|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 2 | A striking local esophageal cytokine expression profile in eosinophilic esophagitis显示文摘 | Carine Blanchard Emily M. Stucke Beatriz Rodriguez-Jimenez Karen Burwinkel Margaret H. Collins Annette Ahrens Eileen S. Alexander Bridget K. Buckmeier Butz Sean C. Jameson Ajay Kaul James P. Franciosi Jonathan P. Kushner Philip E. Putnam J. Pablo Abonia M | 2010 | The Journal of Allergy and Clinical Immunology2010，，1： | 3 |
| 3 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 4 | The effect of noiseon children at school: a review显示文摘 | Bridget M Shield Julie E Dockrell | 2003 | Building Acoustics2003，10，2： | 1 |
| 5 | Cadmium,Lead,and Other Metals in Relation to Semen Quality:Human Evidence forMolybdenum as a Male Reproductive Toxicant显示文摘 | John D M Mary G R Bridget P | 2008 | Environ Health Perspect2008，116，11： | 1 |
| 6 | Predictors of postoperative movement and resting pain following total knee replace- ment显示文摘 | Rakel BA Blodgett NP Bridget Zimmerman M | 2012 | Pain2012，153，11： | 1 |
| 7 | Postoperative Complications After Primary Adult Optical Penetrating Keratoplasty: Prevalence and Impact on Graft Survival显示文摘 | Michael D Wagoner Rola Ba-Abbad Mansour Al-Mohaimeed Samar Al-Swailem M Bridget Zimmerman | 2009 | Cornea2009，，4： | 1 |
| 8 | Association between valsalva and cough leak point pressures and pelvic organ prolapsed quantification in women with stress ineontinence显示文摘 | Jerilyn ML Bridget M Karl JK | 2005 | J Urol2005，173，： | 1 |
| 9 | Approaches to pharmacy benefit management and the impact of consumer cost sharing显示文摘 | Bridget M Olson | 2003 | Clinical Therapeutics2003，，： | 1 |
| 10 | Effects of participation in a martial arts-based antibullying program in elementary schools 显示文摘 | Stuart W T Bridget K B Timothy D N Eric M V Peter F Stephen W T | 2008 | Psychology in the School2008，45，10： | 1 |
| 11 | Compliance: Regulation and Environment 显示文摘 | Bridget M Hutter | 1997 | Economic Globalization1997，，20： | 1 |
| 12 | Association between valsalva and cough leak point pressures and pelvic organ prolapsed quantification in women with stress incontinence 显示文摘 | Jerilyn ML Bridget M Karl JK | 2005 | J Urol2005，173，： | 1 |
| 13 | Bouchier-Hayes,Taurine attenuates LPS-induced and rolling and adhesion in rat microcirculation显示文摘 | Bridget M Egan Gang Chen Cathal J | 2001 | Journal of Surgical Research2001，95，： | 1 |
| 14 | Manchester Asthma and Allergy Study: Low - allergen environment can be achieved and maintained during pregnancy and in early life 显示文摘 | Adnan Custovic Bridget M Simpson | 2000 | J Allergy Clin Immunol2000，105，： | 1 |
| 15 | Predictors of postoperative movement and resting pain fol- lowing total knee replacement显示文摘 | RAKEL BA BLODGETT NP BRIDGET ZIMMERMAN M | 2012 | Pain2012，153，11： | 1 |
| 16 | Hypothermia Improves Defibrillation Success and Resuscitation Outcomes From Ventricular Fibrillation显示文摘 | Kimberly A. Boddicker Yi Zhang M Bridget Zimmerman Loyd R. Davies Richard E. Kerber | 2005 | Circulation2005，，24： | 1 |
| 17 | Inpalred FGF signaling contributes to cleft lip and palate显示文摘 | Bridget M Riley M Mansilla A | 2007 | Proc Natl Acad Sci U S A2007，104，11： | 1 |
| 18 | Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis 显示文摘 | Francois H Tianju Liu Bridget M | 2003 | Immunology2003，171，12： | 1 |
| 19 | Targeting the pancreatic β-cell to treat diabetes显示文摘 | Amedeo Vetere Amit Choudhary Scan M Burns Bridget K Wagner | 2014 | Nature Reviews Drug Discovery2014，13，： | 1 |
| 20 | Predictors ofpostoperative movement and resting pain following total knee re-placement 显示文摘 | Rakel BA Blodgett NP Bridget Zimmerman M | 2012 | Pain2012，153，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员