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| 1 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012，1，1： | 2 |
| 2 | Cloning of porcine NRAMP1 and its induction by lipopolysaccharide,tumor necrosis factor alpha,and interleukin-1beta:Role of CD14 and mitogen-activated protein kinases显示文摘 | Zhang G Wu H Ross C R Minton J E and Blecha F | | 0，，03： | 1 |
| 3 | Escherichia coli heat-labile enterotoxin promotes protective Thl7 responses against infection by driving innate IL-1 and IL-23 production显示文摘 | Brereton C F Sutton C E Ross P J | 2011 | J Immunol2011，186，10： | 1 |
| 4 | Neurodegenerative actions of interleukin-1 in the rat brain are mediated through increases in seizure activity显示文摘 | Patel H C Ross F M Heenan L E | 2006 | Journal of Neuroscience Research2006，83，3： | 1 |
| 5 | Chemoattractant properties of PR-39,a neutrophil antibacterial peptide显示文摘 | Huang H J Ross C R Blecha F | 1997 | Leukoc Biol1997，61，： | 1 |
| 6 | Surface-enhanced Infrared Spectroscopy 显示文摘 | Aroca R F Ross D J Domingo C | 2004 | Appl Spectrosc2004，58，： | 1 |
| 7 | Expression of bFGF, VEGF and c-met and their correlation with microvessel density and progression in prostate carcinoma 显示文摘 | Strohmeyer D Strauss F Rossing C | 2004 | Antieancer Res2004，24，3： | 1 |
| 8 | Production infection by driving innate IL-1 and IL-23 promotes protective Thl7 responses against heat-labile entero- toxin Escherichia coli 显示文摘 | Brereton C F Sutton C E Ross P J | 2011 | J Immunol2011，186，10： | 1 |
| 9 | Knowledge management in research and development显示文摘 | Armbrecht Jr.F M Ross Chappelow C C Farris G F | | 0，，04： | 1 |
| 10 | Expression of bFGF,VEGF and c-met and their correlation with microvessel density and progression in prostate carcinoma显示文摘 | STROHMEYER D STRAUSS F ROSSING C | 2004 | Anti Cancer Res2004，24，3： | 1 |
| 11 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 12 | A conceptual design of an underwater vehicle 显示文摘 | ROSS C T F | 2006 | Ocean Engineering2006，33，16： | 1 |
| 13 | Experimental constraints on the depth of olivine metastability in subducting lithosphere 显示文摘 | Mosenfelder J L Marton F C Ross C R | 2001 | Physics of the Earth and Planetary Interiors2001，127，： | 1 |
| 14 | HAPl-huntingtin interac- tions do not contribute to the molecular pathology in Hnntingtin's disease transgenic mice 显示文摘 | Bertaux F Sharp A H Ross C A | 1998 | FEBS Lett1998，426，2： | 1 |
| 15 | Lidar sampling for large-area forest characterization: A re- view显示文摘 | Michael A Wulder Joanne C White Ross F Nelson | 2012 | Remote Sensing of Environment2012，，121： | 1 |
| 16 | Effect of ex situ treatments with SO2 on the activity of a low loading silver-alumina catalyst for the selective reduction of NO and NO2 by propene 显示文摘 | Meunier F C Ross J R H | 2000 | Appl Catal B2000，24，1： | 1 |
| 17 | In vitro evaluation of the pollen extract cernitin T60, in the regulation of prostrate cell growth 显示文摘 | HABIB F K ROSS M BUCK A C | 1990 | British Journal of Urology1990，66，： | 1 |
| 18 | Adherence of Myco?plasma hyopnemnoniae to cell monolayers显示文摘 | Zielinsli G C Young T Ross R F et a1 | 1990 | Am J Vet Res1990，51，3： | 1 |
| 19 | Adherence of Mycoplasma hyopneu?moniae to porcine ciliated respiratory tract cells显示文摘 | Zielinski G C T Ross R F | 1993 | Am J Vet Res1993，54，8： | 1 |
| 20 | Fermented functional foods based on probiotics and their biogenic metabolites显示文摘 | STANTON C ROSS R P FITZGERALD G F | 2005 | Current Opinion in Biotechnology2005，16，2： | 1 |
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