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| 1 | Effects of bile reflux and intragastric microflora changes on lesions of remnant gastric mucosa after gastric operation显示文摘AIM: To investigate the effects of bile reflux and intragastric microflora changes on lesions of remnant gastric mucosa after gastric operation.METHODS: Concenration of bile acid and total bacterial counts (TBC) in gastric juice were measured in 49 patients with peptic ulcer before and after gastrectomy. One year after the operation, sample of gastric mucosa taken from all the patients were used for histological examination.RESULTS: The concentration of gastric bile acid was significantly increased in group B-I, or B-II and SV+A than that in group HSV (P<0.05-0.01). The abnormal histological changes in the remnant gastric mucosa were more common in the first 2 groups than in the last group.CONCLUSION: The type of gastrtectomy can affect bile reflux. The abnormal histological changes in the remnant gastric mucosa are closely related to the elevation of bile acid concentration and increase of TBC in gastric juice. HSV can effectively prevent bile reflux and keep the gastric physiological functions stable. | ChaoZhang Zhan-KuiLiu Pei-WuYu | 2004 | World Journal of Gastroenterology2004，10，10： | 12 |
| 2 | Extraction of protoporphyrin disodium and its inhibitory effects on HBV-DNA显示文摘AIM:To explore an ideal method for extracting protoporphyrin disodium (PPN) from unanticoagulated animal blood, and to study the inhibitory effects of PPN on HBV-DNA duplication and its cytotoxicity to 2.2.15 cell strain.METHODS:Protoporphyrin methyl ester and other intermediate products were prepared with protoheme separated from protein hydrolysates of coagulated animal blood, which were finally made into PPN and detected quantitatively with an ultraviolet fluorescent analyzer.Ten μg/ml, 20μg/ml, 40μg/ml, 80μg/ml and 160μg/ml of PPN-aqueous solution were added into culture medium for 2.2.15 cells respectively. Eight days later, the drug concentration in supernatant from the culture medium was detected when inhibition rate of HBeAg, cell survival rate when inhibition rate of HBeAg was 50% (ID50), and when survival cells in experimental group were 50% of those in control group (CD50), and the therapeutic index (TI) was also detected. PPN with different concentration of 10μg/ml,20μg/ml, 40μg/ml, 80μg/ml and 160μg/ml was respectively mixed and cultivated with HepG2 2.2.15 cell suspension,and then the inhibition of PPN against HBV-DNA was judged by PCR.RESULTS:The extract of henna crystal was identified to be PPN. When the concentrations of PPN were 160μg/ml and 80μg/ml, the inhibition rates of HBeAg were 89.8% and 82.4%, and the cell survival rates were 98.7% and 99.2%.CONCLUSION:It is suggested that PPN can be extracted from unanticoagulated animal blood. PPN can inhibit HBV-DNA expression and duplication in vitro, and has no cytotoxicity to liver cells. Further study and application of PPN are warranted. | Chao-PinLi Li-FaXu Qun-HongLiu ChaoZhang JianWang Yu-XiaZhu | 2004 | World Journal of Gastroenterology2004，10，3： | 8 |
| 3 | Gene therapy for gastric cancer: A review显示文摘Gastric cancer is common in China, and its early diagnosis and treatment are difficult. In recent years great progress has been achieved in gene therapy, and a wide array of gene therapy systems for gastric cancer has been investigated. The present article deals with the general principles of gene therapy and then focuses on how these principles may be applied to gastric cancer. | ChaoZhang Zhan-KuiLiu | 2003 | World Journal of Gastroenterology2003，9，11： | 6 |
| 4 | Three-dimensional nitrogen-doped graphene hydrogel supported Co-CeOx nanoclusters as efficient catalysts for hydrogen generation from hydrolysis of ammonia borane显示文摘The development of highly active noble-metal-free catalysts for catalytic hydrolysis of ammonia borane is mandatory for its application in hydrogen storage.Herein,Co-CeO_xnanoclusters have been successfully anchored on a three-dimensional nitrogen-doped graphene hydrogel(NGH)by a simple coreduction method and further used as efficient catalysts to catalytic hydrolysis of ammonia borane at room temperature.Thanks to the strong synergistic electronic effect between Co and CeO_x,as well as the strong metal-support interaction between Co-CeO_xand 3D NGH,the as-synthesized Co-(CeO_x)_(0.91)/NGH catalyst exhibits superior catalytic activity toward hydrolysis of ammonia borane,with the turnover frequency(TOF)value of 79.5 min^(-1),which is almost 13 times higher than that of Co/NGH,and higher than most of the reported noble-metal-free catalysts. | Yana Men Jun Su Chaozhang Huang Lijing Liang Ping Cai Gongzhen Cheng Wei Luo | 2018 | Chinese Chemical Letters2018，29，11： | 3 |
| 5 | Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus显示文摘特定的 proteinprotein 相互作用为生物信号 transduction 是重要的。postsynaptic density-95,圆盘大,并且 zonulin-1 (PDZ ) 领域是最丰富的蛋白质相互作用模块之一。(MUPP1 ) 作为支架蛋白质, Multi-PDZ-domain 蛋白质 1 包含 13 个 PDZ 领域并且在细胞骨架组织,房间极性,和房间增长起一个重要作用。MUPP1 的 PDZ 领域上的学习帮助理解 MUPP1 的机制和功能。在现在的学习,从亩 musculus 的 MUPP1 (MUPP1-PDZ4 ) 的第四个 PDZ 领域被克隆,表示,净化,并且描绘。MUPP1-PDZ4 领域是进宠物向量的 subcloned 并且在 Escherichia 表示了 coli。亲密关系层析和尺寸排除层析被用来净化蛋白质。MUPP1-PDZ4 蛋白质是有在答案的 16.4 kDa 的一个臼齿的团的单体并且让融化 60.3he 削尖 diffe 褄?褄 的主要决定因素吗?? | Haili.Zhu Zexu Liu Yuxin Huang ChaoZhang Gang Li Wei Liu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，3： | 1 |
| 6 | Speciation of aluminum in drink samples by 8-hydroxyquinoline loaded silylanization silica gel microcolumn separation with off-line ICP- MS detection 显示文摘 | CHEN Jie HUANG Chaozhang HU Bin | 2004 | J Agric Food Chem2004，52，23： | 1 |
| 7 | One‐Step Ionic‐Liquid‐Assisted Electrochemical Synthesis of Ionic‐Liquid‐Functionalized Graphene Sheets Directly from Graphite显示文摘 | NaLiu FangLuo HaoxiWu YinghuiLiu ChaoZhang JiChen | 2008 | Adv Funct Mater2008，，10： | 1 |
| 8 | The Security Assessment of General Anesthesia in Children with Mild to Moderate Upper Respiratory Tract Infection显示文摘 | Juan Li Zhao-qiong Zhu De-xing Liu ChaoZhang Shu-wen Zheng | 2013 | 麻醉与监护论坛2013，20，4： | 1 |
| 9 | Separation/preconcentration of trace amounts of Cr, Cu and Pb in environmental samples by magnetic solid-phase extraction with Bismuthiol-II-immobilized magnetic nanoparticles and their determination by ICP-OES显示文摘 | Jibrin Sabo Suleiman Bin Hu Hanyong Peng Chaozhang Huang | 2008 | Talanta2008，，5： | 1 |
| 10 | Silica-coated magnetic nanopar- ticles modified with 7-mercaptopropyltrimethoxysilane for fast and selective solid phase extraction of trace amounts of Cd, Cu, Hg, and Pb in environmental and biological sam- ples prior to their determination by inductively coupled plas- ma mass spectrometry 显示文摘 | Huang Chaozhang Hu Bin | 2008 | Spectrochimi Acta Part B2008，63，： | 1 |
| 11 | Simultaneous on line preconcentration and determination of trace metals in environmental samples using a modified nanometer-sized alumina packed micro-column by flow injection combined with ICP-OES显示文摘 | Chaozhang Huang Bin Hu Zucheng Jiang | 2007 | Talanta2007，71，： | 1 |
| 12 | Speciationof aluminum in drink samples by 8-hydroxyquinolineloaded silylanization silica gel microcolumn separationwith off-line ICP-MS detection显示文摘 | Chen Jie Huang Chaozhang Hu Bin | 2004 | J Agric FoodChem2004，52，23： | 1 |
| 13 | Speciation of inorganic arsenic in environmental waters using magnetic solid phase extraction and preconcentration followed by ICP- MS 显示文摘 | Huang Chaozhang Xie Wei Li Xiong | 2011 | Microchim Acta2011，173，： | 1 |
| 14 | Separation/preconcentration of trace amounts of Cr, Cu and Pb in environmental samples by magnetic solid-phase extraction with Bismuthiol-II-immobilized magnetic nanoparticles and their determination by ICP-OES显示文摘 | Jibrin Sabo Suleiman Bin Hu Hanyong Peng Chaozhang Huang | 2008 | Talanta2008，，5： | 1 |
| 15 | ICP-AES determinat, on of trace rare earth elements in environmental and food samples by on-line separation and preconcentration with acetylacetone-modified silica gel using microcolumn 显示文摘 | Zhang Nan Huang Chaozhang Hu Bin | 2007 | Anal Sci2007，23，8： | 1 |
| 16 | One‐Step Ionic‐Liquid‐Assisted Electrochemical Synthesis of Ionic‐Liquid‐Functionalized Graphene Sheets Directly from Graphite显示文摘 | NaLiu FangLuo HaoxiWu YinghuiLiu ChaoZhang JiChen | 2008 | Adv Funct Mater2008，，10： | 1 |
| 17 | ICP-AES Determination of Trace Rare Earth Elements in Environmental and Food Samples by On-line Separation and Preeoncentration with Acetylacetonemodified Silica Gel Using Microcolumn显示文摘 | Nan Zhang Chaozhang Huang BinHu | 2007 | AnalyticalSciences2007，23，： | 1 |
| 18 | ICP-AESdeterminat, on of trace rare earth elements in environmental and food samples by on-line separation and preconcentration with acetylacetone-modified silica gel using microcolumn显示文摘 | ZhangNan Huang Chaozhang HuBin | 2007 | Anal Sci2007，23，8： | 1 |
| 19 | Journal of Mass Spectrometry显示文摘 | Huang Chaozhang Hu Bin He Man | 2008 | 43: 3362008，43，： | 1 |
| 20 | Simultaneous on-line preconcentration and determination of trace metals in environmental samples using a modified nanometer-sized alumina packed micro-column by flow injection combined with ICP-OES显示文摘 | Hang Chaozhang Hu Bin Jiang Zucheng | 2007 | Talanta2007，71，3： | 1 |
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