|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of extracorporeal bioartificial liver support system on fulminant hepatic failure rabbits显示文摘AIM To evaluate the possibility of usingcultured human hepatocytes as a bridge betweenbioartificial liver and liver transplantation.METHODS In this experiment,the efficacy ofextracorporeal bioartificial liver support system(EBLSS)consisting of spheriodal human livercells and cultured hepatocytes supernatant wasassessed in vivo using galactosamine inducedrabbit model of fulminant hepatic failure.RESULTS There was no difference of survivalbetween the two groups of rabbits,but in thesupported rabbits serum alanineaminotransferase,total bilirubin and creatininewere significantly lower and hepatocyte necrosiswas markedly milder than those in controlanimals.In addition,a good viability of humanliver cells was noted after the experiment.CONCLUSION EBLSS plays a biologic role inmaintaining and compensating the function ofthe liver. | Wang YJ Li MD Wang YM Chen GZ Lu GD Tan ZX | 2000 | World Journal of Gastroenterology2000，6，2： | 17 |
| 2 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 3 | Effect of HSP70 antisense RNA on normal sorghum pollen formation显示文摘IT has been found that heat shock proteins (hsp) exist universally in animals, plants, microbesand human beings. Some of hsps possess functions of molecular chaperons, such as hsp60,hsp70 and hsp90, which participate in folding and assembling polypeptides to functional struc-tures and transferring them into suitable sites. They also undertake repairing damaged cellularDNA and nucleolus. Therefore, they are house-keeping proteins and play an importantrole in maintaining normal cellular life and functions and in cellular response to environmentalstresses. There exists high homology in DNA sequence among the hsp of the same molecularweight across species. We have first reported the close relationship between hsps | Chen, JN Fu, HY Lu, ZX Qin, HY Zhang, L Guo, ZB | 1997 | Chinese Science Bulletin1997，42，23： | 2 |
| 4 | DNA methylation and demethylation in mammals 显示文摘 | Chen ZX Riggs AD | 2011 | J Biol Chem2011，286，18： | 1 |
| 5 | Decreased tobacco-specific nitrosamines by microbial treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing process of burley tobacco 显示文摘 | Wei XT Deng XW Cai DB Ji ZX Wang CJ Yu J Li JP and Chen SW | 2014 | J Agric Food Chem2014，62，12： | 1 |
| 6 | Expanding the use of arsenic trioxide: Leukemias and beyond显示文摘 | Chen Z Chen GQ Shen ZX | 2002 | Semin Hematol2002，39，21： | 1 |
| 7 | DNA methylation and demethylation in mammals显示文摘 | Chen ZX Riggs AD | 2011 | J Biol Chem2011，286，18： | 1 |
| 8 | Microbe-assisted sulfide oxidation in the anode of a microbial fuel cell显示文摘 | Sun M Mu ZX Chen YP | | 0，，09： | 1 |
| 9 | Yanan Shaanxl area comprehen- sive preliminary investigation of renal syndrome hemorrhagic fever with natural foci 显示文摘 | Chen YP Jia ZX Yang XJ | 2003 | Shanxi Medical Journal2003，32，12： | 1 |
| 10 | Differential expression profiles of microRNAs in NIH3T3 cells in response to UVB irradiation 显示文摘 | Guo L Huang ZX Chen XW | 2009 | Photochem Photobio12009，85，3： | 1 |
| 11 | Chinese culture permeation in the treatment of Parkinson disease: a cross - sectional study in four regions of China 显示文摘 | Zhang ZX Chen H Chen SD | 2014 | BMC Res Notes2014，30，： | 1 |
| 12 | Effects of mitochondrial potassium channel and membrane potential on hypoxic human pulmonary artery smooth muscle cells显示文摘 | Hu HL Zhang ZX Chen CS | 2010 | Am J Respir Cell Mol Biol2010，42，6： | 1 |
| 13 | Reference material for PSA: the IFCC standardization study 显示文摘 | Stamey TA Chen ZX Prestigiacomo AF | 1998 | Clin Biochem1998，31，6： | 1 |
| 14 | Use of arsenic trioxide(As2O3)in the treatment of acute promyelocytic leukemia(APL):Ⅱ Clinical efficacy and pharmacokinetics in relapsed patients显示文摘 | Shen ZX Chen GQ Ni JH | 1997 | Blood1997，89，9： | 1 |
| 15 | Identification of Oet4-activating compounds that enhance reprogramming efficiency 显示文摘 | Li W Tian E Chen ZX | 2012 | Proc Natl Acad Sci USA2012，109，20： | 1 |
| 16 | ent-Kaurene Diterpenoids from Isodon rubescens显示文摘 | Li BL Chen SN Shi ZX | 2000 | Phytochemistry2000，，： | 1 |
| 17 | Impact of Climate Change on Water Resources in the Tarim River Basin显示文摘 | Xu ZX Chen YN Li JY | 2004 | Water Resources Management2004，18，5： | 1 |
| 18 | DNA methylation and demethylation in mammals显示文摘 | Chen ZX Arthur D | 2011 | J Biol Chem2011，286，18： | 1 |
| 19 | Application of statistical method- ology to the optimization of fermentative medium for carotenoids production by Rhodobacter sphaeroides 显示文摘 | Chen DM Han YB Gu ZX | 2006 | Process Biochemis- try2006，41，： | 1 |
| 20 | Loyahy to supervisors organizational commitment : Relationships to employee performance in China显示文摘 | Chen ZX Tsui AS Farh JL | 2002 | Journal of Occupational and Organizational2002，75，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员