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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Clinical applications of advanced magnetic resonance imaging techniques for arthritis evaluation显示文摘Magnetic resonance imaging(MRI) has allowed a comprehensive evaluation of articular disease, increasing the detection of early cartilage involvement, bone erosions, and edema in soft tissue and bone marrow compared to other imaging techniques. In the era of functional imaging, new advanced MRI sequences are being successfully applied for articular evaluation in cases of inflammatory, infectious, and degenerative arthropathies. Diffusion weighted imaging, new fat suppression techniques such as DIXON, dynamic contrast enhanced-MRI, and specific T2 mapping cartilage sequences allow a better understanding of the physiopathological processes that underlie these different arthropathies. They provide valuable quantitative information that aids in their differentiation and can be used as potential biomarkers of articular disease course and treatment response. | Teodoro Martín Noguerol Antonio Luna Marta Gómez Cabrera Alexie D Riofrio | 2017 | World Journal of Orthopedics2017，8，9： | 2 |
| 3 | Advances in the management of cholangiocarcinoma显示文摘Cholangiocarcinoma(CCA)is a primary malignancy of the bile ducts with three anatomically and molecularly distinct entities:Intrahepatic CCA(iCCA),perihilar CCA(pCCA),and distal CCA.As a result of phenotypic and anatomic differences they differ significantly with respect to management.For each type of CCA there have been significant changes in management over the last several years which will be discussed in this review.Although resection remains the standard of care for all types of CCA,liver transplantation has been established as curative treatment for selected patients with pCCA and is being evaluated for iCCA with early success.With respect to systemic therapy capecitabine is now first line adjuvant therapy for all biliary tract malignancies after curative intent resection.Progress in exploiting the pathologic mutations and molecular abnormalities has also yielded regulatory approval of targeted therapy for CCA in patients with acquired alterations in the fibroblast growth factor receptor.There is also increased consensus in managing malignant biliary obstruction associated with CCA where pre-operative biliary stenting is not beneficial while self-expanding metal stents have been shown to be superior to plastic stents in patients who are not surgical candidates. | Andreas G Zori Dennis Yang Peter V Draganov Roniel Cabrera | 2021 | World Journal of Hepatology2021，13，9： | 2 |
| 4 | Performance of a broad-band acoustic doppler current profiler显示文摘 | BRUMLEY CABRERA R G | 1991 | IEEE Journal of Oceanic Engineering1991，16，4： | 1 |
| 5 | Influence of heavy metals on growth and ferrous sulphate oxidation by Acidithiobacillus ferrooxidans in pure and mixed cultures 显示文摘 | CABRERA G G6MEZ J M CANTERO D | 2005 | Process Biochemistry2005，40，8： | 1 |
| 6 | Preparation of carbon molecular sieves,two step hydrocarbon decomposition with a single hydrocarbon显示文摘 | Cabrera A L Zehner J E Coe C G | | 0，，： | 1 |
| 7 | The role of biological y active peptides in tissue repair using umbilical cord mesenchymal stem cells显示文摘 | Cabrera C Carriquiry G Pierinel i C | | 0，，： | 1 |
| 8 | Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulumretention signal is N-glycosylated homogeneously throughout the plant with mostly high-mannose-type N-glycans 显示文摘 | Triguero A Cabrera G Cremata JA | 2005 | Plant Biotechnol J2005，3，4： | 1 |
| 9 | Tradescantia micronucleus biossay显示文摘 | Cabrera G L Chen R | 1994 | Mutat Res1994，310，： | 1 |
| 10 | Metal concentrations in scleractionean corals determined by instrumental neutron activation analysis and atomic absorption spectro-metry显示文摘 | Saunders M G Cabrera M E M Peraza E F H | 1997 | Journal of Radioanalytical and Nuclear Chemistry1997，219，： | 1 |
| 11 | Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulumretention signal is N-glycosylated homogeneously throughout the plant with mostly highmannose-type N-glycans显示文摘 | Triguero A Cabrera G Cremata J A | 2005 | Plant Biotechnology Journal2005，3，4： | 1 |
| 12 | Influence of growth temperature on cryotolerance and lipid composition of lactobacillus acidophilus显示文摘 | FERNANDEZ MURGA M L CABRERA G M FONT DE VALDEZ G | 2000 | Journal of Applied Microbiology2000，88，2： | 1 |
| 13 | Apoptosis as a possible mechanism of infertility in Echinococcus granulosus cyst 显示文摘 | Paredes R Jimenez V Cabrera G | 2007 | Cell Biochem2007，100，5： | 1 |
| 14 | Retention capacity of chitosan for copper and mercury ions 显示文摘 | Taboada E Cabrera G Cardenas G | 2003 | Journal of the Chilean Chemical Society2003，48，1： | 1 |
| 15 | Superantigens in- crease the survival of mice bearing T cell lymphomas by indu- cing apoptosis of neoplastic cells 显示文摘 | Mundifiano J Berguer PM Cabrera G et ol | 2010 | PLoS One2010，5，15： | 1 |
| 16 | Effect of air-oxygen and argon-oxygen mixtures on dielectric barrier dischargedecomposition of toluene显示文摘 | Cabrera O G Callejas R L Valencia R | 2004 | Brazilian Journal of Physics2004，34，4： | 1 |
| 17 | Deterioration of concrete due to reinforcement steel corrosion显示文摘 | CABRERA J G | 1996 | Cem & Concr Compos1996，18，1： | 1 |
| 18 | External ultrasonic lipoplasty:an effective method of fat removal and skin shrinkage显示文摘 | CABRERA R C | 2000 | Plast Reeonstr Surg2000，105，2： | 1 |
| 19 | Rol of pituitary tumour-transforming gene (PTI'G) in the pituitary adenomas 显示文摘 | Sanchez-Ortiga R Sanchez Tejada L Peiro Cabrera G | 2010 | Endocrinol Nutr2010，57，： | 1 |
| 20 | Anaphylaxis to omeprazole显示文摘 | Pedro A Galindo Jesús Borja Francisco Feo Elisa Gómez Rosa Garcia Martha Cabrera Consuelo Martinez | 1999 | Annals of Allergy, Asthma & Immunology1999，，： | 1 |
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