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| 1 | Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum显示文摘典型药用的植物的主要成分,蓼 multiflorum (用汉语的 Heshouwu ) ,那导致特质的肝损害仍然保持不清楚。我们的以前的工作证明了有 lipopolysaccharide (LPS ) 的无毒的剂量和 Heshouwu 的治疗学的剂量的 cotreatment 能在老鼠导致肝损害,而独唱治疗不能导致看得见的损害。在现在的工作,用成分大美人和敲门在里面策略,我们发现 Heshouwu 的乙醇醋酸盐(EA ) 摘录在对待 LPS 的老鼠显示了可比较的特质的 hepatotoxicity 到整个摘录。结果显示血浆丙氨酸 aminotransferase, aspartate aminotransferase,和肝 histologic 的重要举起变化,而另外的分开的部分没能导致肝损害。有另外的分开的部分的 EA 摘录的混合在对待 LPS 的老鼠导致了可比较的特质的 hepatotoxicity 到整个摘录。化学分析进一步揭示了那 2,3,5,4-tetrahydroxy trans-stilbene-2-O -- 配糖物(trans-SG ) 和它的 cis 异构体是在 EA 的二主要混合物摘录。而且,孤立的 cis- ,并且不它的 trans 异构体,显示的可比较的特质的 hepatotoxicity 到在对待 LPS 的老鼠的 EA 摘录。cis-SG 的更高的内容从与收集的将军相比与 Heshouwu 联系的实际的肝沉醉病人在 Heshouwu 白酒或准备被检测样品。另外,血浆 metabolomics 分析证明 cis-SG-disturbing 充实显著地不同于的小径在对待 LPS 的老鼠的 trans-SG。所有这些结果建议 cis-SG 仔细与 Heshouwu 的特质的 hepatotoxicity 被联系。认为 trans-SG 的 cis-trans 异构化被紫外光或日光调停,我们的调查结果为在药发现控制 photoisomerization 并且为 Heshouwu 和芪相关的药的临床的使用用作参考。 | Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu Huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang | 2017 | Frontiers of Medicine2017，11，2： | 41 |
| 2 | Review on the Research and Practice of Deep Learning and Reinforcement Learning in Smart Grids显示文摘Smart grids are the developmental trend of power systems and they have attracted much attention all over the world.Due to their complexities,and the uncertainty of the smart grid and high volume of information being collected,artificial intelligence techniques represent some of the enabling technologies for its future development and success.Owing to the decreasing cost of computing power,the profusion of data,and better algorithms,AI has entered into its new develop-mental stage and AI 2.0 is developing rapidly.Deep learning(DL),reinforcement learning(RL)and their combination-deep reinforcement learning(DRL)are representative methods and relatively mature methods in the family of AI 2.0.This article introduces the concept and status quo of the above three methods,summarizes their potential for application in smart grids,and provides an overview of the research work on their application in smart grids. | Dongxia Zhang Xiaoqing Han Chunyu Deng | 2018 | CSEE Journal of Power and Energy Systems2018，4，3： | 44 |
| 3 | Immunological synergistic mechanisms of trans-/cis-stilbene glycosides in Heshouwu-related idiosyncratic liver injury显示文摘Heshouwu is a traditional non-toxic Chinese medicine commonly used in the clinical setting;however,clinical cases of Heshouwu-induced hepatotoxicity have been frequently reported^([1]).Pharmacoepidemiological studies have found that Heshouwu-induced liver injury occurs only in a small fraction of individuals taking the drug;these patients presented with the typ- | Lanzhi He Ping Yin Yakun Meng Jinfa Tang Tingting He Ming Niu Yuming Guo Yun Zhu Jing Jing Chunyu Li Zhijie Ma Jiabo Wang Zhaofang Bai Xiaohe Xiao | 2017 | Science Bulletin2017，62，11： | 29 |
| 4 | Synchronization of two coupled exciters in a vibrating system of spatial motion显示文摘纸建议调查二的同步的一条分析途径在空间运动的一个颤动的系统联合了 exciters。为二 exciters 的平均尖速度介绍骚乱参数,我们推出二 exciters,联合矩阵的惯性在是对称的尖速度的非维的联合方程并且联合矩阵的僵硬在一个非反响的颤动系统是反对称的。阶段角度的联合余弦效果将引起对二台马达起作用限制二 exciters 之间的阶段差别的增加以及在跑期间支撑它二 exciters 的对称的转矩的动态典型表演处理的联合的分析。它身体上解释二 exciters 的自我同步的怪癖。颤动的阶段角度的余弦效果由每 exciter 愿望减少使它惯性的时刻激动。每 exciter 的惯性的剩余时刻代表它惯性的相对时刻。 exciters 是二 exciters 的惯性的相对非维的时刻都比乘他们的产品的零和四伟大的二的同步的稳定性条件比他们阶段角度的联合余弦效果的系数的平方大,它等价于联合矩阵的惯性是积极的明确并且所有它的元素是积极的。数字结果证明颤动的系统的结构能保证同步操作的稳定性条件。关键词频率俘获-稳定性-同步-颤动的系统-振动同步传播工程被辽宁省学院科学和研究( 2008S095 )支持,中国的国家自然科学基础的关键工程( 50535010 , 50805020 )并且中国( 2007AA04Z442 )的高技术研究和开发节目。 | Chunyu Zhao Hongtao Zhu Yimin Zhang Bangchun Wen | 2010 | Acta Mechanica Sinica2010，26，3： | 25 |
| 5 | Rhizobacterium Bacillus amyloliquefaciens Strain SQRT3-Mediated Induced Systemic Resistance Controls Bacterial Wilt of Tomato显示文摘Tomato bacterial wilt caused by Ralstonia solanacearum seriously threats tomato growth in tropical and temperate regions around the world.This study reported an antagonistic bacterial strain, Bacillus amyloliquefaciens strain SQRT3, isolated from the rhizosphere soil of tomato plants, which strongly inhibited in vitro growth of pathogenic R.solanacearum.The suppression of tomato bacterial wilt by strain SQRT3 was demonstrated under greenhouse conditions.Additionally, induced systemic resistance(ISR) in tomato as one of the potential disease suppression mechanisms was investigated in the plants inoculated with the isolated bacterial strain SQRT3.The results showed that strain SQRT3 applied with R.solanacearum by drenching significantly reduced tomato bacterial wilt by 68.1% biocontrol efficiency(BE) and suppressed the R.solanacearum populations in the rhizosphere soil compared to the control only drenched with R.solanacearum.The BE of the isolated bacterial strain SQRT3 against tomato wilt increased to 84.1%by root-dipping.Tomato plants treated with both strain SQRT3 and R.solanacearum showed increases in activities of peroxidase and polyphenol oxidase compared with other treatments.The application of strain SQRT3 reduced membrane lipid peroxidation in tomato leaves.The expressions of marker genes for jasmonic acid-and salicylic acid-dependent signaling pathways were faster and stronger in tomato plants treated with both strain SQRT3 and R.solanacearum than in plants treated with either R.solanacearum or strain SQRT3 alone.Collectively, the findings indicated that strain SQRT3 can effectively control tomato wilt. | LI Chunyu HU Weicong PAN Bin LIU Yan YUAN Saifei DING Yuanyuan LI Rong ZHENG Xinyan SHEN Biao SHEN Qirong | 2017 | Pedosphere2017，27，6： | 18 |
| 6 | Responses of Soil Enzyme Activities and Microbial Community Composition to Moisture Regimes in Paddy Soils Under Long-Term Fertilization Practices显示文摘The effects of fertilization on activity and composition of soil microbial community depend on nutrient and water availability;however,the combination of these factors on the response of microorganisms was seldom studied.This study investigated the responses of soil microbial community and enzyme activities to changes in moisture along a gradient of soil fertility formed within a long-term(24 years)field experiment.Soils(0–20 cm)were sampled from the plots under four fertilizer treatments:i)unfertilized control(CK),ii)organic manure(M),iii)nitrogen,phosphorus,and potassium fertilizers(NPK),and iv)NPK plus M(NPK+M).The soils were incubated at three moisture levels:constant submergence,five submerging-draining cycles(S-D cycles),and constant moisture content at 40%water-holding capacity(low moisture).Compared with CK,fertilization increased soil organic carbon(SOC) by 30.1%–36.3%,total N by 27.3%–38.4%,available N by 35.9%–56.4%,available P by 61.4%–440.9%,and total P by 28.6%–102.9%.Soil fertility buffered the negative effects of moisture on enzyme activities and microbial community composition.Enzyme activities decreased in response to submergence and S-D cycles versus low moisture.Compared with low moisture,S-D cycles increased total phospholipid fatty acids(PLFAs)and actinomycete,fungal,and bacterial PLFAs.The increased level of PLFAs in the unfertilized soil after five S-D cycles was greater than that in the fertilized soil.Variations in soil microbial properties responding to moisture separated CK from the long-term fertilization treatments.The coefficients of variation of microbial properties were negatively correlated with SOC,total P,and available N.Soils with higher fertility maintained the original microbial properties more stable in response to changes in moisture compared to low-fertility soil. | LI Weitao WU Meng LIU Ming JIANG Chunyu CHEN Xiaofen Yakov KUZYAKOV Jorg RINKLEBE LI Zhongpei | 2018 | Pedosphere2018，28，2： | 16 |
| 7 | Control theorem of a universal uniform-rotating magnetic vector for capsule robot in curved environment显示文摘For realizing non-contact steering swimming of a capsule robot in curved environment filled with viscous liquid,based on spatial orthogonal superposition theorem of alternating magnetic vectors,an innovative physical method is proposed,which employs three-axis orthogonal square Helmholtz coils fed with three phase sine currents to create a universal uniform magnetic spin vector as energy source.According to the antiphase sine current superposition theorem generalized in this paper,an effective control method for successively adjusting the orientation and the rotating direction of the universal magnetic spin vector is proposed.For validating its feasibility and controllability,three-axis Helmholtz coils,power source and an innovative capsule robot prototype were manufactured,experiments were conducted in both spiral pipe and animal intestine.It was demonstrated that the orientation and the rotational direction of the universal uniform-magnetic spin vector can be adjusted successively through digital control and steering swimming of the capsule robot in spiral intestine can be achieved successfully.The breakthrough of the universal rotating uniform-magnetic vector will push forward the development of modern physics and biomedical | ZHANG YongShun WANG Na DU ChunYu SUN Ying WANG DianLong | 2013 | Science China(Technological Sciences)2013，56，2： | 16 |
| 8 | Clinical Observation of Transepithelial Corneal Collagen Cross-linking by Iontophoresis of Riboflavin in Treatment of Keratoconus显示文摘Purpose: To evaluate the efficacy and safety of transepithelial collagen cross-linking by iontophoretic delivery of riboflavin in treatment of progressive keratoconus.Methods:.Eleven patients(15 eyes) with progressive keratoconus were enrolled. After 0.1% riboflavin-distilled water solution was deliveried via transepithelial iontophpresis for 5 min with 1 m A current, and ultraviolet radiation(370 nm,.3 m W /cm2) was performed at a 1.5 cm distance for 30 min. The follow up were 6 months in all eyes. The uncorrected visual acuity, corrected visual acuity,endothelial cell counting, corneal thickness,.intraocular pressure, corneal curvature, corneal topography,.OCT and corneal opacity before and 6-month after surgery were analyzed.Results: At 6 month postoperatively, mean uncorrected visual acuity and corrected visual acuity changed from 0.36 to 0.30 and from 0.42 to 0.57 without statistical significance..The mean value of each index of corneal curvature declined without statistical significance.Kmax value dereased from 60.91 to59.91, and the astigmatism declined from 3.86 to 3.19. Central corneal thickness decreased from 460.93 μm to 455.40μm,.and thinnest corneal thickness declined from 450.87 μm to 440.60 μm with no statistical significance..Intraocular pressure was significantly elevated from 10.85 mm Hg to 12.62 mm Hg. Endothelial cell count did not change significantly. No corneal haze occurred. Mean depth of corneal demarcation line was 288.46 μm at 1 month postoperatively..Conclusion:.Transepithelial corneal collagen cross-linking by iontophoresis is effective and safe in the treatment of progressive keratoconus, and yields stable clinical outcomes during 6-month follow up..However,.long-term follow up is urgently required. | Na Li Zhengjun Fan Xiujun Peng Xu Pang Chunyu Tian | 2014 | Eye Science2014，29，3： | 15 |
| 9 | Cadmium accumulation and tolerance of two castor cultivars in relation to antioxidant systems显示文摘To investigate the effects of Cd on tolerance and antioxidant activities of castor, two different castor(Ricinus communis L.) cultivars(Zibo No. 5 and Zibo No. 8) were used for a hydroponic experiment(0, 1 and 2 mg/L Cd) and a pot experiment using Cd-contaminated soil(34 mg/kg) with the addition of ethylenedinitrilotetraacetic acid(EDTA). The results indicated that there were significant differences between the two cultivars with respect to Cd uptake in shoots(113–248 mg/kg for Zibo No. 5 and 130–288 mg/kg Zibo No. 8), biomass tolerance indexes(64.9%–74.6% for Zibo No. 5 and 80.1%–90.9% for Zibo No. 8) in the hydroponic experiment and survival rates(0% for Zibo No. 5 and 100% for Zibo No. 8)determined by the addition of EDTA in the pot experiment, suggesting that Zibo No. 8 has higher tolerance than Zibo No. 5. Moreover, the castor cultivars have low bioconcentration factors(4.80% for Zibo No. 5 and 5.43% for Zibo No. 8) and low translocation factors(<1%).Consequently, Zibo No. 8 can participate in Cd phytostabilization in highly Cd-polluted areas. The results indicated that glutathione(GSH) as a non-enzymatic antioxidant, and antioxidant enzymes including superoxide dismutase(SOD), catalase(CAT) and guaiacol peroxidase(GPX), were cultivar- and dose-dependent. The higher tolerance of Zibo No. 8compared with Zibo No. 5 can be attributed to the higher GSH levels in the root and higher GPX activity in the leaf. | Hanzhi Zhang Qingjun Guo Junxing Yang Tongbin Chen Guangxu Zhu Marc Peters Rongfei Wei Liyan Tian Chunyu Wang Deyun Tan Jie Ma Gangming Wang Yingxin Wan | 2014 | Journal of Environmental Sciences2014，26，10： | 15 |
| 10 | Integrating TM and Ancillary Geographical Data with Classification Trees for Land Cover Classification of Marsh Area显示文摘The main objective of this research is to determine the capacity of land cover classification combining spec- tral and textural features of Landsat TM imagery with ancillary geographical data in wetlands of the Sanjiang Plain, Heilongjiang Province, China. Semi-variograms and Z-test value were calculated to assess the separability of grey-level co-occurrence texture measures to maximize the difference between land cover types. The degree of spatial autocorrelation showed that window sizes of 3×3 pixels and 11×11 pixels were most appropriate for Landsat TM im- age texture calculations. The texture analysis showed that co-occurrence entropy, dissimilarity, and variance texture measures, derived from the Landsat TM spectrum bands and vegetation indices provided the most significant statistical differentiation between land cover types. Subsequently, a Classification and Regression Tree (CART) algorithm was applied to three different combinations of predictors: 1) TM imagery alone (TM-only); 2) TM imagery plus image texture (TM+TXT model); and 3) all predictors including TM imagery, image texture and additional ancillary GIS in- formation (TM+TXT+GIS model). Compared with traditional Maximum Likelihood Classification (MLC) supervised classification, three classification trees predictive models reduced the overall error rate significantly. Image texture measures and ancillary geographical variables depressed the speckle noise effectively and reduced classification error rate of marsh obviously. For classification trees model making use of all available predictors, omission error rate was 12.90% and commission error rate was 10.99% for marsh. The developed method is portable, relatively easy to im- plement and should be applicable in other settings and over larger extents. | NA Xiaodong ZHANG Shuqing ZHANG Huaiqing LI Xiaofeng YU Huan LIU Chunyue | 2009 | Chinese Geographical Science2009，19，2： | 14 |
| 11 | Observation of mega-dune evaporation after various rain events in the hinterland of Badain Jaran Desert, China显示文摘The formation mechanisms of the mega-dunes and lakes in the hinterland of Badain Jaran Desert,China,is the focus of extensive academic research in the field of geoscience,and an often debated topic is whether atmospheric precipitation on the mega-dune can infiltrate to recharge groundwater.In the present study,the probability distribution functions and the return period analysis of extreme daily precipitation based on long-term precipitation records for the southern margin of Badain Jaran Desert and 2-year observation of hinterland precipitation were used to classify precipitation in the desert region.The data of automatic weather station and eddy covariance system in the desert hinterland were used to analyze evaporation on the mega-dune surface after various rain events.The results showed that the rain events in the desert could be divided into three categories.The first is conventional precipitation(CP),which is below 5 mm,accounting for roughly 90%of all rain events in the desert.The second and third categories are ordinary annual maximum(OAM)and extreme precipitation(EP),in which precipitation is roughly 20 mm and more than 40 mm,respectively.The atmospheric precipitation of CP and OAM evaporated from the megadune surface in 1–3 days and 3–4 weeks,respectively.Following an EP event,the mega-dune evaporation was negatively influenced by the upper dry sand layer,and a lengthy period was required for its complete removal.The accumulative evaporation and accumulative precipitation of all three types of rain events indicated that local atmospheric precipitation had no significant contribution to recharging the groundwater system in the hinterland of Badain Jaran Desert.This research will benefit comprehensive elucidation of the formation mechanism of lakes in the hinterland of Badain Jaran Desert. | Ning Ma Naiang Wang Liqiang Zhao Zhenyu Zhang Chunyu Dong Shiping Shen | 2014 | Chinese Science Bulletin2014，59，2： | 14 |
| 12 | Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing显示文摘Tracing the emergence of the first hematopoietic stem cells(HSCs)in human embryos,particularly the scarce and transient precursors thereof,is so far challenging,largely due to the technical limitations and the material rarity.Here,using single-cell RNA sequencing,we constructed the first genome-scale gene expression landscape covering the entire course of endothelial-to-HSC transition during human embryogenesis.The transcriptomically defined HSC-primed hemogenic endothelial cells(HECs)were captured at Carnegie stage(CS)12-14 in an unbiased way,showing an unambiguous feature of arterial endothelial cells(ECs)with the up-regulation of RUNX1,MYB and ANGPTL Importantly,subcategorizing CD34+CD45-ECs into a CD44+population strikingly enriched HECs by over 10-fold.We further mapped the developmental path from arterial ECs via HSC-primed HECs to hematopoietic stem progenitor cells,and revealed a distinct expression pattern of genes that were transiently over-represented upon the hemogenic fate choice of arterial ECs#including EMCN,PROCR and RUNX1T1.We also uncovered another temporally and molecularly distinct intra-embryonic HEC population,which was detected mainly at earlier CS 10 and lacked the arterial feature.Finally,we revealed the cellular components of the putative aortic niche and potential cellular interactions acting on the HSCprimed HECs.The cellular and molecular programs that underlie the generation of the first HSCs from HECs in human embryos,together with the ability to distinguish the HSC-primed HECs from others,will shed light on the strategies for the production of clinically useful HSCs from pluripotent stem cells. | Yang Zeng Jian He Zhijie Bai Zongcheng Li Yandong Gong Chen Liu Yanli Ni Junjie Du Chunyu Ma Lihong Bian Yu Lan Bing Liu | 2019 | Cell Research2019，29，11： | 14 |
| 13 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 14 | Synchronization of the four identical unbalanced rotors in a vibrating system of plane motion显示文摘A new mechanism is proposed to implement the synchronization of the four unbalanced rotors in a vibrating system, which consists of a main rigid frame (MRF) and two accessorial rigid frames (ARF). An analytical approach is developed to study the coupling dynamic characteristics of the four unbalanced rotors, which converts the problem of synchronization of the four unbalanced rotors into the existence and the stability of zero solutions for the non-dimensional differential equations of the angular velocity disturbance parameters (NDDEDP). The stability of zero solutions of the NDDEDP is decomposed into that of its generalized system and a system of the three first order differential equations for the disturbance parameters of the phase differences. The coupling dynamic characteristic of the four unbalanced rotors includes the inertia coupling, the stiffness coupling of angular velocity and the load torque coupling. The non-dimensional inertia coupling matrix is symmetric, the non dimensional matrix of the stiffness coupling of angular velocity is antisymmetric and its diagonal elements are all negative. Hence, the general system of the NDDEDP automatically satisfies the generalized Lyapunov equations when the non-dimensional inertia coupling matrix is positive definite and its elements are all positive. Using Routh-Hurwitz criterion the condition of stability of differential equations for the disturbance parameters of the phase differences is obtained. The load torque coupling makes the vibrating system have the dynamic characteristic of selecting motions and self-synchronization of the four unbalanced rotors arises from the dynamic characteristic of selecting motion of the vibrating system. When the two coefficients of coupling cosine effect of phase angles are all greater than 0 and the three indexes of synchronization are all far greater than 1, the vibrating system can implement an elliptical motion of the main rigid frame required in engineering. Numeric results show that the structural parameters of the proposed mechanism can guarantee the non-dimensional inertia matrix to be always positive definite. Computer simulation is carried out to verify the results of the theoretical investigation. | ZHAO ChunYu, WEN BangChun & ZHANG XueLiang School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110004, China | 2010 | Science China(Technological Sciences)2010，53，2： | 12 |
| 15 | A point mutation resulting in a 13 bp deletion in the coding sequence of Cldf leads to a GA-deficient dwarf phenotype in watermelon显示文摘The dwarf architecture is an important and valuable agronomic trait in watermelon breeding and has the potential to increase fruit yield and reduce labor cost in crop cultivation.However,the molecular basis for dwarfism in watermelon remains largely unknown.In this study,a recessive dwarf allele(designated as Cldf(Citrullus lanatus dwarfism))was fine mapped in a 32.88 kb region on chromosome 09 using F2 segregation populations derived from reciprocal crossing of a normal line M08 and a dwarf line N21.Gene annotation of the corresponding region revealed that the Cla015407 gene encoding a gibberellin 3β-hydroxylase functions as the best possible candidate gene for Cldf.Sequence analysis showed that the fourth polymorphism site(a G to A point mutation)at the 3′AG splice receptor site of the intron leads to a 13 bp deletion in the coding sequence of Cldf in dwarf line N21 and thus results in a truncated protein lacking the conserved domain for binding 2-oxoglutarate.In addition,the dwarf phenotype of Cldf could be rescued by exogenous GA3 application.Phylogenetic analysis suggested that the small multigene family GA3ox(GA3 oxidase)in cucurbit species may originate from three ancient lineages in Cucurbitaceae.All these data support the conclusion that Cldf is a GA-deficient mutant,which together with the cosegregated marker can be used for breeding new dwarf cultivars. | Chunhua Wei Chunyu Zhu Liping Yang Wei Zhao Rongxue Ma Hao Li Yong Zhang Jianxiang Ma Jianqiang Yang Xian Zhang | 2019 | Horticulture Research2019，6，1： | 12 |
| 16 | Multi-scale analysis to uncover habitat use of red-crowned cranes: Implications for conservation显示文摘 | Chunyue LIU Hongxing JIANG Shuqing ZHANG Chunrong LI Yunqiu HOU Fawen QIAN | 2013 | Current Zoology2013，59，5： | 12 |
| 17 | Drop test and crash simulation of a civil airplane fuselage section显示文摘Crashworthiness of a civil airplane fuselage section was studied in this paper. Firstly, the failure criterion of a rivet was studied by test, showing that the ultimate tension and shear failure loads were obviously affected by the loading speed. The relations between the loading speed and the average ultimate shear, tension loads were expressed by two logarithmic functions. Then, a vertical drop test of a civil airplane fuselage section was conducted with an actual impact velocity of6.85 m/s, meanwhile the deformation of cabin frame and the accelerations at typical locations were measured. The finite element model of a main fuselage structure was developed and validated by modal test, and the error between the calculated frequencies and the test ones of the first four modes were less than 5%. Numerical simulation of the drop test was performed by using the LS-DYNA code and the simulation results show a good agreement with that of drop test. Deforming mode of the analysis was the same as the drop test; the maximum average rigid acceleration in test was 8.81 g while the calculated one was 9.17 g, with an error of 4.1%; average maximum test deformation at four points on the front cabin floor was 420 mm, while the calculated one was 406 mm, with an error of 3.2%; the peak value of the calculated acceleration at a typical location was 14.72 g, which is lower than the test result by 5.46%; the calculated rebound velocity result was greater than the test result 17.8% and energy absorption duration was longer than the test result by 5.73%. | Liu Xiaochuan Guo Jun Bai Chunyu Sun Xiasheng Mou Rangke | 2015 | Chinese Journal of Aeronautics2015，28，2： | 12 |
| 18 | Direction of arrival estimation and signal recovery based on single snapshot compressed sensing in frequency domain显示文摘Direction of arrival(DOA) estimation and signal recovery is the base of the underwater target localization,tracking and recognition.Based on the compressed sensing theory,a method for DOA estimation and source signal recovery is proposed using the single snapshot processing of the received array signal in frequency domain.The received array signal are transformed to frequency domain,and the single snapshot data in frequency domain are regarded as the measured data of the compressed sensing.According to the frequency,searching orientation and array manifold,the overcomplete array manifold is constructed as the sensing matrix of the compressed sensing.Both the target signal and power of the searching orientation are estimated by the basis pursuit method to complete DOA estimation and signal recovery.Simulation results show that the proposed method has a number of advantages over the minimum variance distortionless response(MVDR) method,including improved robustness to noise,fewer requirement in number of sensors and snapshots.And the correlation coefficient of the signal reaches up to 0.89.Experiment results in real environments verify that the proposed method performs more effectively in the detection of weak targets than the MVDR method and can be applied to real sonar system. | KANG Chunyu LI Qianyan ZHANG Xinhua LI Jun | 2016 | Chinese Journal of Acoustics2016，35，2： | 10 |
| 19 | FLECH:A Danish market solution for DSO congestion management through DER flexibility services显示文摘Future electric power systems will face new operational challenges due to the high penetration of distributed energy resources(DERs).In Denmark,distribution system operator(DSO)expects a significant congestion increased in distribution grids.In order to manage these congestions and mobilize the DERs as economically efficient as possible in the future distribution grid,the brand new notion of flexibility clearing house(FLECH)is proposed in this paper.With the aggregator-based offers,the proposed FLECH market has the ability to promote small scale DERs(upto 5 MW)for actively participating in trading flexibility services,which are stipulated accommodating the various requirements of DSO.Accordingly,the trading setups and processes of the FLECH market are also illustrated in detail.A quantitative example is utilized to illustrate the formulation and classification of flexibility services provided by the DERs in the proposed FLECH market. | Chunyu ZHANG Yi DING Niels Christian NORDENTOFT Pierre PINSON JacobØSTERGAARD | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，2： | 10 |
| 20 | Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity显示文摘Psoraleae Fructus(PF)is a well-known traditional herbal medicine in China,and it is widely used for osteoporosis,vitiligo,and other diseases in clinical settings.However,liver injury caused by PF and its preparations has been frequently reported in recent years.Our previous studies have demonstrated that PF could cause idiosyncratic drug-induced liver injury(IDILI),but the mechanism underlying its hepatotoxicity remains unclear.This paper reports that bavachin isolated from PF enhances the specific stimuli-induced activation of the NLRP3 inflammasome and leads to hepatotoxicity.Bavachin boosts the secretion of IL-ip and caspase-1 caused by ATP or nigericin but not those induced by poly(I:C),monosodium urate crystal,or intracellular lipopolysaccharide.Bavachin does not affect AIM2 or NLRC4 inflammasome activation.Mechanistically,bavachin specifically increases the production of nigericin-induced mitochondrial reactive oxygen species among the most important upstream events in the activation of the NLRP3 inflammasome.Bavachin increases the levels of aspartate transaminase and alanine aminotransferase in serum and hepatocyte injury accompanied by the secretion of IL-ip via a mouse model of lipopolysaccharide-mediated susceptibility to IDILI.These results suggest that bavachin specifically enhances the ATP-or nigericin-induced activation of the NLRP3 inflammasome.Bavachin also potentially contributes to PF-induced idiosyncratic hepatotoxicity.Moreover,bavachin and PF should be evaded among patients with diseases linked to the ATP-or nigericin-mediated activation of the NLRP3 inflammasome,which may be a dangerous factor for liver injury. | Nan Qin Guang Xu Yan Wang Xiaoyan Zhan Yuan Gao Zhilei Wang Shubin Fu Wei Shi Xiaorong Hou Chunyu Wang Ruisheng Li Yan Liu Jiabo Wang Haiping Zhao Xiaohe Xiao Zhaofang Bai | 2021 | Frontiers of Medicine2021，15，4： | 9 |
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