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| 1 | Advanced gastric cancer:what we know and what we stillhave to learn显示文摘Gastric cancer is a common neoplastic disease and, more precisely, is the third leading cause of cancer death in the world, with differences amongst geographic areas. The definition of advanced gastric cancer is still debated. Different stadiating systems lead to slightly different stadiation of the disease, thus leading to variations between the single countries in the treatment and outcomes. In the present review all the possibilities of treatment for advanced gastric cancer have been analyzed. Surgery, the cornerstone of treatment for advanced gastric cancer, is analyzed first, followed by an investigation of the different forms and drugs of chemotherapy and radiotherapy. New frontiers in treatment suggest the growing consideration for intraperitoneal administration of chemotherapeutics and combination of traditional drugs with new ones. Moreover, the necessity to prevent the relapse of the disease leads to the consideration of administering intraperitoneal chemotherapy earlier in the therapeutical algorithm. | Federico Coccolini Giulia Montori Marco Ceresoli Simona Cima Maria Carla Valli Gabriela E Nita Arianna Heyer Fausto Catena Luca Ansaloni | 2016 | World Journal of Gastroenterology2016，22，3： | 25 |
| 2 | Acute appendicitis: Epidemiology, treatment and outcomesanalysis of 16544 consecutive cases显示文摘AIM To investigate the epidemiology,treatment and outcomes of acute appendicitis(AA) in a large population study.METHODS This is a retrospective cohort study derived from the administrative dataset of the Bergamo district healthcare system(more than 1 million inhabitants) from 1997 to 2013.Data about treatment,surgery,length of stay were collected.Moreover for each patients were registered data about relapse of appendicitis and hospital admission due to intestinal obstruction.RESULTS From 1997 to 2013 in the Bergamo district we collected 16544 cases of AA,with a crude incidence rate of 89/100000 inhabitants per year; mean age was 24.51 ± 16.17,54.7% were male and the mean Charlson's comorbidity index was 0.32 ± 0.92.Mortality was < 0.0001%.Appendectomy was performed in 94.7% of the patients and the mean length of stay was 5.08 ± 2.88 d; the cumulative hospital stay was 5.19 ± 3.36 d and 1.2% of patients had at least one further hospitalization due intestinal occlusion.Laparoscopic appendectomy was performed in 48% of cases.Percent of 5.34 the patients were treated conservatively with a mean length of stay of 3.98 ± 3.96 d; the relapse rate was 23.1% and the cumulative hospital stay during the study period was 5.46 ± 6.05 d.CONCLUSION The treatment of acute appendicitis in Northern Italy is slowly changing,with the large diffusion of laparoscopic approach; conservative treatment of non-complicated appendicitis is still a neglected option,but rich of promising results. | Marco Ceresoli Alberto Zucchi Niccolò Allievi Asaf Harbi Michele Pisano Giulia Montori Arianna Heyer Gabriela E Nita Luca Ansaloni Federico Coccolini | 2016 | World Journal of Gastrointestinal Surgery2016，8，10： | 14 |
| 3 | Laparoscopic management of intra-abdominal infections:Systematic review of the literature显示文摘AIM: To investigate the role of laparoscopy in diagnosis and treatment of intra abdominal infections.METHODS: A systematic review of the literature was performed including studies where intra abdominal infections were treated laparoscopically.RESULTS: Early laparoscopic approaches have become the standard surgical technique for treating acute cholecystitis. The laparoscopic appendectomy has been demonstrated to be superior to open surgery in acute appendicitis. In the event of diverticulitis, laparoscopic resections have proven to be safe and effective procedures for experienced laparoscopic surgeons and may be performed without adversely affecting morbidity and mortality rates. However laparoscopic resection has not been accepted by the medical community as the primary treatment of choice. In high-risk patients, laparoscopic approach may be used for exploration or peritoneal lavage and drainage. The successful laparoscopic repair of perforated peptic ulcers for experienced surgeons, is demonstrated to be safe and effective. Regarding small bowel perforations, comparative studies contrasting open and laparoscopic surgeries have not yet been conducted. Successful laparoscopic resections addressing iatrogenic colonic perforation have been reported despite a lack of literature-based evidence supporting such procedures. In post-operative infections, laparoscopic approaches may be useful in preventing diagnostic delay and controllingthe source.CONCLUSION: Laparoscopy has a good diagnostic accuracy and enables to better identify the causative pathology; laparoscopy may be recommended for the treatment of many intra-abdominal infections. | Federico Coccolini Cristian Tranà Massimo Sartelli Fausto Catena Salomone Di Saverio Roberto Manfredi Giulia Montori Marco Ceresoli Chiara Falcone Luca Ansaloni | 2015 | World Journal of Gastrointestinal Surgery2015，7，8： | 5 |
| 4 | The Treatment of Peritoneal Carcinomatosis in Advanced Gastric Cancer: State of the Art显示文摘 | Giulia Montori Federico Coccolini Marco Ceresoli Fausto Catena Nicola Colaianni Eugenio Poletti Luca Ansaloni George H. Sakorafas | 2014 | International Journal of Surgical Oncology2014，，： | 2 |
| 5 | Primary pulmonary meningioma: Report of a case and re- view of the literature 显示文摘 | INCARBONE M CERESOLI GL DI TOMMASO L | 2008 | Lung Cancer2008，62，3： | 1 |
| 6 | Akt phosphorylation and gefitinib efficacy in patients with advanced non-small cell lung cancer 显示文摘 | CAPPUZZO F MARRINI E CERESOLI G L | 2004 | J Natl Cancer Inst2004，96，15： | 1 |
| 7 | Therapeutic outcome according to histologic subtype in 121 patients with malignant pleural mesothelioma显示文摘 | Giovanni Luca Ceresoli Laura Deborah Locati Andrés José Mar??a Ferreri Cesare Cozzarini Paolo Passoni Giulio Melloni Piero Zannini Angelo Bolognesi Eugenio Villa | 2001 | Lung Cancer2001，，2： | 1 |
| 8 | Factors predicting radiation pneumonitis in lung cancer patients:a retrospective study显示文摘 | Rancati T Ceresoli GL Gagliardi G | 2003 | Ratdiother Oncol2003，67，3： | 1 |
| 9 | Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer显示文摘 | Cappuzzo F Magrini E Ceresoli G L | | 0，，5： | 1 |
| 10 | Geefitinib in patients with brain metastases from non-small-cell lung cancer:a prospective trial显示文摘 | Ceresoli GL Cappuzzo F Gregorc V | 2004 | Ann Oncol2004，15，7： | 1 |
| 11 | Water-soluble contrast agent in adhesive small bowel obstruction:a systematic review and meta-analysis of diagnostic and therapeutic value显示文摘 | Ceresoli M Coccolini F Catena F | 2015 | Am J Surg2015，19，12： | 1 |
| 12 | Phase II study ofpemetrexed plus carboplatin in malignant pleural mesothelioma显示文摘 | Ceresoli GL Zucali PA Favaretto AG | 2006 | J Clin Oncol2006，24，9： | 1 |
| 13 | Retreatment with pemetrexed based chemotherapy in patients with malignant pleural mesothelioma显示文摘 | Ceresoli G Zucali PA De Vincenzo F | 2011 | Lung Cancer2011，72，1： | 1 |
| 14 | Pemetrexed plus carbo-platin in elderly patients with malignant pleural mesothelioma: com-bined analysis of two phase II trials显示文摘 | Ceresoli GL Castagneto B Zucali PA* | 2008 | Br J Cancer2008，99，1： | 1 |
| 15 | Brain metastases in locally advanced non small cell lung carcinoma after multimodality treatment : risk factors analysis 显示文摘 | Ceresoli GL Reni M Chiesa G | 2002 | Cancer2002，95，3： | 1 |
| 16 | Factors predicting radiation pneumonitis in lung cancer patients: A retrospective study显示文摘 | Rancati T Ceresoli GL Gagliardi G | 2003 | Radiother Oncol2003，67，： | 1 |
| 17 | Brain metastases in locally advanced nonsmall cell lung carcinoma after multimodality treatment显示文摘 | Ceresoli GL Reni M Chiesa G | | 0，，03： | 1 |
| 18 | QUANTUM ESPRESSO: a modular and open-source software project for quantumsimulations of materials显示文摘 | Paolo Giannozzi Stefano Baroni Nicola Bonini Matteo Calandra Roberto Car Carlo Cavazzoni Davide Ceresoli Guido L Chiarotti Matteo Cococcioni Ismaila Dabo Andrea Dal Corso Stefano de Gironcoli Stefano Fabris Guido Fratesi Ralph Gebauer Uwe Gerstmann Christ | 2009 | Journal of Physics: Condensed Matter2009，，39： | 1 |
| 19 | Factors predicting radia- tion pneumonitis in lung cancer patients : a retrospective study 显示文摘 | Rancati T Ceresoli G L Gagliardi G | 2003 | Ra- diother Onco12003，67，3： | 1 |
| 20 | Factors predic%ing ra-diation pneumonitis in lung cancer patients,A retrospective study显示文摘 | Rancati T Ceresoli GL Gagliardi Q | 2005 | Radiotherapy 0ncoi2005，67，5： | 1 |
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