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| 1 | Diagnostic tests for hepatitis C: Recent trends in electrochemical immunosensor and genosensor analysis显示文摘Hepatitis C is a liver disease that is transmitted through contact with the blood of an infected person. An estimated 150 million individuals worldwide have been chronically infected with the hepatitis C virus(HCV). Hepatitis C shows significant genetic variation in the global population, due to the high rate of viral RNA mutation. There are six variants of the virus(HCV genotypes 1, 2, 3, 4, 5, and 6), with 15 recorded subtypes that vary in prevalence across different regions of the world. A variety of devices are used to diagnose hepatitis C, including HCV antibody test, HCV viral load test, HCV genotype test and liver biopsy. Rapid, inexpensive, sensitive, and robust analytical devices are therefore essential for effective diagnosis and monitoring of disease treatment. This review provides an overview of current electrochemical immunosensor and genosensortechnologies employed in HCV detection.There are a limited number of publications showing electrochemical biosensors being used for the detection of HCV.Due to their simplicity,specificity,and reliability,electrochemical biosensor devices have potential clinical applications in several viral infections. | Carolina V Uliana Carla S Riccardi Hideko Yamanaka | 2014 | World Journal of Gastroenterology2014，20，42： | 2 |
| 2 | Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression显示文摘The mechanical environment is known to influence fracture healing. We speculated that connexin43(Cx43) gap junctions, which impact skeletal homeostasis, fracture healing and the osteogenic response to mechanical load,may play a role in mediating the response of the healing bone to mechanical strain. Here, we used an established rat fracture model, which uses a 2 mm osteotomy gap stabilized by an external fixator, to examine the impact of various cyclical axial loading protocols(2%, 10%, and 30% strain) on osteotomy healing. We examined the presence of Cx43 in the osteotomy-healing environment and assessed how mechanical strain modulates Cx43 expression patterns in the callus. We demonstrated that increased cyclical axial strain results in increased radiographic and histologic bone formation. In addition, we show by immunohistochemistry that Cx43 is abundantly expressed in the healing callus, with the expression most robust in samples exposed to increased cyclical axial strain. These data are consistent with the concept that an increase in Cx43 expression by mechanical load may be part of the mechanisms by which mechanical forces enhances fracture healing. | Rishi R Gupta Hyunchul Kim Yu-Kwan Chan Carla Hebert Leah Gitajn David J Yoo Robert V O’Toole Adam H Hsieh Joseph P Stains | 2015 | Bone Research2015，3，2： | 2 |
| 3 | Degradable biomaterials based on Magnesium corrosion 显示文摘 | Frank W Norbert H Carla V Smadar C Karl U K Regine W Frank F | 2008 | Current Opinion in Solid State and Materials Science2008，12，56： | 1 |
| 4 | Cellular damage and altered carbohydrate expression in P815 tumor cells induced by direct electric current: an in vitro analysis 显示文摘 | Venicio F V Carla H Marcio L R | 2000 | Bioelectromagnetics2000，21，8： | 1 |
| 5 | The exeitotoxin quinolinic acid is present and unevenly distributed in the rat brain显示文摘 | Moroni F Lombardi G Carla V | 1988 | Brain Res1988，295，： | 1 |
| 6 | Heptacoordinate tricarbonyt Mo(II) complexes as highly selective oxidation homogeneous and heterogeneous catalysts 显示文摘 | Maria V D Carla D N Pedro D V | 2008 | J Catal2008，256，2： | 1 |
| 7 | Adecrease in brain catecholamines prevents oxiracetamantagonism of the effects of scopolamine on memory andbrain acetylcholine 显示文摘 | GIOVANNINI M G SPIGNOLI G CARLA V | 1991 | Pharmacol Res1991，，24： | 1 |
| 8 | High pressure routes todimethyl carbonate from supercritical carbon dioxide显示文摘 | Neil S I Brian O Carla V | 1999 | Tetrahedron1999，55，11： | 1 |
| 9 | Calcium channel inhibitors suppress the morphine -withdrawal syndrome in rats显示文摘 | Bongianni F Carla V Moroni F | 1986 | Br J Pharmacol1986，88，3： | 1 |
| 10 | Prey versus substrate as determinants of habitat choice in a feeding shorebird 显示文摘 | FINN PAUL G CARLA P CATTERALL PETER V DRISCOLL | 2008 | Estuarine Coastal and Shelf Science2008，80，3： | 1 |
| 11 | Calcium channels inhibi-tors suppress the morphine-withdrawal syndrome in rats 显示文摘 | Bongianni F Carla V Moroni F | 1988 | Pharmacology1988，88，： | 1 |
| 12 | Shades of Impersonality: Rhetorical Positioning in the Academic Writing of ItaLian Students of English显示文摘 | Carla V | 2011 | Linguistics and Education2011，，2： | 1 |
| 13 | Determination of cationic surfacrants by capillary electrophoresis with indirect photometric detection 显示文摘 | KATJA H CARLA V GERHARD W | 1997 | Journal of Chromatography A1997，781，12： | 1 |
| 14 | Degradable biomaterials based on magnesium corrosion显示文摘 | Frank W Norbert H Carla V | 2008 | Current Opinion in Solid State and Materials Science2008，12，56： | 1 |
| 15 | Transvesical thoracoscopy: A natural orifice translumenal endoscopic approach for thoracic surgery显示文摘 | Estêv?o Lima Tiago Henriques-Coelho Carla Rolanda José M. Pêgo David Silva José L. Carvalho Jorge Correia-Pinto | 2007 | Surgical Endoscopy2007，，6： | 1 |
| 16 | Gastroduodenal and intestinal permeability in primary biliary cirrhosis显示文摘 | VINCENZA DI L CARLA V ANNA B | 2003 | European Journal of Gastroenterology & Hepatology2003，15，9： | 1 |
| 17 | Mixtures of quaternary ammonium compounds and anionic organic compounds in the aquatic environment: Elimination and biodegradability in the closed bottle test monitored by LC-MS/MS 显示文摘 | Kees V L Carla R Ton D N | 1992 | Chcmosphere1992，，24： | 1 |
| 18 | Epigenetic silencing of CRABP2 and Mx1 in head and neck tumors 1,2显示文摘 | Marilia F Rodrigo V Carla M | 2009 | Neoplasia2009，11，12： | 1 |
| 19 | Filho, Reburning and burnout simulations of natural gas for heavy oil combustion显示文摘 | Bertrana C A Carla S T Marquesa R V | 2004 | Fuel2004，，83： | 1 |
| 20 | Physical and thermal properties of potato chips during vacuum frying 显示文摘 | CARLA V YAGUA ROSANA G | 2011 | Journal of Food Engineering2011，，： | 1 |
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