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| 1 | A non-destructive method to measure the thermal properties of frozen soils during phase transition显示文摘Frozen soils cover about 40%of the land surface on the earth and are responsible for the global energy balances affecting the climate.Measurement of the thermal properties of frozen soils during phase transition is important for analyzing the thermal transport process.Due to the involvement of phase transition,the thermal properties of frozen soils are rather complex.This paper introduces the uses of a multifunctional instrument that integrates time domain re fl ectometry(TDR)sensor and thermal pulse technology(TPT)to measure the thermal properties of soil during phase transition.With this method,the extent of phase transition(freezing/thawing)was measured with the TDR module;and the corresponding thermal properties were measured with the TPT module.Therefore,the variation of thermal properties with the extent of freezing/thawing can be obtained.Wet soils were used to demonstrate the performance of this measurement method.The performance of individual modules was fi rst validated with designed experiments.The new sensor was then used to monitor the properties of soils during freezing e thawing process,from which the freezing/thawing degree and thermal properties were simultaneously measured.The results are consistent with documented trends of thermal properties variations. | Bin Zhang Chanjuan Han Xiong(Bill) Yu | 2015 | Journal of Rock Mechanics and Geotechnical Engineering2015，7，2： | 2 |
| 2 | Bioprosthetic Valve Size Selection to Optimize Aortic Valve ReplacementSurgical Outcome: A Fluid-Structure Interaction Modeling Study显示文摘Aortic valve replacement(AVR)remains a major treatment option for patients with severe aortic valve disease.Clinical outcome of AVR is strongly dependent on implanted prosthetic valve size.Fluid-structure interaction(FSI)aortic root models were constructed to investigate the effect of valve size on hemodynamics of the implanted bioprosthetic valve and optimize the outcome of AVR surgery.FSI models with 4 sizes of bioprosthetic valves(19(No.19),21(No.21),23(No.23)and 25 mm(No.25))were constructed.Left ventricle outflow track flow data from one patient was collected and used as model flow conditions.Anisotropic Mooney–Rivlin models were used to describe mechanical properties of aortic valve leaflets.Blood flow pressure,velocity,systolic valve orifice pressure gradient(SVOPG),systolic cross-valve pressure difference(SCVPD),geometric orifice area,and flow shear stresses from the four valve models were compared.Our results indicated that larger valves led to lower transvalvular pressure gradient,which is linked to better post AVR outcome.Peak SVOPG,mean SCVPD and maximum velocity for Valve No.25 were 48.17%,49.3%,and 44.60%lower than that from Valve No.19,respectively.Geometric orifice area from Valve No.25 was 52.03%higher than that from Valve No.19(1.87 cm2 vs.1.23 cm2).Implantation of larger valves can significantly reduce mean flow shear stress on valve leaflets.Our initial results suggested that larger valve size may lead to improved hemodynamic performance and valve cardiac function post AVR.More patient studies are needed to validate our findings. | Caili Li Dalin Tang Jing Yao Christopher Baird Haoliang Sun Chanjuan Gong Luyao Ma Yanjuan Zhang Liang Wang Han Yu Chun Yang Yongfeng Shao | 2021 | Computer Modeling in Engineering & Sciences2021，，4： | 1 |
| 3 | Efficient hydrogenation of ethylene carbonate derived from CO_(2) to synthesize methanol and ethylene glycol over core-shell Cu@GO catalyst显示文摘The synthesis of sustainable methanol and ethylene glycol(EG)via hydrogenation of ethylene carbonate(EC)has caught researchers’growing interests on account of the indirect chemical utilization of CO_(2).Core-shell Cu@GO catalysts with random nanoporous network of graphite oxide(GO)were synthesized via a simple method of ul-trasonic precipitation.Cu@GO catalysts were analyzed systematically by N_(2) physisorption,TGA measurement,XRD,FT-IR,Raman,TEM,SEM,and XPS(XAES).In particular,the mentioned method was confirmed to be effective to fabricate the high dispersity core-shell Cu@GO catalysts through promoting the specific surface area.The as-prepared Cu@GO catalyst was then successfully applied in the hydrogenation of CO_(2)-derived EC to pro-duce methanol and EG.A high TOF of 1526 mg EC g cat^(-1) h^(-1) could be attained in EC hydrogenation at the reaction temperature of 493K.Accordingly,the correlation of catalytic structure and performance disclosed that the synergistic effect between Cu^(+) and Cu^(0) was responsible for achieving high activity of the catalyst.In addition,the reusability of Cu@GO catalyst suggested that graphite oxide shell structure could decrease the aggregation of Cu particles,thus enhance the stability of Cu-based catalysts.DFT calculation results suggested that the involvement of carbon film on Cu was favorable for the stabilization of the active sites.This study is helpful for developing new and stable catalytic system for indirect chemical utilization of CO_(2) to synthesize commodity methanol and EG. | Chanjuan Zhang Liguo Wang Zhuo Han Peng He Yan Cao Jiachen Li Huiquan Li | 2022 | Green Chemical Engineering2022，3，3： | 1 |
| 4 | Esophageal intraluminal baseline impedance is associated with severity of acid reflux and epithelial structural abnormalities in patients with gastroesophageal reflux disease显示文摘 | Chanjuan Zhong Liping Duan Kun Wang Zhijie Xu Ying Ge Changqing Yang Yajing Han | 2013 | Journal of Gastroenterology2013，，5： | 1 |
| 5 | USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency显示文摘The homeobox transcription factor Nanog has a vital role in maintaining pluripotency and self-renewal of embryonic stem cells(ESCs).Stabilization of Nanog proteins is essential for ESCs.The ubiquitin–proteasome pathway mediated by E3 ubiquitin ligases and deubiquitylases is one of the key ways to regulate protein levels and functions.Although ubiquitylation of Nanog catalyzed by the ligase FBXW8 has been demonstrated,the deubiquitylase that maintains the protein levels of Nanog in ESCs yet to be defined.In this study,we identify the ubiquitin-specific peptidase 21(USP21)as a deubiquitylase for Nanog,but not for Oct4 or Sox2.USP21 interacts with Nanog protein in ESCs in vivo and in vitro.The C-terminal USP domain of USP21 and the C-domain of Nanog are responsible for this interaction.USP21 deubiquitylates the K48-type linkage of the ubiquitin chain of Nanog,stabilizing Nanog.USP21-mediated Nanog stabilization is enhanced in mouse ESCs and this stabilization is required to maintain the pluripotential state of the ESCs.Depletion of USP21 in mouse ESCs leads to Nanog degradation and ESC differentiation.Overall,our results demonstrate that USP21 maintains the stemness of mouse ESCs through deubiquitylating and stabilizing Nanog. | Xingyu Liu Yuying Yao Huiguo Ding Chuanchun Han Yuhan Chen Yuan Zhang Chanjuan Wang Xin Zhang Yiling Zhang Yun Zhai Ping Wang Wenyi Wei Jing Zhang Lingqiang Zhang | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 1 |
| 6 | Impact of Cold Spells on Ischemic Stroke Severity and Clinical Outcomes in Tianjin, China显示文摘There are several studies on the impact of extreme weather on the incidence and mortality of stroke, but the research on the effect of extreme weather events on severity and outcome of ischemic stroke is scarce. This study aimed to evaluate the impact of cold spells on the severity and clinical outcomes of patients with initial acute ischemic stroke in a hospital-based study. We enrolled 553 patients with initial ischemic stroke during the cold seasons between 2016 and 2019. Patients were separated into the mild stroke group and moderate-to-severe stroke group according to the National Institutes of Health Stroke Scale(NIHSS) of the U.S., and good outcome group and poor outcome group according to modified Rankin Scale(mRS) scores. There are nine different definitions of cold spells according to intensities and duration time. After adjustment for climate factors, air quality index, and common risk factors, it is found that cold spells were associated with moderate-to-severe neurological deficits and clinical outcomes in overall ischemic stroke patients. Furthermore, the delay effect for stroke severity started at the beginning of the cold wave(Lag 0) and lasted up to 14 days(Lags 0–14). In addition, when a cold spell was set as a daily mean temperature < 3rd or 5th percentile and with a duration ≥ 2 or 3 consecutive days, cold spells had a significant impact on clinical outcomes, and there was a definite delay effect of at least 7 days(Lags 0–7) and it lasted up to 14days(Lags 0–14). At last, we concluded that cold spells may be a contributory factor for more severe neurological deficits and worse outcomes in patients with initial ischemic stroke. | Juanjuan XUE Chanjuan WEI Xiaoshuang XIA Xuemei QI Yumeng GU Zhongyan WANG Suqin HAN Lin WANG Xin LI | 2023 | Journal of Meteorological Research2023，37，4： | 0 |
| 7 | Effects of Different Hardeners on the Working Properties and Bonding Strength of Urea-formaldehyde Adhesives显示文摘The addition of a hardener is necessary for the curing of urea-formaldehyde (UF) adhesives in the production of MDF and particleboard. The most commonly used hardener, ammonium chloride, however, is suspected to cause the formation of poisonous dioxin when waste boards are combusted and hence considered as a potential source of pollution. To assess the feasibility of substituting ammonium sulphate for ammonium chloride, working properties and bonding strength were measured for UF adhesives with the two ... | YIN Suzhou TANG Chanjuan HAN ShuguangCollege of Wood Science and Technology. Nanjing Forestry University Naniine 210037. P. R. China | 2003 | Chinese Forestry Science and Technology2003，2，3： | 0 |
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