quality of colonic surgery be improved by standardisation of surgical technique with complete mesocolic excision?显示文摘 | BERTELSEN G BOLS B INGEHOLM P | 2011 | Colorectal Dis2011，13，10： | 1 |
| 5 | Long-term follow-up and quality of life after closure of ventricular septal defect in adults显示文摘 | Bol Raap G Meijboom FJ Kappetein AP | | 0，，02： | 1 |
| 6 | Long-term follow-up and quality of life after closure of ventricular septal defect in adults显示文摘 | Bol Raap G Meijboom FJ Kappetein AP | 2007 | Eur J Cardiothorac Surg2007，32，2： | 1 |
| 7 | Carbon isotopic com- position of branched tetraether membrane lipids in soils suggest a rapid turnover and a heterotrophic life style of their source organism(s) 显示文摘 | Weijers J Wiesenberg G Bol R | 2010 | Biogeosci Disc2010，7，3： | 1 |
| 8 | Effect of mud composition on wear and friction of casing and tool joints显示文摘 | Bol G M | 1986 | SPE Drilling Engineering1986，，5： | 1 |
| 9 | Chemical doping of large-area stacked graphene films for use as transparent,conducting electrodes显示文摘 | KASRY A KURODA M A MARTYNA G J TULEVSKI G S BOL A A | 2010 | ACS Nano2010，4，7： | 1 |
| 10 | Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging 显示文摘 | Phinney AL Andringa G Bol JG | 2006 | Parkinsonism Relat Disord2006，12，4： | 1 |
| 11 | Effect of mud composition on wear and friction of casing and tool joints 显示文摘 | BOL G M | 1986 | SPE Drilling Engineering1986，1，5： | 1 |
| 12 | Folow-up after surgerical closure of congenital ventricular septal defect显示文摘 | Bol Raap G Weerheim J Kappetein Ap | 2003 | Eur J Cardiothorac Surg2003，24，： | 1 |
| 13 | Perception of facial expres- sions and voices and of their combination in the human brain显示文摘 | Pourtois G de Gelder B Bol A | 2005 | Cortex2005，41，1： | 1 |
| 14 | Investigation of the fine structure of acicular ferrite part 2显示文摘 | Bol'shakov V I Sukhomlin G D Kuksenko V I | | 0，，9： | 1 |
| 15 | Thermal decomposition of ammonium dinitramide vapor in a two-temperature flow reactor显示文摘 | Shmakov A G Korobeinichev O P Bol' shova T A | 2002 | Combustion Explosion and Shock Waves2002，38，3： | 1 |
| 16 | Physicochemical characterization of raw materials and co-products from the titanium dioxide industry显示文摘 | M.J. Gázquez J.P. Bolívar R. García-Tenorio F. Vaca | 2009 | Journal of Hazardous Materials2009，，2： | 1 |
| 17 | Acute aortic dissection:An update显示文摘 | Bekkers JA Bol Raap G Takkenberg JJ | 2012 | Eur J Cardiothorac Surg2012，7，： | 1 |
| 18 | Temporary tricuspid valve detachment in closure of congenital ventricular septal defect显示文摘 | Bol Raap G Boge RS AJ De jong PL | 1994 | Eur J Cardiothorac Surg1994，8，6： | 1 |
| 19 | Cyclodextrin Ketones with the Catalytic Group at the Secondary Rim and Their Effectiveness in Enzyme-Like Epoxidation ofStilbenesEur显示文摘 | Fenger T H Marinescu L G Bols M | 2011 | J Org Chem2011，，： | 1 |
| 20 | Physicochemical characterization of raw materials and co-products from the titanium dioxide industry显示文摘 | G ázquez M J Bolívar J P García-Tenorio R | 2009 | Hazardous Materials2009，166，23： | 1 |
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