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| 1 | Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets显示文摘Background: Creep feeding is used to stimulate piglet post-weaning feed consumption.L-Glutamine(GLN) is an important source of fuel for intestinal epithelial cells.The objective of this study was to determine the impact of creep feeding and adding GLN or AminoGut(AG;containing glutamine + glutamate) to pre-and post-weaning diets on pig performance and intestinal health.Litters(N = 120) were allotted to four treatments during 14–21 d of lactation: 1) No creep feed(NC,n = 45);2) creep fed control diet(CFCD,n = 45);3) creep fed 1% GLN(CFGLN,n = 15);4) creep fed.88% AG(CFAG,n = 15).After weaning,the NC and CFCD groups were sub-divided into three groups(n = 15 each),receiving either a control nursery diet(NC-CD,CFCD-CD) or a diet supplemented with either GLN(NC-GLN,CFCD-GLN) or with AG(NC-AG,CFCD-AG).Litters that were creep fed with diets containing GLN or AG also were supplemented with those amino acids in the nursery diets(CFGLN-GLN,CFAG-AG).Glutamine was added at 1% in all three post-weaning diet phases and AG was added at.88% in phase 1 and 2 and at.66% in phase 3.Results: Feed conversion(feed/gain) showed means among treatment means close to significance(P = 0.056) and Tukey's test for pairwise mean comparisons showed that Pigs in the CFGLN-GLN group had the best feed conversion(feed/gain) in the first three-week period post-weaning,exceeding(P = 0.044) controls(CFCD-CD) by 34%.The NC-AG group had(P = 0.02) the greatest feed intake in the last three week of the study,exceeding controls(CFCD-CD) by 12%.CFGLN-GLN,CFCD-GLN and sow reared(SR) pigs had the greatest(P = 0.049) villi height exceeding the CFCD-AG group by 18%,20% and 19% respectively.The CFAG-AG group had the deepest(P = 0.001) crypts among all treatments.CFGLN-GLN,CFCD-GLN and SR groups had the greatest(P = 0.001) number of cells proliferating(PCNA) exceeding those in the NC-CD group by 43%,54% and 63% respectively.Sow reared pigs showed the greatest(P = 0.001) intestinal absorption capacity for xylose and mannitol.Conclusion: Supplementation of creep feed and nursery diets with GLN and/or AminoGut in the first three week improved feed conversion possibly due to improved intestinal health. | Rafael A Cabrera James L Usry Consuelo Arrellano Eduardo T Nogueira Marianne Kutschenko Adam J Moeser Jack Odle | 2013 | Journal of Animal Science and Biotechnology2013，4，3： | 17 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Hot ductility behavior of boron microalloyed steels显示文摘 | E. López-Chipres I. Mejía C. Maldonado A. Bedolla-Jacuinde J.M. Cabrera | 2007 | Materials Science & Engineering A2007，，： | 2 |
| 4 | Principles of assessment and effective feedback显示文摘The highly competitive offer of medical training programs and schools,globalization and constant mobility of physicians and medical students(MS),and the commitment to society to deliver competent physicians,demands the definition of performance standards.This would allow to make their performances comparable no matter where they studied or which textbook did they used as reference,to have evaluation mechanisms that guarantee mastery of the integral evaluation of the performance.Assessment has been the key in the teaching-learning process as this obtains a formative and summative element,at different moments,from the extent to which the students have acquired knowledge,skills and attitudes.The progress of the learner must be enhanced with effective feedback on their performance and self-direction of the results obtained in each of the mechanisms established.If,traditionally,this has been considered as the accreditation of compliance with a standard,the evaluation also functions in an integral way as a formative process that identifies advances and deficiencies in the training of residents that allows the definition of actions and strategies for improving the operation of the programs.Different assessment mechanisms are associated with the areas of competence domain,some of the most common tools are:theoretical exams,checklists and rubrics,portfolio,projects and challenges.However,the importance of defining standards which are perceived as fair and designed according to the learning objectives remains a priority to guarantee the credibility of the evaluation agencies and institutions.Some strategies to assure credibility include the involvement of expert and trained evaluators,allowing the process to be carried out with transparency and diligence,and the principles employed should be supported by educational research. | Jorge Eugenio Valdez-García Mildred Vanessa López Cabrera Elena Ríos Barrientos | 2017 | Annals of Eye Science2017，，1： | 2 |
| 5 | Modulation of matrix metalloproteinase-9 activity by hyaluronan is dependent on NF-kappaB activity in lymphoma cell lines with dissimilar invasive behavior显示文摘 | Alaniz L Garcia M Cabrera P | 2004 | Biochem Biophys Res Commun2004，324，2： | 1 |
| 6 | Effects of drying and rewetting on carbon and nitrogen mineralization in soils and incorporated residues显示文摘 | Kruse J S Kissel D E Cabrera M L | 2004 | Nutr Cycl Agroeco- sys2004，69，： | 1 |
| 7 | Influence of biochar amendments on the sorption-desorption of aminocyclopyrachlor, bentazone and pyraclostrobin pesticides to an agricultural soil显示文摘 | Cabrera A Cox L Spokas K | 2014 | Science of the Total Environment2014，，： | 1 |
| 8 | Tuning the stator resistance of induction motors using the artificial neural network 显示文摘 | Cabrera L A Elbuluk M E Husain I | 1997 | IEEE Trans on PE1997，12，5： | 1 |
| 9 | The essential oil of Senecio graveolens(Compositae) : Chemical composition and antimicrobial activity tests 显示文摘 | PEREZ C AGNESE A M CABRERA J L | 1999 | Journal of Ethnopharmacology1999，66，2： | 1 |
| 10 | Improved blastocyst development with microfluidics and braille pin actuator enabled dynamic culture显示文摘 | Cabrera L Heo Y Ding J | 2006 | Fertil Steril2006，87，3： | 1 |
| 11 | Ammonia volatilization from urea, ammonium sulfate and NutraSweet sludge in bare and straw-cov- ered soils显示文摘 | Shahandeh H Cabrera M L Sumner M E | 1992 | Communications in Soil Science and Plant A nolysis1992，23，78： | 1 |
| 12 | Aggregate-protected and unprotected organic matter pools in conventional and no-tillage soils 显示文摘 | BEARE M H HENDRIX P F CABRERA M L | 1994 | Soil Science Society of America Journal1994，58，3： | 1 |
| 13 | Intensity of inflammation, density of colonization and interlerkin - 8 response in gastric mueosa of children infected with Helieohacter pylori显示文摘 | Canorlinga PM Aviles JF Cabrera L | 2003 | Helicobacter2003，8，5： | 1 |
| 14 | Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle 显示文摘 | JI L L GOMEZ CABRERA M C STEINHAFEL N | 2004 | FASEB J2004，18，13： | 1 |
| 15 | Learning technique to train neural networks as a state selector for inverter-fed induction machines using direct torque control 显示文摘 | Cabrera L A Elbuluk M E Zinger D S | 1997 | IEEE Trans on PE1997，12，5： | 1 |
| 16 | Aggregate-protected and unprotected organic matter pools in conventional-tillage and no-tillage soils显示文摘 | Beate M H Cabrera M L Hendrix P F | 1994 | Soil Sci Soc Am J1994，58，： | 1 |
| 17 | Parallel activationof mitochondrial oxidative metabolism with increasedcardiac energy expenditure is not dependent on fatty acidoxidation in pigs显示文摘 | Zhou L Cabrera ME Huang H | 2007 | J Physiol2007，579，3： | 1 |
| 18 | Preparation of carbon molecular sieves,two step hydrocarbon decomposition with a single hydrocarbon显示文摘 | Cabrera A L Zehner J E Coe C G | | 0，，： | 1 |
| 19 | Film pressure distribution in water-lubricated rubber journal bearings显示文摘 | Cabrera D L Woolley N H | 2005 | Journal of Engineering Tribology2005，219，2： | 1 |
| 20 | Performance of a broad-band acoustic doppler current profiler显示文摘 | BLAIR H BR UMLEY R AMONG CABRERA KENT L DEINES | 1991 | Journal of Oceanic Engineering1991，16，4： | 1 |
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