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| 1 | Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model显示文摘骨头骨折愈合的起始的煽动性的阶段为愈合的过程的结果代表关键步。然而,开始这个煽动性的阶段的机制和在破裂地点在场的有免疫力的房间的功能糟糕被理解。以便在破裂 hematoma 以内学习早事件,我们建立了一在里面 vitro 破裂 hematoma 模型:我们有教养的 hematomas 在 bioenergetically 控制的条件下面在 vitro 在全部的新潮的关节造形术(THA ) 期间在腿节的截骨术(人工的骨头破裂) 期间形成。这个模型允许我们在跟随破裂的早阶段期间监视有免疫力的房间人口,房间幸存和 cytokine 表示。而且,这个模型使我们能改变 bioenergetical 条件以便模仿在里面 vivo 状况,它被假定被组织缺氧描绘并且限制了营养素的数量。用这个模型,我们发现有免疫力的房间经由 angiogenic 因素, chemoattractants 和支持 inflammatory 分子的表示适应组织缺氧。另外,联合了氧的限制,滋养的供应与 myeloid 的比较提高了淋巴细胞的选择幸存导出的房间(即, neutrophils ) 。笔记,非限制的 bioenergetical 条件没关于 cytokine 表示或有免疫力的房间子集的不同幸存率显示出任何类似的效果。在结论,我们发现 bioenergetical 条件在导致骨折愈合的起始的煽动性的阶段的关键因素之中并且因此是为在早破裂 hematoma 影响有免疫力的房间的幸存和功能的一个关键步骤。 | Paula Hoff Patrick Maschmeyer Timo Gaber Tabea Schiitze Tobias Raue Katharina Schmidt-Bleek Rene Dziurla Saskia Schellmann Ferenz Leonard Lohanatha Eric Rohner Andrea Ode Gerd-Riidiger Burmester Georg N Duda Carsten Perka Frank Buttgereit | 2013 | Cellular & Molecular Immunology2013，10，2： | 3 |
| 2 | Treatment of stages 2 and 3 giant-cell tumor显示文摘 | K. Labs Carsten Perka Richard G. Schmidt | 2001 | Archives of Orthopaedic and Trauma Surgery (-)2001，，1： | 1 |
| 3 | The Surgical Treatment of the Lumbar Disc Prolapse: Nucleotomy With Additional Transpedicular Dynamic Stabilization Versus Nucleotomy Alone显示文摘 | Michael Putzier Sascha V. Schneider Julia F. Funk Stephan W. Tohtz Carsten Perka | 2005 | Spine2005，，5： | 1 |
| 4 | Treatment of stages 2 and 3 giant-cell tumor显示文摘 | K. Labs Carsten Perka Richard G. Schmidt | 2001 | Archives of Orthopaedic and Trauma Surgery (-)2001，，1： | 1 |
| 5 | Epidemiology and injury patterns of aerial sports in Switzerland显示文摘BACKGROUND Airborne sports have become more popular in recent years.The number of accidents has increased linearly as athletes take increasingly greater risks to experience the adventurous spirit of this kind of sports.AIM To investigate the variety of injuries in airborne sport accidents,as well as which acute treatment these patients receive,both before and after admission to a levelone-trauma center.METHODS We performed a retrospective chart analysis at a major level-one-trauma center in Switzerland for 235-patients who were admitted following airborne sports injuries between 2010 and 2017.Patients’demographic data,injury patterns,emergency primary care procedures and intra-hospital care were recorded.RESULTS Overall,718-injuries in 235-patients were identified;the spine was the most commonly affected region with 46.5%of injuries(n=334/718)in 143-patients.In 69-patients(15.5%),the(non-spine)thorax was affected,followed by the lower and upper extremity,pelvis,head/face and abdominal injuries.Eleven-patients had to be intubated at the trauma site.Three patients were resuscitated after onset of pulseless-electrical-activity.Two-patients died in the resuscitation room.In 116-cases,surgery was indicated including 55-emergency surgeries.Another 19 patients(8.1%)were transferred to the intensive care unit.CONCLUSION Paragliders are most commonly affected,although the highest injury severities were identified for Building,Antenna,Span and Earth-jumping athletes.First responders,treating physicians and pilots should be aware of the risk for potentially serious and life-threatening injury with an in-hospital mortality of 0.9%. | Henrik Constantin Bäcker J Turner Vosseller Aristomenis K Exadaktylos Carsten Perka Lorin Michael Benneker Fabian Götz Krause Moritz Caspar Deml | 2020 | World Journal of Orthopedics2020，11，2： | 0 |
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