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| 1 | On the use Zadeh's probabilistic definition for testing statistical hypotheses from fuzzy information显示文摘 | Casals M R Gil M A Gil P | 1986 | Fuzzy Sets and Systems1986，20，： | 4 |
| 2 | Presacral venous bleeding during mobilization in rectal cancer显示文摘AIM To analyze the anatomy of sacral venous plexus flow, the causes of injuries and the methods for controlling presacral hemorrhage during surgery for rectal cancer.METHODS A review of the databases MEDLINE? and Embase? was conducted, and relevant scientific articles published between January 1960 and June 2016 were examined. The anatomy of the sacrum and its venous plexus, as well as the factors that influence bleeding, the causes of this complication, and its surgical management were defined.RESULTS This is a review of 58 published articles on presacral venous plexus injury during the mobilization of the rectum and on techniques used to treat presacral venous bleeding. Due to the lack of cases published in the literature, there is no consensus on which is the best technique to use if there is presacral bleeding during mobilization in surgery for rectal cancer. This review may provide a tool to help surgeons make decisions regarding how to resolve this serious complication.CONCLUSION A series of alternative treatments are described; however, a conventional systematic review in which optimal treatment is identified could not be performed because few cases were analyzed in most publications. | Jose Enrique Casal Núnez Vincenzo Vigorita Alejandro Ruano Poblador Ana María Gay Fernández Maria ángeles Toscano Novella Nieves Cáceres Alvarado Lucinda Pérez Dominguez | 2017 | World Journal of Gastroenterology2017，23，9： | 4 |
| 3 | Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature显示文摘 | Mercedes Herrera Abul B.M.M.K. Islam Alberto Herrera Paloma Martín Vanesa García Javier Silva Jose M. Garcia Clara Salas Ignacio Casal Antonio García de Herreros Félix Bonilla Cristina Pe?a | 2013 | Clinical Cancer Research2013，，21： | 2 |
| 4 | Complex magnetism and magnetic structures of the metastable HoMnO3 perovskite显示文摘 | Munoz A Casals M T Alonso J A | 2001 | Inorg Chem2001，40，： | 1 |
| 5 | Preparation and electrochemical study of cerium-silica sol-gel thin films 显示文摘 | GARCIA-HERAS M JIMENEZ-MORALES A CASAL B | 2004 | Journal of Alloys and Compounds2004，380，12： | 1 |
| 6 | Accuracy of methods forfield assessment of rill and ephemeral gully erosion显示文摘 | CasalíJ Loizu J Campo M A | 2006 | Cate-na2006，67，2： | 1 |
| 7 | Obstructive sleep apnea syndrome(OSAS) in children with Class Ⅲ malocclusion:involvement of the PHOX2B gene显示文摘 | Lavezzi A M Casale V Oneda R | 2013 | Sleep and Breathing2013，17，4： | 1 |
| 8 | Inhibin A serum levels in proteinuric and nonproteinuric pregnancy-induced hypertension: Evidence for placental involvement in gestational hypertension显示文摘 | Casals E Gomez O Aibar C Cararach V Alonso PL Fortuny A | 2000 | Hypertens Preg2000，19，3： | 1 |
| 9 | Molecular cloning, sequencing and expression in Escherichiacoli of thecapsid protein gene from rabbit haemorrhagic disease virus (Spanishisolate AST/89)显示文摘 | Boga J A Casals R Marin M S | 1994 | J Gen Virol1994，75，： | 1 |
| 10 | Multiagent control of self-reconfigurable robots 显示文摘 | BojJnov H Casal A Hogg T | 2002 | Artificial Intelligence2002，142，： | 1 |
| 11 | Mathematical modeling of accidental gas releases显示文摘 | Montiel H Vilchez J A Casal J | 1998 | Journal of Hazardous Materials1998，59，2： | 1 |
| 12 | Repair of hypospadias complications using the previously utilized urethral plate显示文摘 | SIMMONS G R CAIN M P CASALE A J | 1999 | Urology1999，54，： | 1 |
| 13 | An experimental study of the main geometrical features of the flame in subsonic and sonic regimes显示文摘 | Palacios A Munoz M Casal J | 2008 | Environmental and Energy Engineering2008，55，1： | 1 |
| 14 | The SAPHO syn- drome revisited with an emphasis on spinal manifestations 显示文摘 | Leone A Cassar- Pullicino VN Casale R | 2015 | Skeletal Radiol2015，44，1： | 1 |
| 15 | Effect of the agitation on the adsorption and hydrolytic efficiency of cutinases on polyethylene terephthalate fibres显示文摘 | NEILL O A ARAtJJO R CASAL M | 2007 | Enzyme and Microbial Technology2007，40，7： | 1 |
| 16 | Tolerability of retreatment with omalizumab,a recombinant humanized monoclonul anti-IgE antibody,during a second ragweed pollen season in patients with seasonal allergic rhinitis显示文摘 | Nayak A Casale T Miller SD | 2003 | Allergy Asthma Proc2003，24，5： | 1 |
| 17 | Concealed penis in childhood; a spectrum of etiology and treamment 显示文摘 | Casale A J Stephen D Beck SD | 1999 | Urol1999，162，32： | 1 |
| 18 | Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability. | Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas | 2021 | Engineering2021，7，10： | 1 |
| 19 | Functional neu- roimaging in obsessive-compulsive disorder显示文摘 | Del Casale A Kotzalidis G D Rapinesi C | 2011 | Neuropsychobi- ology2011，64，2： | 1 |
| 20 | Use of chitosan for selective removal of β-lactoglobulin from whey显示文摘 | CASAL E MONTILLA A | 2006 | Jounal of Dairy Science2006，89，： | 1 |
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