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| 1 | Tertiary lymphoid structures in cancer – considerations for patient prognosis显示文摘Tertiary lymphoid structures(TLS)are ectopic lymphoid formations that form within nonlymphoid tissue.They share structural and functional characteristics with secondary lymphoid structures such as lymph nodes and can contain B-cell follicles and germinal centers surrounded by a T-cell region.TLS have been described in several types of cancers and are usually associated with positive patient outcomes.However,TLS differ vastly in cellular composition and location within tissue types.In this review,we discuss factors confounding the interpretation of the evidence for a prognostic role for TLS in cancer and frame these factors in the context of translation to regular clinical use. | Luis Munoz-Erazo Janet L.Rhodes Valentine C.Marion Roslyn A.Kemp | 2020 | Cellular & Molecular Immunology2020，17，6： | 11 |
| 2 | The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1显示文摘 | Susan D.Thompson MarcSudman Paula S.Ramos Miranda C.Marion MaryRyan MonicaTsoras TraceyWeiler MichaelWagner MehdiKeddache J. PeterHaas CorneliaMueller SampathPrahalad JohnBohnsack Carol A.Wise MarilynnPunaro DongpingZhang Carlos D.Rosé Mary E.Comeau Jasmi | 2010 | Arthritis & Rheumatism2010，，11： | 1 |
| 3 | The modifying influence of HLA classⅡDQB1^(*)06:02 on the Streptococcus and clinical phenotype correlation among anti-Ro+mothers of children with neonatal lupus显示文摘The genus Streptococcus,a gram-positive bacterium,con-tains species associated with immune activation at morbid outcomes,including scarlet fever,endocarditis,meningitis,and rheumatic fever.In both stool and saliva,there is a pos-itive correlation between Streptococcus abundance and Sjogren’s syndrome(SS)and systemic lupus erythematosus(SLE). | Robert M.Clancy Carla J.Guthridge Miranda C.Marion Joel Guthridge Timothy D.Howard Peter M.Izmirly Mala Masson Jill P.Buyon Judith A.James Carl D.Langefeld | 2023 | Genes & Diseases2023，10，4： | 0 |
| 4 | Investigating the use of an ionic liquid for rare earth mineral flotation显示文摘Common collectors for rare earth mineral(REM) flotation,which include carboxylates and hydroxamates,face problems such as being non-selective and sensitive to impurity ions.A type of ionic liquid(IL),tetraethylammonium mono-(2-ethylhexyl)2-ethylhexyl phosphonate([N_(2222)][EHEHP]),has been investigated previously for rare earth elements(REE) solvent extraction,and was proven to be selective and effective.In this work,[N_(2222)][EHEHP] was evaluated as a collector in bastnasite(a primary REM source for REE production) flotation for the first time.The results were compared with quartz and hematite,two common gangue minerals in REM deposits.Zeta potential measurements and Fouriertransform infrared spectroscopy(FT-IR) were completed to investigate the surface chemical properties involved in the flotation of these minerals using this collector.The findings were compared with microflotation results.FT-IR and zeta potential measurements suggest adsorption of the collector’s phosphonate group onto bastnäsite and hematite,likely through chemisorption;whereas for quartz,the minimum micro flotation recovery is likely due to no adsorption of IL on its surface.Micro flotation re sults show higher collectability of [N_(2222)] [EHEHP] for hematite than bastnasite,the latter only shows appreciable recovery at pH 5 with elevated dosage of IL(500 g/t).To achieve better separation,a two-stage flotation scheme was designed and evaluated by bench scale flotation on a synthetic mineral mixture.The concentrates and tails were analyzed by magnetic separation,and it is found that bastnasite recovery over 90% with maximum upgrade ratio 1.7 can be achieved with elevated collector dosage. | R.Li C.Marion E.R.L.Espirtu R.Multani Xiaoqi Sun K.E.Waters | 2021 | Journal of Rare Earths2021，39，7： | 0 |
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