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| 1 | Fatty liver,carotid disease and gallstones:A study of age-related associations显示文摘AIM: To evaluate carotid intima-media thickening (IMT) and plaques, gallstone disease (GD) and fatty liver (FL) as a function of age. METHODS: In 449 subjects, FL and carotid disease were assessed ultrasonographically. In a subgroup of 65/449 patients with non-alcoholic fatty liver disease (NAFLD), carotid disease, GD and associated factors were determined. RESULTS: FL of unspecified etiology was more common in younger and GD in older individuals. FL subjects had an increased prevalence of IMT and a decreased prevalence of plaques and manifested carotid disease earlier. Plaques were more common in subjects with GD. Age was an independent predictor of carotid disease outcome and FL was a protective factor for plaques. In NAFLD, there was an inverse correlation between body weight and age and the latter independently predicted carotid findings. CONCLUSION: Cardiovascular risk in patients with FL and NAFLD needs to be assessed as a function of age and body weight. | Amedeo Lonardo Silvia Lombardini Federica Scaglioni Stefano Ballestri Anna Maria Verrone Marco Bertolotti Lucia Carulli Dorval Ganazzi Nicola Carulli Paola Loria | 2006 | World Journal of Gastroenterology2006，12，36： | 14 |
| 2 | Telomere and telomerase in chronic liver disease and hepatocarcinoma显示文摘The pathogenesis of liver cirrhosis is not completely elucidated.Although in the majority of patients,the risk factors may be identified in B and C viral hepatitis,alcohol intake,drugs or fatty liver disease,there is a small percentage of patients with no apparent risk factors.In addition,the evolution of chronic liver disease is highly heterogeneous from one patient to another.Among patient with identical risk factors,some rapidly progress to cirrhosis and hepatocellular carcinoma(HCC)whereas others have a benign course.Therefore,a genetic predisposition may contribute to the development of cirrhosis and HCC.Evidence supporting the role of genetic factors as a risk for cirrhosis has been accumulating during the past years.In addition to the results from epidemiological studies,polymorphisms studies and data on twins,the concept of telomere shortening as a genetic risk factor for chronic liver disease and HCC has been proposed.Here we review the literature on telomerase mutations,telomere shortening and liver disease including hepatocellular carcinoma. | Lucia Carulli Claudia Anzivino | 2014 | World Journal of Gastroenterology2014，20，20： | 12 |
| 3 | Telomere shortening as genetic risk factor of liver cirrhosis显示文摘Cirrhosis is the main complication of chronic liver disease, leads to progressive liver function impairment and is the main risk factor for the development of liver cancer. Liver failure at endstage cirrhosis is associated with increased mortality with liver transplantation as the only possible treatment at this stage. The pathogenesis of liver cirrhosis is not completely elucidated. Although the common factors leading to liver injury, such as viral hepatitis, alcohol consume or fatty liver disease can be identified in the majority of patients a small percentage of patients have no apparent risk factors. Moreover given the same risk factors, some patients progress to cirrhosis whereas others have a benign course, the reason remains unclear. In order to developnew diagnostic and therapeutic tools, it is s essential to understand the pathogenesis of cirrhosis. The identification of genetic risk factors associated with cirrhosis is one of the possible approach to achieve these goal. In the past years several studies have supported the role of telomere shortening and cirrhosis. In the recent year several studies on the relation between several single nucleotide polymorphism(SNPs) and cirrhosis have been published; it has been proposed also a cirrhosis risk score based on seven SNPs. Also epidemiological studies on identical twins and in different ethnic groups have been supporting the importance of the role of genetic risk factors. Finally in the very recent years it has been suggested that telomere shortening may represent a genetic risk factor for the development of cirrhosis. | Lucia Carulli | 2015 | World Journal of Gastroenterology2015，21，2： | 5 |
| 4 | Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD显示文摘 | Stefano Ballestri Amedeo Lonardo Dante Romagnoli Lucia Carulli Luisa Losi Christopher P. Day Paola Loria | 2012 | Liver Int2012，，8： | 4 |
| 5 | Should nonalcoholic fatty liver disease be renamed?显示文摘 | Loria P Lonardo A Carulli N | 2005 | Dig Dis2005，23，： | 1 |
| 6 | Simultaneous presenta- tion of Waldenstr6m macroglobulinemia and multiple myeloma: multidisciplinary diagnosis, treatment and 30-month follow-up 显示文摘 | Carulli G Ciancia EM Azzarh A | 2013 | J Clin Exp Hematop2013，53，1： | 1 |
| 7 | Classical and innovative insulin sensitizing drugs for the prevention and treatment of NAFLD显示文摘 | Carulli L Maurantonio M Hebbard L | | 0，，： | 1 |
| 8 | Reparative mechanisms in the cerebellar cortex显示文摘 | Carulli D Buffo A Strata P | | 0，，06： | 1 |
| 9 | MALDI- TOF MS characterization of glycation products of whey proteins in a glucose/galactose model system and lactose-free milk显示文摘 | Carulli S Calvano CD Palmisano F | 2011 | Journal of Agricuhural & Food Chemistry2011，59，5： | 1 |
| 10 | Inhibitory effects of human neutrophil functions by the 45 kDa glycoprotein derived from the parasitic nematode Trichinella spiralis显示文摘 | Bruschi F Carulli G Azzara A | 2000 | Int Arch Allergy Immunol2000，122，： | 1 |
| 11 | Relati,e contribution of iron bur- den, HFE mutations, and insulin resistance to fibrosis in nonalco- holic fatty liver 显示文摘 | Loria P Lonardo A Carulli N | 2004 | Hepatology2004，39，6： | 1 |
| 12 | The use of anti-osteoporosis drugs in total knee arthroplasty显示文摘 | Carulli C Civinini R Matassi F | 2011 | Aging Clin Exp Res2011，23，2： | 1 |
| 13 | Locking plate and fibular allograft augmentation in unstable fractures of proximal humerus显示文摘 | Matassi F Angeloni R Carulli C | 2012 | Injury2012，43，11： | 1 |
| 14 | Bone marrow infiltration in B-cell non-Hodgkin's lymphomas:comparison between flow cytometry and bone marrow biopsy显示文摘 | Carulli G Canigiani S Volpini M | | 0，，06： | 1 |
| 15 | Animals lacking link protein have attenuated perineuronal nets and persistent plasticity 显示文摘 | Carulli D Pizzorusso T Kwok J C | 2010 | Brain2010，133，8： | 1 |
| 16 | Reparativemechanisms in the cerebellar cortex 显示文摘 | Carulli D Buffo A Strata P | 2004 | Prog Neurobio2004，72，6： | 1 |
| 17 | Reparative mechanisms in the cerebellar cortex显示文摘 | Carulli D Buff A Strata P | 2004 | Prog Neurobiol2004，72，6： | 1 |
| 18 | Vitamin D3 administration and multidrug resistance in acute nonlym- phoblastic leukemia 显示文摘 | Petrini M Caracciolo F Carulli G | 1993 | Acta Haematol-Basel1993，89，4： | 1 |
| 19 | Bilateral primary renallymphoma treated by surgery and chemotherapy 显示文摘 | Cupisti A Riccioni R Carulli G | 2004 | Nephrol DialTransp2004，19，6： | 1 |
| 20 | A dual-mobility cup reduces risk of dislocation in isolated acetab*ular revisions显示文摘 | Roberto Civinini MDtChristian Carulli MD(Fabrizio Matassi MD etai | 2012 | Clin Orthop Relat Res2012，470，12： | 1 |
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