|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | BRIF and CARIF progress显示文摘China Institute of Atomic Energy (CIAE) is currently constructing Beijing rare ion beam facility (BRIF) and is proposing China advanced rare ion beam facility (CARIF). This paper is aiming at introducing the progress of BRIF project and the con ceptual design CARIF. The ISOL type facility BRIF under construction is composed of a 100 MeV 300 ?A proton cyclotron, an ISOL with mass resolution of 20000, and a super-conducting LINAC of 2 MeV/q, and will be commissioned in 2013. CARIF facility proposed is planned to use both ISOL and PF techniques. It is based on a China advanced research reactor CARR that was critical, with ISOL separation of fission fragment, post acceleration to 150 MeV/u, and fragmentation of neu tron-rich fission fragment beam like 132Sn. Such unique combination will allow CARIF to deliver beam intensity better than the best world facilities by more than one order of magnitude. | LIU WeiPing, LI ZhiHong, BAI XiXiang, WANG YouBao, GUO Bing, PENG ChaoHua, YANG Yi, SU Jun, CUI BaoQun, ZHOU ShuHua, ZHU ShengYun, XIA HaiHong, GUAN XiaLing, ZENG Sheng, ZHANG HuanQiao, CHEN YongShou, TANG HongQing, HUANG Li & FENG BeiYuan China Institute of Atomic Energy, P. O. Box 275(1), Beijing 102413, China | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S1： | 8 |
| 2 | Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression,evoking oxidative stress,and activating inflammation and apoptosis显示文摘Background:The immune system is one aspect of health that is affected by dietary selenium(Se)levels and selenoprotein expression.Spleen is an important immune organ of the body,which is directly involved in cellular immunity.However,there are limited reports on Se levels and spleen health.Therefore,this study established a Se-deficient pig model to investigate the mechanism of Se deficiency-induced splenic pathogenesis.Methods:Twenty-four pure line castrated male Yorkshire pigs(45 days old,12.50±1.32 kg,12 full-sibling pairs)were divided into two equal groups and fed Se-deficient diet(0.007 mg Se/kg)or Se-adequate diet(0.3 mg Se/kg)for 16 weeks.At the end of the trial,blood and spleen were collected to assay for erythroid parameters,the osmotic fragility of erythrocytes,the spleen index,histology,terminal deoxynucleotidyl transferase nick-end labeling(TUNEL)staining,Se concentrations,the selenogenome,redox status,and signaling related inflammation and apoptosis.Results:Dietary Se deficiency decreased the erythroid parameters and increased the number of osmotically fragile erythrocytes(P<0.05).The spleen index did not change,but hematoxylin and eosin and TUNEL staining indicated that the white pulp decreased,the red pulp increased,and splenocyte apoptosis occurred in the Se deficient group.Se deficiency decreased the Se concentration and selenoprotein expression in the spleen(P<0.05),blocked the glutathione and thioredoxin antioxidant systems,and led to redox imbalance.Se deficiency activated the NF-κB and HIF-1αtranscription factors,thus increasing pro-inflammatory cytokines(IL-1β,IL-6,IL-8,IL-17,and TNF-α),decreasing anti-inflammatory cytokines(IL-10,IL-13,and TGF-β)and increasing expression of the downstream genes COX-2 and iNOS(P<0.05),which in turn induced inflammation.In addition,Se-deficiency induced apoptosis through the mitochondrial pathway,upregulated apoptotic genes(Caspase3,Caspase8,and Bak),and downregulated antiapoptotic genes(Bcl-2)(P<0.05)at the mRNA level,thus verifying the results of TUNEL staining.Conclusions:These results indicated that Se deficiency induces spleen injury through the regulation of selenoproteins,oxidative stress,inflammation and apoptosis. | Shuang Li Wenjuan Sun Kai Zhang Jiawei Zhu Xueting Jia Xiaoqing Guo Qingyu Zhao Chaohua Tang Jingdong Yin Junmin Zhang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 4 |
| 3 | Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair显示文摘连接器 histone H1 在 DNA 损坏反应是更高的顺序染色质结构,而是它的参与的一个主人管理者,修理是不清楚的。这里,我们报导连接器 histone H1.2 是混乱毛细管扩张的一个必要管理者变异(ATM ) 激活。我们证明 H1.2 通过和 ATM 热重复领域和 MRE11-RAD50-NBS1 (MRN ) 的抑制的直接相互作用保护染色质免受异常 ATM 激活的伤害复杂依赖者的 ATM 招募。在 DNA 损坏之上, H1.2 通过它的 C 终点和进一步的 proteasomal 降级的 poly-ADP-ribosylation (PARylation ) 经历快速的 PARP1 依赖的染色质分离。由 PARylation 死了的变化妥协 ATM 激活和 DNA 损坏修理的 PARP1 弄空或 H1.2 的 H1.2 排水量的抑制,因此导致损害了房间幸存。一起拿,我们的调查结果建议连接器 histone H1.2 作为一个生理的障碍工作因为指向染色质的 ATM,和调停 PARylation 的活跃 H1.2 周转为柔韧的 ATM 激活和 DNA 损坏修理被要求。 | Zhiming Li Yinglu Li Ming Tang Bin Peng Xiaopeng Lu Qiaoyan Yang Qian Zhu Tianyun Hou Meiting Li Chaohua Liu Lina Wang Xingzhi Xu Ying Zhao Haiying Wang Yang Yang Wei-Guo Zhu | 2018 | Cell Research2018，28，7： | 3 |
| 4 | An improved Z- source inverter 显示文摘 | TANG Yu XIE Shaojun ZHANG Chaohua | 2011 | IEEE Transactions on Power Electronics2011，26，12： | 1 |
| 5 | Improved Z-source inverter with reduced Z-source capacitor voltage stress and soft-start capability 显示文摘 | Tang Yu Xie Shaojun Zhang Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 6 | Improved Z-source inverter with reduced Z-source capacitor voltage stress and soft -start capability显示文摘 | TANG Yu XIE Shaojun ZHANG Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 7 | Improved Z-Sourceinverter with reduced Z-Source capacitor voltage stress and soft-startcapability显示文摘 | Yu Tang Shaojun Xie Chaohua Zhang | 2009 | Transactions on Power Electronics2009，24，2： | 1 |
| 8 | Im reduced Z-source capacitor voltage stress and so{t-start capability 显示文摘 | Tang Yu Xie Shaojun Zhang proved Z-source inverter with Chaohua | 2009 | IEEE Transaction on Power Electronics2009，24，2： | 1 |
| 9 | Improved Zsource inverter with reduced Z-source capacitor voltage stress and soft-start capability显示文摘 | TANG Yu XIE Shaojun ZHANG Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 10 | Preparation of immobilized glucose oxidase and its application in improving breadmaking quality of commercial wheat flour显示文摘 | Lele Tang Ruijin Yang Xiao Hua Chaohua Yu Wenbin Zhang Wei Zhao | 2014 | Food Chemistry2014，，： | 1 |
| 11 | A rapid shoot regeneration protocol from the cotyledons of hemp ( Cannabis sativa L.)显示文摘 | Cheng Chaohua Zang Gonggu Zhao Lining Gao Chunsheng Tang Qing Chen Jianhua Guo Xinbo Peng Dingxiang Su Jianguang | 2016 | Industrial Crops & Products2016，，： | 1 |
| 12 | Improved Z-Source Inverter with Reduced Z-Source Capacitor Voltage Stress and Soft-Start Capability显示文摘 | Tang Yu Xie Shaojun Zhang Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 13 | Improved Z- source inverter with reduced Z-source capacitor voltage stress and soft-start capability显示文摘 | Tang Yu Xie Shaojun Zhang Chaohua | 2009 | EEE Transactions onPower Electronics2009，24，2： | 1 |
| 14 | Carotenoid enrichment in eggs:From biochemistry perspective显示文摘The emergence of safe and functional eggs for consumer acceptance has gained focus.The production of carotenoid-enriched eggs has received attention due to its multifunctional biological properties.Nutritional modification of laying hens’diet can be a strategy to produce such eggs.This review presents the chemistry of carotenoids in nature and eggs,the accumulation process of carotenoids into eggs,and the functions of carotenoids in eggs.Our findings showed that carotenoids can be deposited into the egg and contribute to improving its nutritive value.The biosynthesis,chemical structure,and metabolism pathways of carotenoids lead to the deposition of carotenoids into eggs in their original or metabolized forms.Also,some factors modulate the efficiency of carotenoids in fowls before accumulation into eggs.Carotenoid-enriched eggs may be promising,ensuring the availability of highly nutritive eggs.However,further studies are still needed to comprehend the full metabolism process and the extensive functions of carotenoids in eggs. | Dieudonne M.Dansou Huiyan Zhang Yanan Yu Hao Wang Chaohua Tang Qingyu Zhao Yuchang Qin Junmin Zhang | 2023 | Animal Nutrition2023，，3： | 0 |
| 15 | Effects of iron oxide nanoparticles on phenotype and metabolite changes in hemp clones(Cannabis sativa L.)显示文摘We investigated the effect of iron oxide nanoparticles(Fe_(3)O_(4)NPs,~17 nm in size)on the phenotype and metabolite changes in hemp(Cannabis sativa L.),an annual crop distributed worldwide.Hemp clones were grown in hydroponic cultures with Fe_(3)O_(4)NPs(50,100,200,or 500 mg/L)for four weeks.TEM and ICP-MS were used to determine Fe_(3)O_(4)NPs uptake and translocation.LC-MS-based metabolomics was employed to explore the deep insight into the effect of Fe_(3)O_(4)NPs on hemp plants.The results revealed that plant growth enhanced gradually with increasing concentrations of given NPs up to 200 mg/L,which improved the fresh weight and dry weight by 36.13%and 74.68%,respectively,compared to the control.Even at a high dose(500 mg/L),Fe_(3)O_(4)NPs promoted plant growth,including increased biomass and tissue length.NPs significantly increased the iron and chlorophyll content in plant tissues Increased catalase activity and reduced hydrogen peroxide content in hemp leaves suggested that the Fe_(3)O_(4)NPs activated the defense system.TEM showed that NPs were abundantly attached to the cell wall and dispersed throughout the root cells.Metabolomics revealed that Fe_(3)O_(4)NPs induced metabolic reprogramming in hemp leaves,including the up-regulation of carbohydrates and organic acids,and down-regulation of antioxidants,especially tetrahydrocannabinol(THC).The significantly up-regulated metabolites,including peonidin and 2-hydroxycinnamic acid,could be involved in photosynthesis in hemp plants.These results demonstrate the potential of Fe_(3)O_(4)NPs for promoting hemp growth and decreasing the THC content at low doses. | Canhui Deng Qing Tang Zemao Yang Zhigang Dai Chaohua Cheng Ying Xu Xiaojun Chen Xiaoyu Zhang Jianguang Su | 2022 | Frontiers of Environmental Science & Engineering2022，16，10： | 0 |
| 16 | Quality Evaluation of Threshing and Redrying Process Based on Analytic Hierarchy Process显示文摘Improving the stability of the homogenization process to achieve the homogeneity of tobacco products is one of important targets for the redrying industry.According to the specification for threshing and redrying process,a total of 14 indicators in three categories that affect the quality of the threshing and redrying process were selected.Using analytic hierarchy process,combined with expert experiences,a judgment matrix was constructed to conduct consistency test.The weights of indices in production were obtained.This will help in evaluating the actual production quality,finding the weak links of process and adjusting the parameters of the corresponding links in a targeted manner,thereby improving the quality of production process. | Xiaohan GUO Chaohua TANG Jing TAN Qiuguo WU Bowen XIE Zhuangyu CHEN | 2020 | Asian Agricultural Research2020，12，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员