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| 1 | Small interfering RNA-based molecular therapy of cancers显示文摘RNA interference(RNAi)has become a gold standard for validating gene function in basic life science research and provides a promising therapeutic modality for cancer and other diseases.This minireview focuses on the potential of small interfering RNAs(siRNAs)in anticancer treatment,including the establishment and screening of cancer-associated siRNA libraries and their applications in anticancer drug target discovery and cancer therapy.This article also describes the current delivery approaches of siRNAs using lipids,polymers,and,in particular,gold nanoparticles to induce significant gene silencing and tumor growth regression. | Wei Guo Wangbing Chen Wendan Yu Wenlin Huang Wuguo Deng | 2013 | Chinese Journal of Cancer2013，32，9： | 5 |
| 2 | Nanoengineering core / shell structured brucite @ polyphosphate @ amine hybrid system for enhanced flame retardant properties显示文摘 | Wang Xuesong Pang Hongchang Chen Wendan | 2013 | Polymer Degradation and Stability2013，98，12： | 1 |
| 3 | In vitro selection of glyphosate-tolerant variants from long-term callus cultures of Zoysia matrella [L.] Merr显示文摘 | Shu Chen Mingliang Chai Yufang Jia Zhongshan Gao Li Zhang Minxia Gu Wendan Lin Liping Wang | 2012 | Plant Cell Tissue and Organ Culture (PCTOC)2012，，2： | 1 |
| 4 | Nanoengineering core/shell structured brucite@polyphosphate@amine hybrid system for enhanced flame retardant properties显示文摘 | Wang Xuesong Pang Hongchang Chen Wendan | 2013 | Polymer Degradation and Stability2013，98，12： | 1 |
| 5 | Telomere-to-telomere assembly of cassava genome reveals the evolution of cassava and divergence of allelic expression显示文摘Cassava is a crucial crop that makes a significant contribution to ensuring human food security.However,high-quality telomere-totelomere cassava genomes have not been available up to now,which has restricted the progress of haploid molecular breeding for cassava.In this study,we constructed two nearly complete haploid resolved genomes and an integrated,telomere-to-telomere gap-free reference genome of an excellent cassava variety,‘Xinxuan 048’,thereby providing a new high-quality genomic resource.Furthermore,the evolutionary history of several species within the Euphorbiaceae family was revealed.Through comparative analysis of haploid genomes,it was found that two haploid genomes had extensive differences in linear structure,transcriptome features,and epigenetic characteristics.Genes located within the highly divergent regions and differentially expressed alleles are enriched in the functions of auxin response and the starch synthesis pathway.The high heterozygosity of cassava‘Xinxuan 048’leads to rapid trait segregation in the first selfed generation.This study provides a theoretical basis and genomic resource for molecular breeding of cassava haploids. | Xin-Dong Xu Ru-Peng Zhao Liang Xiao Liuying Lu Min Gao Yu-Hong Luo Zu-Wen Zhou Si-Ying Ye Yong-Qing Qian Bing-Liang Fan Xiaohong Shang Pingli Shi Wendan Zeng Sheng Cao Zhengdan Wu Huabing Yan Ling-Ling Chen Jia-Ming Song | 2023 | Horticulture Research2023，10，11： | 0 |
| 6 | 拟杆菌Bacteroides sp Pif1蛋白解旋酶机制的结构与功能探究显示文摘Pif1蛋白是一个保守的DNA解旋酶,属于SF1B家族成员。Pif1通过解旋双链DNA(dsDNA)、DNA/RNA杂合体、G4结构等,参与基因组稳定性维持的调控过程。 | Xianglian Zhou Wendan Ren SakshibeeduR.Bharath Xuhua Tang Yang He Chen Chen Zhou Liu Dewang Li 宋海卫 | 2017 | 科学新闻2017，19，4： | 0 |
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