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| 1 | Epididymis-specific lipocalin promoters显示文摘我们的目标是译解序列它 DNA 为附睾基因的 tissue-specificexpression 被要求。至少 6 epididymis 特定的 lipocalin 基因被知道。这些不同地在附睾被调整并且区域化。Lipocalin 5 (Lcn5 或 mE-RABP ) andLipocalin (Lcn8 或 mEP17 ) 8 是属于 epididymis 特定的 lipocalin 基因簇的相应基因。两个都, Lcn5 基因和 5.3 kb 倡导者的 5 kb 倡导者碎片直接 theLcn8 基因罐头碎裂在附睾(到远侧的头的 Lcn5 和到起始的片断的 Lcn8 ) 的 transgene 表示,显示这些倡导者碎片为 epididymis 特定的基因表示包含重要 cis-regulatoryelement。为了定义,推进调整基因表示的碎片, Lcn5 倡导者在转基因的鼠标被检查并且使附睾房间线不朽。在连续删除以后, Lcn5 基因的 1.8 kb 倡导者碎片是在转基因的老鼠的足够的 fortissue 特定、区域特定的基因表示。短暂 transfectionanalysis 表明抄写因素叉头框 A2 ( Foxa2 )与雄激素受体交往并且绑在 Lcn5 倡导者 activity.Immunohistochemistry 感应的雄激素依赖者显示了的 kb 和 1.3 kb 和 thatFoxa2 表示禁止的在 1.2 之间的 Lcn5 倡导者的 100 bp 碎片在附睾的 Foxa2 的一个限制表达式在哪儿 endogenousLcn5 基因表示被压制并且 Lcn5 倡导者的 Foxa2 抑制与在语料库和尾的 Lcn5 的表示的缺乏一致。我们的途径为附睾 lipocalin 基因规定的进一步的分析和 epididymalfunction 的灵活控制提供基本策略。 | Kichiya Suzuki Xiuping Yu Pierre Chaurand Yoshihiko Araki Jean-Jacques Lareyre Richard M. Caprioli Marie-Claire Orgebin-Crist Robert J. Matusik | 2007 | Asian Journal of Andrology2007，9，4： | 3 |
| 2 | Neuroprotection of the optic nerve in glaucoma 显示文摘 | Caprioli J | 1997 | Acta Ophthalmol Scand1997，75，： | 2 |
| 3 | The spontaneously hypertensiverat as an animal model of ADHD:evidence for impulsive and non-impulsive subpopulations显示文摘 | Adriani W Caprioli A Granstrem O | 2003 | Neurosci Biobehav Rev2003，27，7： | 1 |
| 4 | Polymorphisms of EDNRB, ATG,and ACE genes in salt - sensitive hypertension显示文摘 | Caprioli J Mele C Mossali C | 2008 | Can J Physiol Pharmacol2008，86，8： | 1 |
| 5 | Circulating ghrelin levels in patients with inflammatory bowel disease 显示文摘 | Peracchi M Bardella MT Caprioli F | 2006 | Gut2006，55，3： | 1 |
| 6 | Hyperthermia and hypoxia increase tolerance of retinal ganglion cells to anoxia and excitotoxicity显示文摘 | CAPRIOLI J KITANO S MORGAN J E | 1996 | Invest Ophthalmol Vis Sci1996，37，12： | 1 |
| 7 | High-Performance Throughput Computing显示文摘 | Chaudhry S Caprioli P Yip S | 2005 | IEEE Micro2005，25，3： | 1 |
| 8 | Detection of vacuolating toxin of Helicobacter pylori in human faeces显示文摘 | Luzzi I Pezzella C Caprioli A | 1993 | Lancet1993，341，8856： | 1 |
| 9 | Effect of repeated administrations of heroin, naltrexone, methadone, and alcohol on morphine glucuronidation in the rat 显示文摘 | Antonilli L Petecchia E Caprioli D | 2005 | Psychopharmacology2005，182，1： | 1 |
| 10 | Hyperthermia and hypoxia increase tolerance of retinal ganglion cells to anoxia and excitotoxicity显示文摘 | Caprioli J Kitano S Morgan JE | 1996 | Invest Ophthalmol Vis Sci1996，37，12： | 1 |
| 11 | Nitric oxide mediates excitotoxic and anoxic damage in rat retinal ganglion cells cocultured with astroglia显示文摘 | Morgan J Caprioli J Koseki Y | 1999 | Arch Ophthalmol1999，117，11： | 1 |
| 12 | Rail inspection in track maintenance: a benchmark between the wavelet approach and more conventional Fourier analysis 显示文摘 | Caprioli A Cigada A Raveglia D | 2007 | Machanical Systems and Signal Processing2007，21，2： | 1 |
| 13 | Optimized deghosting of over/under towed-streamer data in the presence of noise显示文摘 | (O)zdemi A K Caprioli P Ozbek A | | 0，，02： | 1 |
| 14 | Enterohaemorrhagic Escherichia coli:emerging issue on virulence and modes of transmission显示文摘 | Caprioli A Morabito S Brugere H Oswald E | | 0，，： | 1 |
| 15 | Blood pressure, perfusion pressure, and glaucoma显示文摘 | CAPRIOLI J COLEMAN A L | 2010 | American Journal of Ophthalmo- logy2010，149，5： | 1 |
| 16 | Enterohaemorrhagic Escherichia coli:emerging issues on virulence and modes of transmission显示文摘 | | 2005 | Vet Res2005，36，3： | 1 |
| 17 | Long period study of outdoor radon concentration in Milan and Correlation between its temporal variations and dispersion properties of atmosphere显示文摘 | Sesana L Caprioli E Marcazzan G | | 0，，02： | 1 |
| 18 | Perspective: a program to improve protein biomarker discovery for cancer显示文摘 | Aebersold R Anderson L Caprioli R | 2005 | J Proteome Res2005，4，4： | 1 |
| 19 | Genetics of HUS : The impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome 显示文摘 | Caprioli J Noris M Brioschi S | 2006 | Blood2006，108，4： | 1 |
| 20 | Retinal ganglion cell death in experimental glaucoma显示文摘 | Mogran JE Uchidac H Caprioli J | 2000 | Br J Ophthalmol2000，84，3： | 1 |
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