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| 1 | Incremental age-related one-year MACCE after acute myocardial infarction in the drug-eluting stent era (from KAMIR-NIH registry)显示文摘ObjectivesTo 评估年龄相关的一个年专业在在尖锐心肌的梗塞(AMI ) 的经皮的冠的干预(一种总线标准) 以后的不利 cardiocerebrovascular 事件(MACCE ) 。我们从在 2011 年 11 月之间的健康(KAMIR-NIH ) 的朝鲜尖锐心肌的梗塞登记公民 Institue 在 13,104 个 AMI 病人全部的 AMI.MethodsA 以后分析了在年龄和一个年 MACCE 之间的协会, 2015 年 12 月根据年龄被分类进四个组(组我, < 60 年, n = 4199;组 II, 60-70 年, n = 2577;组织 III;70-80 年, n = 2774;组 IV, 80 年, n = 1018 ) 。病人们为 MACCE 合成的一个年被分析(心脏的死亡,心肌的梗塞,目标容器 revascularization,脑血管的事件) 在 AMI.ResultsThe 一个年以后,在 AMI 的 MACCE 是 3.5%( 组我) , 6.3%( 组 II ) , 9.6%( 组 III ) 并且 17.6%( 组 IV ) 。在为使参数惊讶的调整以后,分析结果证明有 AMI 的病人有一个年 MACCE 的增长风险[组 II,调整危险比率(aHR )= 1.224, 95% CI:0.965-1.525, P = 0.096;组 III, aHR = 1.316, 95% CI:1.037-1.671, P = 0.024;组 IV, aHR = 1.975, 95% CI:1.500-62.601, P < 0.001 ) 与相比组我。特别,心脏的死亡在玩的主要结束点合成在这效果的一个主要角色(组 II, aHR = 1.335, 95% CI:0.941-1.895, P = 0.106;组 III, aHR = 1.575, 95% CI:1.122-2.210, P = 0.009;组 IV, aHR = 2.803, 95% CI:1.937-4.054, P < 0.001 ).ConclusionsDespite 在 AMI 为一种总线标准推进了技术和药,年龄仍然在临床的结果施加强大的影响。小心的途径,甚至在发达心病学的现代时代被需要为在 AMI 干预年老人口。 | Dae-Won Kim Sung-Ho Her Ha Wook Park Kiyuk Chang Wook Sung Chung Ki Bae Seung Myung Ho Jeong Hyo-Soo Kim Hyeon Cheoi Gwon In Whan Seong Kyung Kuk Hwang Shung Chull Chae Kwon-Bae Kim Young Jo Kim Kwang Soo Cha Seok Kyu Oh Jei Keon Chae Ji-Hoon Jung | 2018 | Journal of Geriatric Cardiology2018，15，9： | 4 |
| 2 | Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry显示文摘Background There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention(PCI). Furthermore, gender differences in clinical outcomes with acute myocardial infarction(AMI) following PCI in Asian population remain uncertain because of the under-representation of Asian in previous trials. Methods A total of 13,104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institute of Health(KAMIR-NIH) between November 2011 and December 2015 were classified into male(n = 8021, 75.9%) and female(n = 2547, 24.1%). We compared the demographic, clinical and angiographic characteristics, 30-days and 1-year major adverse cardiac and cerebrovascular events(MACCE) in women with those in men after AMI by using propensity score(PS) matching. Results Compared with men, women were older, had more comorbidities and more often presented with non-ST segment elevation myocardial infarction(NSTEMI) and reduced left ventricular systolic function. Over the median follow-up of 363 days, gender differences in both 30-days and 1-year MACCE as well as thrombolysis in myocardial infarction minor bleeding risk were not observed in the PS matched population(30-days MACCE: 5.3% vs. 4.7%, log-rank P = 0.494, HR = 1.126, 95% CI: 0.800-1.585;1-year MACCE: 9.3% vs. 9.0%, log-rank P = 0.803, HR = 1.032, 95% CI: 0.802-1.328;TIMI minor bleeding: 4.9% vs. 3.9%, log-rank P = 0.215, HR = 1.255, 95% CI: 0.869-1.814). Conclusions Among Korean AMI population undergoing contemporary PCI, women, as compared with men, had different clinical and angiographic characteristics but showed similar 30-days and 1-year clinical outcomes. The risk of bleeding after PCI was comparable between men and women during one-year follow up. | Myunhee Lee Dae-Won Kim Mahn-Won Park Kyusup Lee Kiyuk Chang Wook Sung Chung Tae Hoon Ahn Myung Ho Jeong Seung-Woon Rha Hyo-Soo Kim Hyeon Cheol Gwon In Whan Seong Kyung Kuk Hwang Shung Chull Chae Kwon-Bae Kim Young Jo Kim Kwang Soo Cha Seok Kyu Oh Jei Keon Chae Ji-Hoon Jung 无 KAMIR-NIH registry investigators | 2020 | Journal of Geriatric Cardiology2020，17，11： | 3 |
| 3 | Effect of serum testosterone and percent tumor volume on extra-prostatic extension and biochemical recurrence after laparoscopic radical prostatectomy显示文摘几研究表明了外科手术前的浆液睾丸激素和百分比肿瘤体积(PTV ) 在激进的前列腺切除术以后预言 extra-prostatic 扩展(EPE ) 和生物化学的复发(BCR ) 。这研究在 laparoscopic 激进分子前列腺切除术(LRP ) 以后在与 EPE 和 BCR 的关系调查了浆液睾丸激素和 PTV 的预示的意义。我们考察了经历了在 2004 和 2012 之间的 LRP 的 520 个病人。PTV 在每节作为所有视觉上估计的肿瘤 foci 的和被决定。BCR 被定义为手术后的前列腺特定的抗原(PSA ) 的二连续增加 > 0.2 ng ml 1 。为浆液总数睾丸激素的阀值是 3.0 ng ml 1 。Multivariate 逻辑回归被用来在 EPE 和 BCR 的风险上定义变量的效果。低浆液睾丸激素(< 3.0 ng ml 1) 与高浆液 PSA,格利森分数,前列腺活体检视的积极核心百分比, PTV,和所有病理学的变量被联系。在 multivariate 分析上,类似于以前的研究,浆液 PSA,活体检视积极核心百分比,格利森分数,和病理学的变量预言了 EPE 和 BCR。另外,低浆液睾丸激素(< 3.0 ng ml 1 ,调整或, 8.52;95% CI, 5.04-14.4, P= 0.001 ) 预言的 EPE 和 PTV (调整或, 1.02;95% CI, 1.01-1.05, P= 0.046 ) 预言的 BCR。除了 EPE 和 BCR 的以前的预言者,低浆液睾丸激素和 PTV 在 LRP 以后是 EPE 和 BCR 的珍贵预言者。 | Eu Chang Hwang Seong Hyeon Yu Yang Hyun Jo Seung I1 Jung Taek Won Kang Dong Deuk Kwon Chan Choi Suk Hee Heo Jun Eul Hwang Sung-Hoon Jung Tae-Young Jung | 2016 | Asian Journal of Andrology2016，18，1： | 3 |
| 4 | Highly ordered lead-free double perovskite halides by design显示文摘Lead-free double perovskite halides are emerging optoelectronic materials that are alternatives to leadbased perovskite halides.Recently,single-crystalline double perovskite halides were synthesized,and their intriguing functional properties were demonstrated.Despite such pioneering works,lead-free double perovskite halides with better crystallinity are still in demand for applications to novel optoelectronic devices.Here,we realized highly crystalline Cs2AgBiBr6 single crystals with a well-defined atomic ordering on the microscopic scale.We avoided the formation of Ag vacancies and the subsequent secondary Cs3Bi2Br9 by manipulating the initial chemical environments in hydrothermal synthesis.The suppression of Ag vacancies allows us to reduce the trap density in the as-grown crystals and to enhance the carrier mobility further.Our design strategy is applicable for fabricating other lead-free halide materials with high crystallinity. | Chang Won Ahn Jae Hun Jo Jong Chan Kim Hamid Ullah Sangkyun Ryu Younghun Hwang Jin San Choi Jongmin Lee Sanghan Lee Hyoungjeen Jeen Young-Han Shin Hu Young Jeong Ill Won Kim Tae Heon Kim | 2020 | Journal of Materiomics2020，6，4： | 2 |
| 5 | Sex-based differences in histology,staging,and prognosis among 2983 gastric cancer surgery patients显示文摘BACKGROUND Few studies have been conducted on sex differences in the incidence, pathophysiology, and prognosis of gastric cancer(GC).AIM To analyze the differences in GC characteristics according to sex in patients who underwent surgical treatment for GC.METHODS A total of 2983 patients diagnosed with gastric adenocarcinoma who received surgical treatment at the Seoul National University Bundang Hospital between 2003 and 2017 were included.Baseline clinicopathological characteristics, histologic type of GC, overall and GC-specific survival rates, and associated risk factors were analyzed.RESULTS Among the 2983 patients, 2005(67.2%) and 978(32.8%) were males and females, respectively.The average age of the female group(59.36 years) was significantly younger than that of the male group(61.66 years;P < 0.001).Cancer of the gastric body(P < 0.001) and diffuse-type histology(P < 0.001) were more common in females than in males.This trend was more prominent in females younger than 60 years of age, with a significantly higher proportion of diffuse-type cancer than in the male group.Regardless of sex, diffuse-type GC was more common in younger patients, and the proportion of intestinal-type GC increased with age.The overall survival rate was significantly higher in females(P < 0.001).However, this difference disappeared for GC-specific survival(P = 0.168), except for the poor GC-specific survival rate in advanced-stage cancer(stage Ⅲ or above) in females(P = 0.045).The risk factors for GC-related mortality were older age, upper location of GC, and diffuse-or mixed-type histology.In terms of comorbidities, more males died from diseases other than GC, including other malignancies such as lung cancer, hepatocellular carcinoma, and pancreatic cancer, and respiratory diseases such as interstitial lung disease and chronic obstructive pulmonary disease, while there were relatively more cardiovascular or cerebrovascular deaths in females.CONCLUSION Sex-based differences in GC were observed in clinicopathological features, including age at diagnosis, tumor location, histologic type, survival rate, and comorbidities. | Yonghoon Choi Nayoung Kim Ki Wook Kim Hyeong Ho Jo Jaehyung Park Hyuk Yoon Cheol Min Shin Young Soo Park Dong Ho Lee Hyeon Jeong Oh Hye Seung Lee Young Suk Park Sang-Hoon Ahn Yun-Suhk Suh Do Joong Park Hyung-Ho Kim Ji-Won Kim Jin Won Kim Keun-Wook Lee Won Chang Ji HoonPark Yoon Jin Lee Kyoung Ho Lee Young Hoon Kim | 2022 | World Journal of Gastroenterology2022，28，9： | 2 |
| 6 | Model for predicting and phenotyping at normal weight the long-term propensity for obesity in Sprague-Dawley rats显示文摘 | DOURMASHKIN JT CHANG GQ HILL JO | 2006 | Physiol Behav2006，87，4： | 1 |
| 7 | Improved detection of ischeniie heart disease by combining high-frequency eleetrocar~ogram ana- lysis with exercise stress echocardiography 显示文摘 | Choi JO Chang SA Park SJ | 2013 | Korean Circ J2013，43，10： | 1 |
| 8 | 食用菌与人类健康(一)显示文摘2013年9月9~10日,美国蘑菇理事会在华盛顿召开食用菌与健康峰会。会议指出,将食用菌定位为健康食品和养生保健品的研究主要集中于最近的几十年。中国是最早栽培食用菌的国家,目前仍然和美国、意大利、荷兰、波兰一样,是全球食用菌生产大国之一。虽然在饮食上,食用菌被认为是一种蔬菜,但它是一种真菌,区别在于食用菌中含量极低的维生素B12的存在形式与肉类的相同,麦角固醇能通过紫外光照转换为维生素D2和共轭亚油酸。食用菌是麦角硫因(存在于自然界的一种稀有氨基酸,在机体内具有重要的生理活性)的罕见来源,同时含有硒、纤维素及其他维生素和矿物质。一些临床前和临床试验,研究了食用菌对认知能力、体重管理、口腔健康和患癌几率的影响。初步证据表明,食用菌可能通过与肠道菌群的互动,提供良好的免疫和炎症反应,增强适应性免疫的发展和改进免疫细胞功能。除了直接提供营养和健康福祉之外,美国食物摄入量调查数据的分析表明,食用菌还与更高的膳食质量有关。早期的感官研究表明,食用菌与肉类和低钠菜肴混合很受欢迎,在不影响口味的情况下可能有助于减少红色肉类(牛、羊肉等)和盐的摄入。食用菌特定的健康效应研究进展表明,需要通过有效的沟通交流,实现利用食用菌来提高整体饮食质量的目标。. | Mary Jo Feeney Johanna Dwyer Clare M.Hasler-Lewis John A.Milner Manny Noakes Sylvia Rowe Mark Wach Robert B.Beelman Joe Caldwell Margherita T.Cantorna Lisa A.Castlebury Shu-Ting Chang Lawrence J.Cheskin Roger Clemens Greg Drescher Victor L.Fulgoni Ⅲ David B.Haytowitz Van S.Hubbard David Law Amy Myrdal Miller Bart Minor Susan S.Percival Gabriela Riscuta Barbara Schneeman Suzanne Thornsbury Cheryl D.Toner Catherine E.Woteki Dayong Wu 郑玲 | 2015 | 食药用菌2015，23，2： | 1 |
| 9 | An uncaught exception analysis for Java 显示文摘 | Jang-Wu Jo Byeong-Mo Chang | 2004 | Journal of Systems and Software:2004，72，1： | 1 |
| 10 | Moving away or fitting in? Understanding shyness in Chi- nese children显示文摘 | Xu Yiyuan Farver Jo Ann M Chang Lei | 2007 | Merrill-Palmer Quarterly2007，53，4： | 1 |
| 11 | Hydrogen production with immobilized sewage sludge in three-phase fluidized-bed bioreactors显示文摘 | Wu Shu Yii Lin Chi Num Chang Jo Shu | 2003 | Biotechnol Prog2003，19，3： | 1 |
| 12 | Global soft decision employing support vector machine for speech enhancement 显示文摘 | Chang J H Jo Q H Kim D K at al | 2008 | IEEESignal Process Lett2008，16，1： | 1 |
| 13 | Improved detection of ische- mie heart disease by combining high-frequency electrocardiogram analysis with exereise stress echocardiography 显示文摘 | Choi JO Chang SA Park SJ | 2013 | Korean Cite J2013，43，10： | 1 |
| 14 | Ursolic acid regulates high glu cose -induced apoptosis 显示文摘 | Chang JO In SK Chan IP | 2007 | Free Radical Res2007，41，6： | 1 |
| 15 | Epicardial induction of fetal cardiomyo- cyte proliferation via a retinoic acid-inducible trophic factor 显示文摘 | Chen TH Chang TC Kang JO | 2002 | Dev Biol2002，250，： | 1 |
| 16 | A Co-Operative Study: Clinical Characteristics of 334 Korean Patients with Moyamoya Disease Treated at Neurosurgical Institutes (1976–1994)显示文摘 | Dae Hee Han O-Ki Kwon Bark Jang Byun Byung Yeon Choi Chang Wha Choi Joong Uhn Choi Seon Gil Choi Jong Oung Doh Jong Woo Han Shin Jung Sung Don Kang Dae Jo Kim Hyoung-Ihl Kim Hyung Dong Kim Moon Chul Kim Sang Chul Kim Soo Chun Kim Youn Kim Byung Duk Kwun B | 2000 | Acta Neurochirurgica2000，，11： | 1 |
| 17 | High-level expression of an antimicrobial peptide histonin as a natural form by multimerization and furin-mediated cleavage显示文摘 | Jung Min Kim Su A Jang Byung Jo Yu Bong Hyun Sung Ju Hyun Cho Sun Chang Kim | 2008 | Applied Microbiology and Biotechnology2008，，1： | 1 |
| 18 | Luminescence properties of Eu-doped SnO 2显示文摘 | Sung-Sik Chang M.S. Jo | 2006 | Ceramics International2006，，4： | 1 |
| 19 | Decolorization of azo dyes with immobilized Pseudomonas luteola显示文摘 | Jo - shu Chang | 2001 | Process Biochemistry2001，36，9： | 1 |
| 20 | Global soft decision employing support vector machine for speech enhancement显示文摘 | Chang J H Jo Q H Kim D K etal | 2009 | IEEE Signal Processing Letters2009，16，1： | 1 |
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