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10篇 您的检索式:作者名="Bu Dingfang"
    题名 作者 年代 出处 被引量
1Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice显示文摘Yanfei Wang Xia Zhao Hongfang Jin Hongling Wei Wei Li Dingfang Bu Xiuying Tang Yali Ren Chaoshu Tang Junbao Du 2009Arteriosclerosis Thrombosis and Vascular Biology2009,,2:2
2Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice显示文摘Yanfei Wang Xia Zhao Hongfang Jin Hongling Wei Wei Li Dingfang Bu Xiuying Tang Yali Ren Chaoshu Tang Junbao Du 2009Arteriosclerosis, Thrombosis, and Vascular Biology2009,,2:1
3The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats 显示文摘Zhang Chunyu Du Junbao Bu Dingfang 2003Biochem Biophys Res Commun2003,302,:1
4Changes of adrenomedullin and receptor activity modifying protein2(RAMP2)in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia显示文摘Qi Yongfen Shi Yanrong Bu Dingfang 2003Peptides2003,24,3:1
5The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats显示文摘Zhang Chunyu Du Junbao Bu Dingfang Yan Hui Tang Xiuying Tang Chaoshu 2003Biochemical and Biophysical Research Communications2003,,4:1
6The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats显示文摘Zhang Chunyu Du Junbao Bu Dingfang 2003Biochem Biophys Res Commun2003,302,4:1
7The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats 显示文摘Zhang Chunyu Du Junbao Bu Dingfang 2003Biochem Biophys Res Commun2003,302,:1
8Castleman's tumours and production of autoantibody in paraneoplastic pemphigus显示文摘Liangchun Wang Dingfang Bu Yong Yang 2004Lancet2004,363,:1
9Urotensin Ⅱ increases endothelin production by vascular smooth muscle cells in rats显示文摘The aim of this study was to observe the effects of urotensin Ⅱ (UII) on production of endothelin (ET) in rat aortic vascular smooth muscle cells (VSMC). Cultured VSMCs incubated with various concentrations of UII were used to measure the YSMC 3H-TdR incorporation, the amount of ET mRNA and ET production in VSMCs. In this work we found that UII (10-10-10-8 mol/L) promoted VSMC 3H-TdR incorporation (47%-83%, P<0.01) and increased the amount of ET mRNA by 17.1% (P < 0.05) to 112.8% (P < 0.01), respectively, in a concentration dependent manner compared with control. After 4 and 8 h incubation, 10-10-10-8 mol/L of UII elevated the ET synthesis and release in a concentration dependent manner. After 4 h incubation, the content of ET in medium was 4.9, 5.36 and 7.12 pg/mL (P < 0.01). After 8 h incubation, the ET content released from VSMCs was 12.6, 12.07 and 17.17 pg/mL (P < 0.01). In addition, it was found that BQ123, a specific ETA receptor antagonist, obviously decreased the VSMC DNA synthesis induced byQl Yongfen, BU Dingfang, YANG Jun, ZHANG Zhaokang, NIU Dadi, SHI Yanrong, ZHANG Zhenghao, TANG Chaoshu & DU JunbaoInstitute of Cardiovascular Diseases, The First Hospital of Peking University, Beijing 100083, China Department of Physiology, Health Science 2002Chinese Science Bulletin2002,47,12:0
10Adrenomedullin inhibits the endothelin production induced by urotensin Ⅱ in rat vascular smooth muscle cells显示文摘The aim of this study was to observe the effects of adrenomedullin (ADM) on endothelin (ET) production induced by urotensin Ⅱ (UⅡ) in rat vascular smooth muscle cells (VSMCs). Cultured VSMCs which were incubated with UⅡ (10-8 mol/L) and with various concentrations of ADM were used to measure the VSMCs 3H-TdR incorporation, the activity of extracellular signal-regulated kinase (ERK), the amount of ET mRNA and ET production in VSMCs. In this work we found that incubation with UⅡ (10-8 mol/L) increased obviously the amount of ET mRNA in VSMCs and ET production in medium, however, co-incubation with ADM (10-10-10-8 mol/L) and UⅡ(10-8 mol/L) reduced the amount of ET mRNA by 15%, 24% and 45% (P< 0.01) respectively, compared with UⅡ alone. The content of ET in medium was 14.13, 11.38 and 11.00 pg/mL. ADM alone (10-8 mol/L) had no effect on ET production in VSMCs. UⅡ (10-8 mol/L) promoted the 3H-TdR incorporation and activity of ERK in VSMCs. ADM inhibited VSMCs 3H-TdR incorporation and activation ofQl Yongfen BU Dingfang YANG Jun ZHANG Zhaokang SHI Yanrong PANG Yongzheng TANG Chaoshu 2002Chinese Science Bulletin2002,47,17:0
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