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133篇 您的检索式:作者名="CHRISTOPHER D K"
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1Selecting suitable solid organ transplant donors: Reducing the risk of donor-transmitted infections显示文摘Selection of the appropriate donor is essential to a successful allograft recipient outcome for solid organ transplantation. Multiple infectious diseases have been transmitted from the donor to the recipient via transplantation. Donor-transmitted infections cause increased morbidity and mortality to the recipient. In recent years, a series of high-profile transmissions of infections have occurred in organ recipients prompt-ing increased attention on the process of improving the selection of an appropriate donor that balances the shortage of needed allografts with an approach that mitigates the risk of donor-transmitted infection to the recipient. Important advances focused on improving donor screening diagnostics, using previously excluded high-risk donors, and individualizing the selection of allografts to recipients based on their prior infection history are serving to increase the donor pool and improve outcomes after transplant. This article serves to review the relevant literature surrounding this topic and to provide a suggested approach to the selection of an appropriate solid organ transplant donor.Christopher S Kovacs Jr Christine E Koval David van Duin Amanda Guedes de Morais Blanca E Gonzalez Robin K Avery Steven D Mawhorter Kyle D Brizendine Eric D Cober Cyndee Miranda Rabin K Shrestha Lucileia Teixeira Sherif B Mossad 2014World Journal of Transplantation2014,4,2:7
2Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed.Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee 2014World Journal of Clinical Oncology2014,5,2:5
3Acute kidney injury and hepatorenal syndrome in cirrhosis显示文摘Acute kidney injury(AKI)in cirrhosis,including hepatorenal syndrome(HRS),is a common and serious complication in cirrhotic patients,leading to significant morbidity and mortality.AKI is separated into two categories,non-HRS AKI and HRS-AKI.The most recent definition and diagnostic criteria of AKI in cirrhosis and HRS have helped diagnose and prognosticate the disease.The pathophysiology behind non-HRS-AKI and HRS is more complicated than once theorized and involves more processes than just splanchnic vasodilation.The common biomarkers clinicians use to assess kidney injury have significant limitations in cirrhosis patients;novel biomarkers being studied have shown promise but require further studies in clinical settings and animal models.The overall management of non-HRS AKI and HRS-AKI requires a systematic approach.Although pharmacological treatments have shown mortality benefit,the ideal HRS treatment option is liver transplantation with or without simultaneous kidney transplantation.Further research is required to optimize pharmacologic and nonpharmacologic approaches to treatment.This article reviews the current guidelines and recommendations of AKI in cirrhosis.Kapil Gupta Abhishek Bhurwal Cindy Law Scott Ventre Carlos D Minacapelli Savan Kabaria You Li Christopher Tait Carolyn Catalano Vinod K Rustgi 2021World Journal of Gastroenterology2021,27,26:5
4Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘Christopher J L Murray Theo Vos Rafael Lozano Mohsen Naghavi Abraham D Flaxman Catherine Michaud Majid Ezzati Kenji Shibuya Joshua A Salomon Safa Abdalla Victor Aboyans Jerry Abraham Ilana Ackerman Rakesh Aggarwal Stephanie Y Ahn Mohammed K Ali Mohammad A 2012The Lancet . 2012 (9859)2012,,9859:2
5Hyper-X Post-Flight Trajectory Reconstruction显示文摘Christopher D K Paul V T Robert C B 2006Journal of Spacecraft and Rockets2006,43,1:1
6Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H 2008Plant Physiology2008,147,2:1
7Early involve ment of death associated protein kinase promoter hypermethylation in the carcinogenesis of harrett's esophageal adenocareinoma and its association with clinical progression显示文摘Doerthe K Altar A D Christopher C M 2007Ncoplasia2007,9,3:1
8Hypertonic hyperoncotic solutions reduce the release of cardiac troponin Ⅰ and S-100 after successful cardiopulmonary resuscitation in pigs 显示文摘Heiner K Christof D Christoph J 2002Anesth Analg2002,95,:1
9Human vulnerability in volcanic environments:the case of Furnas,Sa(o) Miguel,Azores显示文摘Christopher D Chester D K 1999Journal of Volcanology and Geothermal Research1999,92,:1
10Surgical treatment of vulvar vestibulitis syndrome: outcome assessment derived from a postoperative questionnaire显示文摘Goldstein AT Klingman D Christopher K 2006J Sex Med2006,3,:1
11Robust rendezvous navigation in ellip- tical orbit显示文摘Christopher D K 2006Journal of Guidance Control and Dy- namics2006,29,2:1
12Thiolate ligands for synthesis of water-soluble gold clusters显示文摘Christopher J A Pablo D J Roger D K 2005J Am Chem Soc2005,127,18:1
13Huber-based divided difference filte- ring显示文摘Christopher D K 2007Journal of Guidance Control and Dynamics2007,30,3:1
14Burnout in nurses-the relation- ship between social capital in hospitals and emotional exhaustion 显示文摘Christoph K OliverO Elke D 2010Journal 1 of Clinical Nursing2010,19,1112:1
15Radiofrequency Ablation as First-Line Treatment in Patients With Early Colorectal Liver Metastases Amenable to Surgery显示文摘Gerd Otto Christoph Düber Maria Hoppe-Lotichius Jochem K?nig Michael Heise Michael Bernhard Pitton 2010Annals of Surgery2010,,5:1
16Burnout in nurses--the relationship between social capital in hospitals and emotional exhaustion显示文摘Christoph K Oliver O Elke D 2010Journal of Clinical Nursing2010,19,1112:1
17Hyper-X post-flight trajectory reconstruction显示文摘CHRISTOPHER D K PAUL V T 2006Journal of Spacecraft and Rockets2006,43,1:1
18The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M 2008Nature2008,452,:1
19Free-radical copolymerization of styrene and m -isopropenyl- a,ar - dimethylbenzyl msoeyanate studied by ^1H-NMR kinetic experiments显示文摘Leonie B Christopher B K Thomas P D 2002J Polym Sci: Part A: Polym Chem2002,40,:1
20The complexity and robustness of metro networks 显示文摘Sybil D Christopher K 2010Physica A2010,389,36:1
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