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17篇 您的检索式:作者名="COURTNEY C W"
    题名 作者 年代 出处 被引量
1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2Surface heat treatment of EN 8 steel using a 2 kW continuous-wave CO2 laser 显示文摘Steen W M Courtney C H G 1979Metals Technol1979,6,12:1
3Evaluation of isolation methods and RNA integrity for bacterial RNA quantitation显示文摘Courtney E J Amy 0 C David K W 2008Journal of Microbiological Methods2008,75,2:1
4Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia显示文摘NICOL B REGINE W F COURTNEY C 2000J Neurosurg2000,93,:1
5Purifica- tion and immunochemistry of a soluble matrix protein of the chicken eggshell(ovocleidin 17)显示文摘Hincke M T Tsang C P W Courtney M 1995Calcified Tissue International1995,56,6:1
6Purification and immunochemistry of a soluble ma- trix protein of the chicken eggshell (ovocleidin 17 ) 显示文摘HINCKE M T TSANG C P W COURTNEY M 1995Calcified Tissue International1995,56,6:1
7Low levels of intraspecific genetic variation at a rapidly evolving chloroplast GRASS PHYLOG- ENY FROM rptl6 INTRON SEQUENCES 145DNA locus in North American duckwoods (Lemnaceae) 显示文摘Jordan W C Courtney W M Neigel E J 1996Am J Bot1996,83,:1
8Factors affecting the ultrasonic intermodulation crack detection technique using bispectral analysis显示文摘COURTNEY C R DRINKWATER B W NEILD S A 2008NDT&E International2008,41,3:1
9Purification and immunochemistry of a soluble matrix protein of the chicken eggshell显示文摘Hincke M T Tsang C P W Courtney M 1995Calcif Tissue Int1995,56,:1
10Resistance to ex- perimental infections with Fasciola hepatica in exotic and do-mestic breeds of sheep显示文摘Boyce W M Courtney C H Loggins P E 1987Parasitology International1987,17,7:1
11Bench scale testing of low-NOx LBG combustors 显示文摘CLARK W D FOLSOM B A SEEKER W R COURTNEY C W 1982Trans ASME: J Eng Power1982,104,:1
12Long-lived intestinal tuft cells serve as colon cancer-initiating cells显示文摘Westphalen C Benedikt Asfaha Samuel Hayakawa Yoku Takemoto Yoshihiro Lukin Dana J Nuber Andreas H Brandtner Anna Setlik Wanda Remotti Helen Muley Ashlesha Chen Xiaowei May Randal Houchen Courtney W Fox James G Gershon Michael D Quante Mich 2014Journal of Clinical Investigation2014,,3:1
13Surface heat treatment of En8 steel using a 2kW continuous -wave CO2 laser 显示文摘Steen W M Courtney C G H 1979Metals Technology1979,6,12:1
14Low levels of intraspecific genetic variation at a rapidly evolving chloroplast DNA locus in North American Duckweeds (Lemnaceae) 显示文摘Jordan W C Courtney M W Neigel J E 1996Amer J Bot1996,83,4:1
15A thoracic mechanism of mild traumat- ic brain injury due to blast pressure waves 显示文摘Courtney A C Courtney M W 2009Med Hypotheses2009,72,1:1
16Evaluation of isola- tion methods and RNA integrity for bacterial RNA quantitation 显示文摘COURTNEY E J AMY O C DAVID K W 2008Journal of Microbiological Methods2008,75,2:1
17显示文摘Baba P D Argentina G M Courtney W C 1972IEEE Trans Magn1972,8,:1
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