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| 1 | Relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is the most common chronic liver disease worldwide.Its pathogenesis is complex and not yet fully understood.Over the years many studies have proposed various pathophysiological hypotheses,among which the currently most widely accepted is the'multiple parallel hits'theory.According to this model,lipid accumulation in the hepatocytes and insulin resistance increase the vulnerability of the liver to many factors that act in a coordinated and cooperative manner to promote hepatic injury,inflammation and fibrosis.Among these factors,adipose tissue dysfunction and subsequent chronic low grade inflammation play a crucial role.Recent studies have shown that vitamin D exerts an immune-regulating action on adipose tissue,and the growing wealth of epidemiological data is demonstrating that hypovitaminosis D is associated with both obesity and NAFLD.Furthermore,given the strong association between these conditions,current findings suggest that vitamin D may be involved in the relationship between adipose tissue dysfunction and NAFLD.The purpose of this review is to provide an overview of recent advances in the pathogenesis of NAFLD in relation to adipose tissue dysfunction,and in the pathophysiology linking vitamin D deficiency with NAFLD and adiposity,together with an overview of the evidence available on the clinical utility of vitamin D supplementation in cases of NAFLD. | Flavia A Cimini Ilaria Barchetta Simone Carotti Laura Bertoccini Marco G Baroni Umberto Vespasiani-Gentilucci Maria-Gisella Cavallo Sergio Morini | 2017 | World Journal of Gastroenterology2017，23，19： | 9 |
| 2 | Polyomavirus-associated nephropathy显示文摘Polyomaviruses BK and JC are ubiquitous viruses with high seroprevalence rates in general population.Following primary infection,polyomaviruses BK and JC persist latently in different sites,particularly in the reno-urinary tract.Reactivation from latency may occur in normal subjects with asymptomatic viruria,while it can be associated to nephropathy(PVAN)in kidney transplantat recipients.PVAN may occur in 1%-10%of renal transplant patients with loss of the transplanted organ in 30%up to 80%of the cases.Etiology of PVAN is mainly attributable to BK virus,although approximately5%of the cases may be due to JC.Pathogenesis of PVAN is still unknown,although viral replication and the lack of immune control play a major role.Immunosuppression represents the condicio sine qua non for the development of PVAN and the modulation of anti-rejection treatment represents the first line of intervention,given the lack of specific antiviral agents.At moment,an appropriate immunemodulation can only be accomplished by early identification of viral reactivacation by evaluation of polyomavirus load on serum and/or urine specimens,particularly in the first year post-trasplantation.Viro-immunological monitoring of specific cellular immune response could be useful to identify patients unable to recover cellular immunity posttransplantation,that are at higher risk of viral reactivation with development of PVAN.Herein,the main features of polyomaviruses BK and JC,biological properties,clinical characteristics,etiopathogenesis,monitoring and diag-nosing of PVAN will be described and discussed,with an extended citation of related relevant literature data. | Cristina Costa Rossana Cavallo | 2012 | World Journal of Transplantation2012，2，6： | 6 |
| 3 | Overview of studies of the vitamin D/vitamin D receptor system in the development of non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is the most common chronic liver disease in the world.NAFLD is known to be associated with obesity,type 2 diabetes,metabolic syndrome and increased cardiovascular events:for these reasons,it is becoming a global public health problem and represents an important challenge in terms of prevention and treatment.The mechanisms behind the pathogenesis of NAFLD are multiple and have not yet been completely unraveled;consequently,at moment there are not effective treatments.In the past few years a large body of evidence has been assembled that attributes an important role in hepatic aberrant fat accumulation,inflammation and fibrosis,to the vitamin D/vitamin D receptor(VD/VDR)axis,showing a strong association between hypovitaminosis D and the diagnosis of NAFLD.However,the data currently available,including clinical trials with VD supplementation,still provides a contrasting picture.The purpose of this editorial is to provide an overview of recent advances in the pathogenesis of NAFLD in relation to VD/VDR.Based on recent data from literature,we focused in particular on the hypothesis that VDR itself,independently from its traditional ligand VD,may have a crucial function in promoting hepatic fat accumulation.This might also offer new possibilities for future innovative therapeutic approaches in the management of NAFLD. | Flavia Agata Cimini Ilaria Barchetta Simone Carotti Sergio Morini Maria Gisella Cavallo | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，2： | 4 |
| 4 | Emotion Modelling for Social Robotics Applications: A Review显示文摘 | Filippo Cavallo Francesco Semeraro Laura Fiorini Gergely Magyar Peter Sincadk Paolo Dario | 2018 | Journal of Bionic Engineering2018，15，2： | 4 |
| 5 | Photophysics and electrochemistry relevant to photocatalytic water splitting involved at solid–electrolyte interfaces显示文摘Direct photon to chemical energy conversion using semiconductor–electrocatalyst–electrolyte interfaces has been extensively investigated for more than a half century. Many studies have focused on screening materials for efficient photocatalysis. Photocatalytic efficiency has been improved during this period but is not sufficient for industrial commercialization. Detailed elucidation on the photocatalytic water splitting process leads to consecutive six reaction steps with the fundamental parameters involved: The photocatalysis is initiated involving photophysics derived from various semiconductor properties(1: photon absorption, 2: exciton separation). The generated charge carriers need to be transferred to surfaces effectively utilizing the interfaces(3: carrier diffusion, 4: carrier transport). Consequently, electrocatalysis finishes the process by producing products on the surface(5: catalytic efficiency, 6: mass transfer of reactants and products). Successful photocatalytic water splitting requires the enhancement of efficiency at each stage. Most critically, a fundamental understanding of the interfacial phenomena is highly desired for establishing 'photocatalysis by design' concepts, where the kinetic bottleneck within a process is identified by further improving the specific properties of photocatalytic materials as opposed to blind material screening. Theoretical modeling using the identified quantitative parameters can effectively predict the theoretically attainable photon-conversion yields. This article provides an overview of the state-of-the-art theoretical understanding of interfacial problems mainly developed in our laboratory.Photocatalytic water splitting(especially hydrogen evolution on metal surfaces) was selected as a topic,and the photophysical and electrochemical processes that occur at semiconductor–metal, semiconductor–electrolyte and metal–electrolyte interfaces are discussed. | Tatsuya Shinagawa Zhen Cao Luigi Cavallo Kazuhiro Takanabe | 2017 | Journal of Energy Chemistry2017，26，2： | 3 |
| 6 | Venous Lower-Limb Evaluation in Patients With Acute Pulmonary Embolism显示文摘 | Fulvio Pomero Chiara Brignone Cristina Serraino Sergio Panzone Christian Bracco Elena Migliore Paola Dalmasso Paolo Cavallo Perin Luigi Maria Fenoglio | 2011 | Southern Medical Journal2011，，6： | 2 |
| 7 | Cortisol and immune interferon can interact in the modulation of human natural killer cell activity显示文摘 | R. Cavallo M. L. Sartori G. Gatti A. Angeli | 1986 | Experientia1986，，2： | 2 |
| 8 | 全无机卤素钙钛矿中的量子限域效应(英文)显示文摘当半导体材料尺寸缩小到与激子尺寸相当时,量子限域效应会在对应的低维材料中诱导出不同的物理行为.本文以CsPbBr_3为例,报道了在全无机钙钛矿纳米片中的量子限域效应.根据DFT理论模拟可知,当CsPbBr_3材料减薄至7纳米左右时,该效应导致该材料的光吸收和光致发光光谱的峰位蓝移,且样品越薄,峰位蓝移现象越明显.该效应也会导致激子束缚能随着材料厚度的减薄而显著增大.同时,变温光致发光光谱的光强-温度与半高宽-温度函数都显示出厚度越薄量子限域效应越强的趋势.本文揭示了二维全无机卤化物钙钛矿的量子限域效应,可为设计全无机卤化物钙钛矿光电器件提供参考依据. | 蔡波 李晓明 顾宇 Moussab Harb 李建海 谢美秋 曹菲 宋继中 张胜利 Luigi Cavallo 曾海波 | 2017 | Science China Materials2017，60，9： | 2 |
| 9 | MR-Guided High-Intensity Focused Ultrasound: Current Status of an Emerging Technology显示文摘 | Alessandro Napoli Michele Anzidei Federica Ciolina Eugenio Marotta Beatrice Cavallo Marincola Giulia Brachetti Luisa Mare Gaia Cartocci Fabrizio Boni Vincenzo Noce Luca Bertaccini Carlo Catalano | 2013 | CardioVascular and Interventional Radiology2013，，5： | 2 |
| 10 | Sellar repair in endoscopic endonasal transsphenoidal surgery: results of 170cases 显示文摘 | Cavallo LM Esposito F | 2002 | Neurosurgery2002，51，6： | 1 |
| 11 | Thymoma:results of 241 operated cases 显示文摘 | Maggi G Casdio C Cavallo A | 1990 | Ann Thorac Surg1990，51，： | 1 |
| 12 | Report of the third Banff conference on allograft pathology on classification and lesion scoring in renal allograft pathogy显示文摘 | Solez K Benediktsson H Cavallo T | 1996 | Transplant Proc1996，28，： | 1 |
| 13 | Antibodies to bovine beta- casein in diabetes and other autoimmune diseases 显示文摘 | Monetini L Cavallo MG Manfrini S | 2002 | Horm Metab Res2002，34，： | 1 |
| 14 | Very delayed hy- ponatremia after surgery and radiotherapy for pituitary macroade- noma 显示文摘 | Fillipella M Cappabianca P Cavallo LM | 2002 | J Endocrinol Invest2002，25，2： | 1 |
| 15 | 显示文摘 | M. Trento P. Passera M. Bajardi M. Tomalino G. Grassi E. Borgo C. Donnola F. Cavallo P. Bondonio M. Porta | 2002 | Diabetologia2002，，9： | 1 |
| 16 | Diagnostic performance of 64-MDCT and 1.5-T MRI with highresolution sequences in the T staging of gastric cancer: a comparative analysis with histopathology显示文摘 | M. Anzidei A. Napoli F. Zaccagna P. Paolo C. Zini B. Cavallo Marincola D. Geiger C. Catalano R. Passariello | 2009 | La radiologia medica2009，，7： | 1 |
| 17 | A sliding manifold approach for vibration reduction of flexible systems显示文摘 | Cavallo A de Maria G Setola R | 1999 | Automatica1999，35，10： | 1 |
| 18 | Conformation of tri-and tetra-substituted 2-fluorocyclohexanones:proton non-equivalence F-H and F-C coupling constants,conformational dependence of ^3JFH and ^4JFH显示文摘 | Solladié-Cavallo A Jierry L Bouérat L | 2002 | Tetrahedron2002，58，： | 1 |
| 19 | Safty and ef-ficacy of iron sucrose in patients sensitire to iron dextan; North Amoerican clinical trial 显示文摘 | Van Wyck DB Cavallo G spinwitz BS | 2000 | Am J Kidney Dis2000，36，1： | 1 |
| 20 | Easy sellar reconstruction in endoscopic endonasal transsphenoidal surgery with polyester-silicone dural substitute and fibrin glue:technical note 显示文摘 | Cavallo LM Mariniello G | 2001 | Neurosurgery2001，49，2： | 1 |
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