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| 1 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999，，9： | 3 |
| 2 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 3 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999，，9： | 2 |
| 4 | The effects of Spirulina on anemia and immune function in senior citizens显示文摘Anemia and immunological dysfunction(i.e.immunosenescence)are commonly found in older subjects and nutritional approaches are sought to counteract these phenomena.Spirulina is a filamentous and multicellular bule-green alga capable of reducing inflammation and also manifesting antioxidant effects.We hypothesized that Spirulina may ameliorate anemia and immunosenescence in senior citizens with a history of anemia.We enrolled 40 volunteers of both sexes with an age of 50 years or older who had no history of major chronic diseases.Participants took a Spirulina supplementation for 12 weeks and were administered comprehensive dietary questionnaires to determine their nutritional regimen during the study.Complete cell count(CCC)and indoleamine 2,3-dioxygenase(IDO)enzyme activity,as a sign of immune function,were determined at baseline and weeks 6 and 12 of supplementation.Thirty study participants completed the entire study and the data obtained were analyzed.Over the 12-week study period,there was a steady increase in average values of mean corpuscular hemoglobin in subjects of both sexes.In addition,mean corpuscular volume and mean corpuscular hemoglobin concentration also increased in male participants.Older women appeared to benefit more rapidly from Spirulina supplements.Similarly,the majority of subjects manifested increased IDO activity and white blood cell count at 6 and 12 weeks of Spirulina supplementation.Spirulina may ameliorate anemia and immunosenescence in older subjects.We encourage large human studies to determine whether this safe supplement could prove beneficial in randomized clinical trials. | Carlo Selmi Patrick SC Leung Laura Fischer Bruce German Chen-Yen Yang Thomas P Kenny Gerry R Cysewski M Eric Gershwin | 2011 | Cellular & Molecular Immunology2011，8，3： | 2 |
| 5 | Tooth loss and alveolar remodeling in Sinosaurus triassicus (Dinosauria: Theropoda) from the Lower Jurassic strata of the Lufeng Basin, China显示文摘Pathological or traumatic loss of teeth often results in the resorption and remodeling of the affected alveoli in mammals. However, instances of alveolar remodeling in reptiles are rare. A remodeled alveolus in the maxilla of the Chinese theropod Sinosaurus (Lower Jurassic Lower Lufeng Formation) is the first confirmed example of such dental pathology in a dinosaur. Given the known relationship between feeding behavior and tooth damage in theropods (teeth with spalled enamel, tooth crowns embedded in bone) and the absence of dentary, maxillary, and premaxillary osteomyelitis, traumatic loss of a tooth is most likely the cause of alveolar remodeling. Based on the extent of remodeling, the injury and subsequent tooth loss were non-fatal in this individual. | XING LiDa BELL Phil R ROTHSCHILD Bruce M RAN Hao ZHANG JianPing DONG ZhiMing ZHANG Wei CURRIE Philip J | 2013 | Chinese Science Bulletin2013，58，16： | 2 |
| 6 | Analysis of feline calicivirus capsid protein genes:identification of varia ble antigenic determinant regions of the protein显示文摘 | Bruce S S Julia F R William L M | 1993 | J Gen Virol1993，74，： | 1 |
| 7 | Economic incentives for agricultural nonpoint source pollution control显示文摘 | Bruce A L Marc R | 1994 | Water Resources Bulletin1994，30，3： | 1 |
| 8 | Adsorption of alkylthiol-capped gold nanoparticles onto alkylthiol self-assembled monolayers: An SPR study显示文摘 | Goren M Galley N Bruce Lennox R | 2006 | Langmuir2006，22，3： | 1 |
| 9 | Twenty years of inten- sive fertilization and competing vegetation suppression in loblolly pine plantations: Impacts on soil C,N, and microbial biomass显示文摘 | Sami W R Daniel M Bruce B | 2010 | Soil Biology & Biochemistry2010，42，5： | 1 |
| 10 | Power and machinery: seed loss when cutting a standing crop of oilseed rape with two types of combine harvester header 显示文摘 | Hobson R N Bruce D M | 2002 | Biosystems Engineering2002，81，3： | 1 |
| 11 | A comparison of methods for measuring water stable aggregates Implications for determining environmental effects on soil structure显示文摘 | Beare M H Bruce R R | 1993 | Geoderma1993，56，14： | 1 |
| 12 | Learning subjective language 显示文摘 | Wiebe J Wilson T Bruce R Bell M Martin M | 2004 | Computational linguistics2004，30，3： | 1 |
| 13 | Financing Constraints and Corporate Investment 显示文摘 | Fazzari Steven M R Glenn Hubbard Bruce C Petersen | 1988 | Brookings Paper on Economic Activity1988，19，1： | 1 |
| 14 | Sets of EcoRI fragments containing ribosomal RNA sequences are conserved among different strains of Listeria monocytogenes 显示文摘 | Bruce J L R J Hubner E M Cole | 1995 | Proc Natl Acad Sci1995，92，： | 1 |
| 15 | Effect of textile properties in evalu- ating a directional shading fabric 显示文摘 | MAUREEN M G BRUCE D H ARDIS M R | 1997 | Textile Research Journal1997，67，4： | 1 |
| 16 | Purification and primary structural charaeterization of prophenoloxidases from Aedes aegypti larvae显示文摘 | Junsuo S L Seong R K Bruce M C | 2005 | Insect Biochem Mol Biol2005，35，： | 1 |
| 17 | PPARγ: A nuclear regulator of metabolism, differentiation, and cell growth显示文摘 | Evan D R Bruce M S | 2001 | J Biol Chem2001，276，37： | 1 |
| 18 | Responses of three grass species to creosote during phytoremediation显示文摘 | Xiao-Dong Huang Yousef El-Alawi Donna M Penrose Bernard R Glick Bruce M Greenberg | 2004 | Environmental Pollution2004，，3： | 1 |
| 19 | Surgical management of craniopharyngiomas显示文摘 | KOMOTAR R J ROGUSKI M BRUCE J N | 2009 | J Neurooncol2009，92，3： | 1 |
| 20 | A comparison of the col- laborative information retrieval behavior of two design teams 显示文摘 | Bruce H Fidel R Pejtersen A M | 2003 | The New Review of Information Behavior Research2003，4，1： | 1 |
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