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| 1 | Carcinoma in situ in a 7 mm gallbladder polyp: Time to change current practice?显示文摘Detection of polypoid lesions of the gallbladder is increasing in conjunction with better imaging modalities. Accepted management of these lesions depends on their size and symptomatology. Polyps that are symptomatic and/or greater than 10 mm are generally removed, while smaller, asymptomatic polyps simply monitored. Here, a case of carcinoma-in-situ is presented in a 7 mm gallbladder polyp. A 25-year-old woman, who had undergone a routine cholecystectomy, was found to have an incidental 7 mm polyp containing carcinoma in situ. She had few to no risk factors to alert to her condition. There are few reported cases of cancer transformation in gallbladder polyps smaller than 10 mm reported in the literature. The overwhelming consensus, barring significant risk factors for cancer being present, is that such lesions should be monitored until they become symptomatic or develop signs suspicious for malignancy. In our patient's case this could have led to the possibility of missing a neoplastic lesion, which could then have gone on to develop invasive cancer. As gallbladder carcinoma is an aggressive cancer, this may have led to a tragic outcome. | David Kasle Amir A Rahnemai-Azar Shahida Bibi Vinaya Gaduputi Brian F Gilchrist Daniel T Farkas | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，9： | 8 |
| 2 | Laparoscopic vs open partial colectomy in elderly patients:Insights from the American College of Surgeons- National Surgical Quality Improvement Program database显示文摘AIM: To compare the outcomes between the laparoscopic and open approaches for partial colectomy in elderly patients aged 65 years and over using the American College of Surgeons- National Surgical Quality Improvement Program(ACS NSQIP) database. METHODS: The ACS NSQIP database for the years 2005-2011 was queried for all patients 65 years and above who underwent partial colectomy. 1:1 propensity score matching using the nearest- neighbor method was performed to ensure both groups had similar preoperative comorbidities. Outcomes including postoperative complications, length of stay and mortality were compared between the laparoscopic and open groups. χ2 and Fisher's exact test were used for discrete variables and Student's t-test for continuous variables. P < 0.05 was considered significant and odds ratios with 95%CI were reported when applicable. RESULTS: The total number of patients in the ACS NSQIP database of the years 2005-2011 was 1777035. We identified 27604 elderly patients who underwent partial colectomy with complete data sets. 12009(43%) of the cases were done laparoscopically and15595(57%) were done with open. After propensity score matching, there were 11008 patients each in the laparoscopic(LC) and open colectomy(OC) cohorts. The laparoscopic approach had lower post-operative complications(LC 15.2%, OC 23.8%, P < 0.001), shorter length of stay(LC 6.61 d, OC 9.62 d, P < 0.001) and lower mortality(LC 1.6%, OC 2.9%, P < 0.001). CONCLUSION: Even after propensity score matching, elderly patients in the ACS NSQIP database having a laparoscopic partial colectomy had better outcomes than those having open colectomies. In the absence of specific contraindications, elderly patients requiring a partial colectomy should be offered the laparoscopic approach. | Umashankkar Kannan Vemuru Sunil K Reddy Amar N Mukerji Vellore S Parithivel Ajay K Shah Brian F Gilchrist Daniel T Farkas | 2015 | World Journal of Gastroenterology2015，21，45： | 3 |
| 3 | Analysis of marine DOC using a dry combustion method显示文摘 | BRIAN F PELTZER E T HOPKINSON C S | 1996 | Marine Chemistry Volume 541996，34，： | 1 |
| 4 | Analysis of marine DOC using a dry combustion method显示文摘 | BRIAN F PELTZER E T HOPKINSON C S | 1996 | Marine Chemistry1996，54，34： | 1 |
| 5 | Synthesis of Highly Ordered,Three-Dimensional,Macroporous Structures of Amorphous or Crystalline Inorganic Oxides,Phosphates,and Hybrid Composites显示文摘 | Brian T H Christopher F B Thang D | 2004 | Chem Mater2004，16，11： | 1 |
| 6 | Resourcereonstrained project scheduling with time- resource tradeoffs: The nonpreemptive case显示文摘 | Brian T F | 1982 | Management Science 19821982，，10： | 1 |
| 7 | Loss of kernel set due to water and shade in maize:Carbohydrate supplies,Abscisic acid,and Cytokinins显示文摘 | Setter T L Brian A F Melkonian J | 2001 | Crop Science2001，41，： | 1 |
| 8 | Resource-constrained project scheduling with time-resource tradeoffs:The nonpreemptive case显示文摘 | Brian T F | 1982 | Management Science1982，28，10： | 1 |
| 9 | General synthesis of periodic macroporous solids by templated salt precipitation and chemical conversion显示文摘 | HONGWEI Y CHRISTOPHER F B BRIAN T H | 2000 | Chem Mater2000，12，： | 1 |
| 10 | A chemical synthesis of periodic macroporous NiO and metallic Ni 显示文摘 | Yan Hongwei Blanford Christopher F Holland Brian T | 1999 | Adv Mater1999，11，12： | 1 |
| 11 | General synthesis of periodic macroporous solids by templated salt precipitation and chemical conversion显示文摘 | Yah Hongwei Blanford Christopher F Holland Brian T | 2000 | Chem Mater2000，12，4： | 1 |
| 12 | Formation of an N- formylkynurenine-derived fluorophore and its use for measuring indoleamine 2,3-dioxygenase 1 activity 显示文摘 | Petr T Brian D P Jack U F | 2013 | Anal Bioanal Chem2013，405，8： | 1 |
| 13 | The eIF2 ki- nase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress 显示文摘 | BRIAN F T SHEREE A W PIYAWAN B | 2011 | Molecular Bi- ology of the Cell2011，22，15： | 1 |
| 14 | Analysis of marine DOC using a dry combustion method 显示文摘 | Brian F Peltzer E T Hopkinson C S | 1996 | Marine Chemistry1996，54，34： | 1 |
| 15 | Evaluation of the Cd/hemoglobin affinity assays for the rapid determination of metallothionein in biological tissues 显示文摘 | David L E Brian F T | 1982 | Toxical Appl Pharmacol1982，66，： | 1 |
| 16 | Utilizing the USDA PLANT database to predict exotic woody plant invasiveness in New Hampshire显示文摘 | Brian F Robert T | 2003 | For Ecol Mange2003，185，： | 1 |
| 17 | Analysis of marine DOC using a dry combustion method显示文摘 | Brian F Peltzer E T Hopkinson C S | 1996 | Marine Chemistry1996，54，34： | 1 |
| 18 | Combined Oral Positive Inotropic and Beta-Blocker Therapy for Treatment of Refractory Class IV Heart Failure显示文摘 | Simon F Shakar William T Abraham Edward M Gilbert Alastair D Robertson Brian D Lowes Lawrence S Zisman Debra A Ferguson Michael R Bristow | 1998 | Journal of the American College of Cardiology1998，，： | 1 |
| 19 | Matrix and fiber influences on the cryogenic micro cracking of carbon fiber/epoxy composites显示文摘 | John F T Matthew S T Brian S H | 2003 | Composites Part A2003，41，： | 1 |
| 20 | Speed reduction mechanisms of transverse lines显示文摘 | STUART T G THOMAS T T BRIAN N F | | 0，，04： | 1 |
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