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| 1 | Spontaneous bacterial peritonitis prevalence in pretransplant patients and its effect on survival and graft loss post-transplant显示文摘AIM To investigate the incidence of spontaneous bacterial peritonitis(SBP) in pre-transplant patients and its effect on post transplant mortality and graft failure. METHODS We conducted a retrospective cohort study of patient records from the organ procurement and transplant network data set. Patients were identified by the presence of SBP pre-transplant. Univariate post-transplant survival models were constructed using the Kaplan-Meier technique and multivariate models were constructed using the Cox proportional hazards model. Variables that affected post-transplant graft survival were identified in the SBP population. RESULTS Forty-seven thousand eight hundred and eighty patient records were included in the analysis for both groups, and 1966(4.11%) patients were identified in the data set as having pre-transplant SBP. Patients that had pre-transplant SBP had higher rates of graft loss from recurrent hepatitis C virus(HCV)(3.6% vs 2.0%, P < 0.0001), infections leading to graft loss(1.9% vs 1.3%, P = 0.02), primary non-function(4.3% vs 3.0%, P < 0.0001) and chronic rejection(1.1% vs 0.7%, P = 0.04). Kaplan-Meier survival analysis showed a statistically significant difference in all-cause survival in patients with a history of SBP vs those without(P < 0.0001). Pretransplant history of SBP was independently predictiveof mortality due to recurrent HCV(HR = 1.11, 95%CI: 1.02-1.21, P < 0.017) after liver transplantation.CONCLUSION HCV patients prior to the advent of directing acting anti-viral agents had a higher incidence of pre-transplant SBP than other patients on the liver transplant wait list. SBP history pre-transplant resulted in a higher rate of graft loss due to recurrent HCV infection and chronic rejection. | Neeral L Shah Nicolas M Intagliata Zachary H Henry Curtis K Argo Patrick G Northup | 2016 | World Journal of Hepatology2016，8，36： | 2 |
| 2 | Advanced non-alcoholic steatohepatitis cirrhosis: A high-risk population for pre-liver transplant portal vein thrombosis显示文摘AIM To examine if liver transplant recipients with high-risk non-alcoholic steatohepatitis(NASH) are at increased risk for pre-transplant portal venous thrombosis.METHODS Data on all liver transplants in the United States from February 2002 through September 2014 were analyzed. Recipients were sorted into three distinct groups: High-risk(age > 60, body mass index > 30 kg/m2, hypertension and diabetes), low-risk and non-NASH cirrhosis. Multivariable logistic regression models were constructed.RESULTS Thirty-five thousand and seventy-two candidates underwent liver transplantation and of those organ recipients, 465 were transplanted for high-risk and 2775 for lowrisk NASH. Two thousand six hundred and twentysix(7.5%) recipients had pre-transplant portal vein thrombosis; 66(14.2%) of the high-risk NASH group had portal vein thrombosis vs 328(11.8%) of the lowrisk NASH group. In general, all NASH recipients were less likely to be male or African American and more likely to be obese. In adjusted multivariable regression analyses, high-risk recipients had the greatest risk ofpre-transplant portal vein thrombosis with OR = 2.11(95%CI: 1.60-2.76, P < 0.001) when referenced to the non-NASH group.CONCLUSION Liver transplant candidates with high-risk NASH are at the greatest risk for portal vein thrombosis development prior to transplantation. These candidates may benefit from interventions to decrease their likelihood of clot formation and resultant downstream hepatic decompensating events. Prospective study is needed. | Jonathan G Stine Curtis K Argo Shawn J Pelletier Daniel G Maluf Stephen H Caldwell Patrick G Northup | 2017 | World Journal of Hepatology2017，9，3： | 2 |
| 3 | Determination of Mariners' Reaction Times显示文摘 | | 1980 | Journal of Navigation1980，31，： | 1 |
| 4 | Inverse algorithm for tsunami forecasts显示文摘 | Wei Y Cheung K F Curtis G D | 2003 | J Waterw Port Coastal Ocean Eng2003，129，2： | 1 |
| 5 | A method for analyzing plant architecture as it relates to fruit qualibty using three-dimensional computer graphics显示文摘 | Smith G S Curtis J P Edwards C M | 1992 | Annals of Botany1992，70，： | 1 |
| 6 | Integration of biocontrol yeast and thiabendazole protects stored apples from fungicide sensitive and resistant isolates of Botrytis cinerea显示文摘 | LIMA G de CURTIS F PIEDIMONTE D | | 0，，03： | 1 |
| 7 | Feedback on Student Writing:Taking the Middle Path显示文摘 | Jacobs G&Curtis | 1998 | Journal of Second Language Writing1998，，3： | 1 |
| 8 | Determination of L-camitine, acetyl- L-camitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivalization with 1- aminoanthracene显示文摘 | Longo A Bruno G Curti S | 1996 | J Chromatogr B Biomed Appl1996，686，2： | 1 |
| 9 | Medical costs of ab- normal serum sodium levels显示文摘 | Shea A M Hammill B G Curtis L H | 2008 | J Am Soc Nephrol2008，19，4： | 1 |
| 10 | Inverse algorithm for tsunami forecasts显示文摘 | Wei Y Cheung K F Curtis G D | 2003 | Journal of waterway port coastal and ocean engineering2003，129，2： | 1 |
| 11 | A comparative study of germination characteristics in a local flora显示文摘 | Grime JP Mason G Curtis AV | 1981 | Journal of Ecology1981，69，： | 1 |
| 12 | Characterization of the Co2+ and NI2+ bind ing amino-acid residuces of the N-terminus of human albumin显示文摘 | Bar-or D Curtis G Rao N | 2001 | Eur J Biochem2001，268，1： | 1 |
| 13 | β-1,3-glucanase activity of two saprophytic yeasts and possible mode of action as biocontrol agents against postharvest diseases显示文摘 | CASTORIA R DE CURTIS F LIMA G | | 0，，： | 1 |
| 14 | Vapor phase butanal self-condensation over unsupported and supported alkaline earth metal oxides 显示文摘 | SHEN Wen-qin TOMPSETT G A XING Rong CURTIS CONNER W Jr HUBER G W | 2012 | Journal of Catalysis2012，286，： | 1 |
| 15 | Characteristic of the Co^2+ and Ni^2+ binding amino-acid residues of the N-terminus of human albumin an insight into mechanism of a new assay for myocardial ischemia显示文摘 | BAR-OR D CURTIS G RAO N | 2001 | Eur J Biochem2001，268，： | 1 |
| 16 | Dexmedetomidine and S(+)-ketamine in ischemia and reperfusion injury in the rat kidney 显示文摘 | CURTIS F G VIANNA P T VIERO R M | 2011 | Acta Cir Bras2011，26，3： | 1 |
| 17 | Extension of drought re cords for Central Asiausing tree rings: West-Central Mongolia显示文摘 | Davi N K G C Jaeoby A E Curtis | 2006 | J Climate2006，19，2： | 1 |
| 18 | A comparative study of germination characteristics in a local Flora显示文摘 | Grime J P Mason G Curtis A V | 1981 | Journal of Ecology1981，69，3： | 1 |
| 19 | Vereinfachtes Verfahren Zur Berechung von Tellerfedern显示文摘 | Curti G Orlando M Podda G | 1980 | Draht1980，31，11： | 1 |
| 20 | Characterization of the Co^2+ and Ni^2+ binding amino-acid residues of the N-terminus of human albumin 显示文摘 | Bar-Or D Curtis G Rao N | 2001 | Eur J Bioehem2001，268，1： | 1 |
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