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| 1 | Epididymis-specific lipocalin promoters显示文摘我们的目标是译解序列它 DNA 为附睾基因的 tissue-specificexpression 被要求。至少 6 epididymis 特定的 lipocalin 基因被知道。这些不同地在附睾被调整并且区域化。Lipocalin 5 (Lcn5 或 mE-RABP ) andLipocalin (Lcn8 或 mEP17 ) 8 是属于 epididymis 特定的 lipocalin 基因簇的相应基因。两个都, Lcn5 基因和 5.3 kb 倡导者的 5 kb 倡导者碎片直接 theLcn8 基因罐头碎裂在附睾(到远侧的头的 Lcn5 和到起始的片断的 Lcn8 ) 的 transgene 表示,显示这些倡导者碎片为 epididymis 特定的基因表示包含重要 cis-regulatoryelement。为了定义,推进调整基因表示的碎片, Lcn5 倡导者在转基因的鼠标被检查并且使附睾房间线不朽。在连续删除以后, Lcn5 基因的 1.8 kb 倡导者碎片是在转基因的老鼠的足够的 fortissue 特定、区域特定的基因表示。短暂 transfectionanalysis 表明抄写因素叉头框 A2 ( Foxa2 )与雄激素受体交往并且绑在 Lcn5 倡导者 activity.Immunohistochemistry 感应的雄激素依赖者显示了的 kb 和 1.3 kb 和 thatFoxa2 表示禁止的在 1.2 之间的 Lcn5 倡导者的 100 bp 碎片在附睾的 Foxa2 的一个限制表达式在哪儿 endogenousLcn5 基因表示被压制并且 Lcn5 倡导者的 Foxa2 抑制与在语料库和尾的 Lcn5 的表示的缺乏一致。我们的途径为附睾 lipocalin 基因规定的进一步的分析和 epididymalfunction 的灵活控制提供基本策略。 | Kichiya Suzuki Xiuping Yu Pierre Chaurand Yoshihiko Araki Jean-Jacques Lareyre Richard M. Caprioli Marie-Claire Orgebin-Crist Robert J. Matusik | 2007 | Asian Journal of Andrology2007，9，4： | 3 |
| 2 | Environmental impacts of steel slag reused in road construction: A crystallographic and molecular (XANES) approach显示文摘 | Perrine Chaurand Jerome Rose Valérie Briois Luca Olivi Jean-Louis Hazemann Olivier Proux Jérémie Domas Jean-Yves Bottero | 2006 | Journal of Hazardous Materials2006，，3： | 2 |
| 3 | Potential of dry fractionation of wheat bran for the development of food ingredients, part I: Influence of ultra-fine grinding显示文摘 | Youna Hemery Marc Chaurand Ulla Holopainen Anna-Maija Lampi Pekka Lehtinen Vieno Piironen Abdelkrim Sadoudi Xavier Rouau | 2010 | Journal of Cereal Science2010，，1： | 2 |
| 4 | Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis 显示文摘 | Norris JL Cornett DS Mobley JA Andersson M Seeley EH Chaurand P | 2007 | Int J Mass Spectrom2007，260，23： | 1 |
| 5 | Synergistic effects of sulfate reducing bacteria and zero valent iron on zinc removal and stability in aquifer sediment显示文摘 | KUMAR N CHAURAND P ROSE J | 2015 | Chemical Engineering Journal2015，260，： | 1 |
| 6 | Profiling proteins from azoxymethane-induced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry显示文摘 | Chaurand P DaGue B B Pearsall R S | 2001 | Proteomics2001，1，10： | 1 |
| 7 | Identification,immunolocalization,regulation,and postnatal development of the lipocalin EP17(epididymal protein of 17 kilodaltons)in the mouse and rat epididymis显示文摘 | Lareyre JJ Chaurand P at al | 2003 | Endocrinology2003，144，3： | 1 |
| 8 | Peptide and protein identification by matrix-assisted laser desorption ionization (MALDI) and MALDI-post-source decay time-of-flight mass spectrometry显示文摘 | CHAURAND P LUETZENKIRCHEN F SPENGLER B | 1999 | J Am Soc Mass Spectrom1999，10，2： | 1 |
| 9 | Potential of dry fractionation of wheat bran for the development of food ingredients, part I: influence of ultra-fine grinding显示文摘 | Hemery Y Chaurand M Holopainen U | 2011 | Journal of Cereal Science2011，53，2： | 1 |
| 10 | Direct profiling of proteins in biological tissue sections by MALDI mass spectrometry显示文摘 | Chaurand P Stoeckli M Caprioli RM | 1999 | Anal Chem1999，71，23： | 1 |
| 11 | Changes in common wheat grain milling behavior and tissue mechanical properties following ozone treatment 显示文摘 | Desvignes C Chaurand M Dubois M | 2007 | Journal of Cereal Science2007，，： | 1 |
| 12 | Kinetics of steel slag leaching: batch tests and modeling显示文摘 | Laurent De Win& Perrine Chaurand Jerome Rose | 2011 | Waste Manage2011，31，： | 1 |
| 13 | Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry显示文摘 | Chaurand P Caprioli RM | 2002 | Electrophoresis2002，23，18： | 1 |
| 14 | Advances in proteomic strategies toward the early detec- tion of lung cancer 显示文摘 | HASSANEIN M RAHMAN J S CHAURAND P | 2011 | Proc Am Thorac Soc2011，8，2： | 1 |
| 15 | Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues显示文摘 | STOECKLI M CHAURAND P HALLAHAN D E | 2001 | Nature Med2001，7，4： | 1 |
| 16 | MALDI imaging mass spectrometry: molecular snapshots of biochemical systems显示文摘 | CORNETT D S REYZER M L CHAURAND P | 2007 | Nat Methods2007，4，10： | 1 |
| 17 | Imaging mass spectrometry: a new tool to investigate the spatial organization of peptides and proteins in mammalian tissue sections显示文摘 | CHAURAND P SCHWARTZ S A CAPRIOLI R M | 2002 | Curr Opin Chem Biol2002，6，5： | 1 |
| 18 | Imaging mass spectrometry:a new technology for the analysis of protein expression in mammalian tissues显示文摘 | Stoeckli M Chaurand P Hallahan DE | 2001 | Nat Med2001，7，4： | 1 |
| 19 | Profiling and imaging of proteins in tissue sections by MS显示文摘 | CHAURAND P SCHWARTZ S A CAPRIOLI R M | 2004 | Anal Chem2004，76，5： | 1 |
| 20 | Profiling proteins from azoxymethane-lnduced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry 显示文摘 | Chaurand P DaGue BB Pearsall RS | 2001 | Proteomics2001，1，10： | 1 |
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